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Discover The Future Of Antibody Purification
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Discover how novel antibody formats are reshaping biologics — and the purification strategies that make them viable. In this white paper, Beyond Traditional Monoclonal Antibodies, Ecolab’s Purolite™ team explores the latest purification technologies tailored for next-generation antibody formats. Learn how novel affinity resins like Praesto™ 70 CH1 and Praesto Jetted A50 HipH are enabling scalable, high-yield production while minimizing aggregation and impurity risks.
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Discover how Ecolab’s partnership with Repligen delivered another important advancement in antibody purification — Praesto CH1 resin. This innovative resin is designed to revolutionize the purification of complex antibody-based therapeutics by binding with high affinity to the CH1 domain of human IgG molecules. Learn about the value of this resin for your applications, as well as the importance of removing contaminants during the capture step. Watch the video here.
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The Praesto AP+ Platform, including the high-performance AP+50 resin, is designed to meet the demands of modern biopharmaceutical purification. Built around a proprietary engineered protein A ligand based on the C domain, these resins offer technical equivalence to legacy platforms ensuring seamless integration into existing workflows with minimal disruption.
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With the current advancement of antibody engineering and drug development, new antibody types such as Fc-fusion proteins and other antibody-derived drugs are emerging. Analyze application data from the use of a new Protein A resin, which enables elution of Fc-containing molecules up to pH 5.0.
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