01.21.26 -- Avoiding Protein Purification Artifacts That Still Undermine Drug Design

Explore how Isothermal Titration Calorimetry empowers drug discovery, as well as learn about ITC fundamentals, how to eliminate weak candidates, and how to optimize development decisions.

The transition toward complex biologics and patient-centric delivery is redefining sterile manufacturing. Success now depends on adopting flexible production strategies and advanced technologies.

Pharma 4.0 leverages IoT, AI, and automation to enhance drug quality. Evaluate your fill-finish line by considering five key questions on modularity, high-risk process automation, and data integration.

Ensuring container closure integrity in an increasingly complex pharmaceutical industry requires a holistic approach that incorporates quality control into all phases of product design and development.

The predictive models created using “self-validating ensemble modeling (SVEM)” on the definitive screening design data reliably predicted the behavior of the chosen responses.

Downstream processing can account for up to 80% of biopharmaceutical production costs. Optimizing this stage is crucial for resource management, product quality, and overall yield.

Organizations seeking greater efficiency within their downstream purification processes are well-served in considering a single-use, membrane-based solution in lieu of resin-based purification columns.

Gain insight into chromatography fundamentals, resin selection strategies, and the regulatory frameworks required to qualify automated systems for compliant, commercial-scale biologics manufacturing.

Discover how efficient powder-liquid mixing and sterile filtration preserve media integrity and support reproducibility in biopharmaceutical workflows, with promising scalability for larger-volume applications.

Gene therapy is revolutionizing medicine to offer one-time treatments. Find out how AAV vectors are leading the way to optimize production and make these life-changing therapies accessible.