Newsletter | March 10, 2025

03.10.25 -- Areas For Advancement In Peptide Manufacturing

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The rapid advance of ADCs has tested the fine balance between speed to IND and process development that stands up to the rigors of scale-up and transfer. Explore the processes leading ADC developers are employing to mitigate manufacturing-scale risk, and how automation and artificial intelligence are beginning to inform their work. Join Bioprocess Online Live for this interactive discussion. Registration is free thanks to the support of Thermo Fisher Scientific.

FOCUS ON UPSTREAM MANUFACTURING

Areas For Advancement In Peptide Manufacturing

Experts from Eli Lilly, NervGen, and Piramal Pharma Solutions discuss the myriad of ways peptide manufacturing can be improved, drawing on years of industry experience and insight.

Disruptive Technologies Transforming Upstream Process Intensification

The demand for complex biologics is driving the need for intensified cell culture technologies. Perfusion using alternating tangential flow (ATF) is a leading solution to increase cell density and productivity.

The Dynamic Role Of Processing Speed In Cell Separation Outcomes

Explore how the processing speed of cell separation methods impacts product quality, process efficiency, and overall economics.

Efficient Cell Banking In Seed Train Intensification

Gain insight into seed train intensification in upstream development, cell banking, and the challenges of cryopreservation processes from Khalil Essani, the Product Line Manager at Single Use Support.

Non-Viral Gene Modification For Ex-vivo Cell Therapy

Understand the advantages of non-viral transfection technologies for CRISPR- or transposon-based genetic modification and how an improved electroporation technology can support this approach.

Enabling The Development And Manufacturing Of TranspoCART Cells

Learn how an innovative technology streamlines Transpocart cell production, making rapid and consistent manufacturing a reality for cell therapies.

iPSC Expansion In A Cell Expansion System's Small Bioreactor

Explore how using a flexible, automated system can help expand induced pluripotent stem cells (iPSCs) faster than traditional culture methods.

Achieve Higher AAV Productivity With A Next-Gen Transfection Reagent

Learn about a next-generation transfection system that requires 50% less plasmid, decreases transfection reagent consumption, and yields higher AAV productivity to reduce cost per dose.

NEW PODCAST EPISODE

BoB@JPM: Owen Hughes & Brad Sitko, XOMA Royalty

Live from the 2025 JP Morgan Healthcare Conference, The Business of Biotech dives into a game-changing approach to biotech financing with XOMA Royalty’s Owen Hughes & Brad Sitko. They break down their royalty aggregation model, how it mitigates risk, and why it’s an alternative to equity-based funding. Don’t miss this insightful conversation on the future of biotech capital access!

UPSTREAM MANUFACTURING SOLUTIONS

RoosterReplenish hMSC Bioreactor Feed - RoosterBio

Sterile Filtration Solutions - Entegris, Inc.

ELEVECTA Producer Cell Line For Stable, Inducible AAV Production - Cytiva

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