Producing MSC-Derived Cell Therapies From Isolation To Large-Scale Expansion; A Journey Of Workflows, Technologies, And Case Studies

Mesenchymal Stem/Stromal Cells (MSCs) are leading the way in therapeutic applications due to their self-renewal, differentiation, immunomodulatory, and anti-inflammatory properties. They play a crucial role in tissue regeneration and repair and are being explored for various clinical applications, including kidney, liver, bone, cartilage, and neurological disorders. This white paper delves into the development of production processes for MSC-based therapies, offering insights into isolation methods, media formulations, and the importance of surface chemistry for optimal cell culture.

Learn about readily available cell expansion technologies and critical considerations for closed systems and cGMP manufacturing. Additionally, explore methods for cell concentration, buffer exchange, and the final packaging, freezing, and storage of MSC products. The content is supported by real-world case studies demonstrating successful MSC manufacturing strategies. Download the full white paper to better understand the entire MSC biomanufacturing process.