08.18.25 -- Derisk Your Stem Cell Therapy Process With Modular Systems

Learn how to optimize mesenchymal stem cell (MSC) production from isolation to large-scale expansion. Discover methods and technologies for consistent, high-quality cell yields for therapeutic applications.

Occasional breakthroughs in stem cell research, such as the discovery of mesenchymal stem/stromal cells (MSCs) or the development of induced pluripotent stem cells, showcase the potential of this field. Investigate important considerations for working with three different stem cell types: MSCs, induced pluripotent stem cells, and neural stem cells.

Bone marrow-derived MSCs are commonly studied due to their ease of access and achievable therapeutic dosage. Here, we demonstrate the utility of the HYPERStack 36-layer cell culture vessel as a tool to meet the growing demand for expanding bone marrow-derived MSCs to relevant scale for clinical application workflows.

Discover how high-quality, multipotent stromal cells are efficiently produced for regenerative medicine. Learn about their impressive viability and critical marker expression for therapeutic uses.

As cell therapy trials advance from pre-clinical research to late-stage trials, cell culture platforms will need to meet increasing demands for cell yield. In this study, the CellCube system was used for expansion of two commonly used bioproduction cell lines – HEK293T and Vero - resulting in final harvest yields for both HEK293T and Vero cell lines greater than 10 billion cells.

Scaling up stem cell production presents unique hurdles. Discover crucial considerations, from initial development to large-scale manufacturing, to ensure cell quality and successful outcomes.