06.17.26 -- Downstream Decisions To Maximize Viral Vector Yields And Reduce COGs

Automated filtration systems streamline PUPSIT, leak testing, and integrity checks to ensure sterile drug product processing. Learn how these methods improve contamination control and compliance.

Explore how chromatography resins are evolving from purification tools to therapeutic agents in cancer treatment, with insights into their chemical properties and clinical potential.

Evaluate surface treatments, scalability, and contamination risks to select the right adherent platform. Testing early ensures a seamless transition from benchtop to production.

Master the fundamentals of identifying and monitoring process-related impurities. Ensure biologic safety and regulatory success by optimizing your analytical strategy.

Understanding how to fine-tune pH and ionic strength allows for the detection of truncated sequences and single-nucleotide variants, turning complex purification challenges into reproducible data.

Proper packing for resin is crucial to prevent issues like cracking or channeling which can lead to process disruptions and product loss.

Fill‑finish is evolving as biologics and advanced therapies shift capacity and sterility needs. Automation, emerging tech, and data‑driven methods are boosting efficiency in aseptic production.

Ensuring container closure integrity in an increasingly complex pharmaceutical industry requires a holistic approach that incorporates quality control into all phases of product design and development.

Manual ADC filling demands 30 labor hours per batch, introduces contamination risk, and leaves product recovery to chance. See how automation cut that to 2 hours with ROI in under a year.

Proper formulation development has a huge impact on whether a technology transfer to clinical phase fill/finish is successful. Review the challenges of transitioning a promising drug candidate.