DynaChrom Single-Use Chromatography System: Conductivity Control For Linear And Step Gradients

Accurate conductivity control is essential for consistent chromatography performance, influencing peak resolution, product recovery, impurity clearance, and overall product quality. The Thermo Scientific™ DynaChrom™ Single-Use Chromatography System uses closed-loop, model-based control to correct conductivity deviations in real time across flow rates from 6 to 1,980 L/hr. Integrated with the Thermo Scientific™ TruChrom™ automation platform on the Emerson™ DeltaV™ DCS, the system supports stable step and linear gradients while minimizing overshoot, settling time, and manual tuning. Precise control also enables inline dilution at high-dilution ratios, reducing buffer preparation, storage, facility footprint, and manual handling.

Access the full application to explore performance results across multiple flow rates and dilution scenarios to see how adaptive control can improve gradient accuracy, scale translation, and more.