Newsletter | December 1, 2025

12.01.25 -- An End-To-End Automated HTP Platform For Cell Line Optimization

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Webinar: From Lab To Commercialization: Simplifying Bioprocess Scale-Up

Discover how Thermo Fisher Scientific’s DynaDrive™ Single-Use Bioreactors enable seamless scale-up from 1L to 5,000L. This webinar explores the cuboid design’s mixing advantages, real-world case studies, and strategies to overcome process development challenges. Learn how innovative geometry boosts flexibility, sustainability, and productivity for fed-batch and perfusion applications in process development, MSAT, and manufacturing. Click here to learn more.

FOCUS ON UPSTREAM MANUFACTURING

An End-To-End Automated HTP Platform For Cell Line Optimization

Bristol Myers Squibb's high-throughput stable CHO platform produces high-titer, high-quality material in a fraction of the conventional timeline.

Unlocking ROI And Capacity In Monoclonal Antibody Manufacturing

Perfusion-based upstream production offers up to 24% lower cost and significantly higher productivity than fed-batch, enabling faster timelines, better facility utilization, and improved quality.

Enhance Lab Productivity, Reliability: Shaking Incubator Proactive Service

Regular preventive maintenance is essential for ensuring the longevity and optimal performance of your shaking incubator. Find out how this approach helps avoid costly downtime and protects your research.

Implementing Raman Spectroscopy For Automated Cell Culture Monitoring

Discover how Raman spectroscopy and parallel bioprocessing enable real-time cell culture monitoring, saving time and providing crucial data for process optimization in biopharmaceutical production.

Conversion Of A Viral Glycoprotein Titer Method From ELISA To BLI

In this case study, the analytical development group was provided an ELISA titer method, and the method was redeveloped to operate by biolayer interferometry (BLI) using the ForteBio Octet RED96.

Find The Perfect Balance Between Yield And Desired Glycosylation

Achieving desired glycosylation for therapeutic proteins can be difficult. Explore innovative approaches to optimize this critical quality attribute.

Understanding Adeno-Associated Virus Vector Impurities

AAV vectors hold promise for gene therapy, but removing product-related impurities remains a challenge. Learn how cell line development and process optimization are advancing rAAV production.

Driving Rapid Development Of Complex Biologics

To accommodate the cell expression needs of mAbs, bispecifics, and other advanced multi-specific antibodies, sponsors must leverage a cell line development platform proven to support these modalities.

Rev-Up AAV Genome Production In Upstream Manufacturing

By increasing recombinant AAV titers, this AAV enhancer can help reduce upstream manufacturing costs and lower the cost per therapeutic dose.

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Live Event: How Digital Tools Are Accelerating Biopharma Development

Register today for this digital event led by Bioprocess Online’s chief editor, Tyler Menichiello, features industry experts who will share for an engaging panel discussion on how companies are deploying advanced technologies and tools to accelerate biopharmaceutical development. This event is free to attend thanks to Cytiva.

UPSTREAM MANUFACTURING SOLUTIONS

Welders And Sealers That Deliver Dependable, Sterile Results - Terumo BCT

Cell Culture Media & Supplements - RoosterBio

A Pilot-Scale, Sedimenting Centrifuge - CARR Biosystems

Megatrends For Bioproduction Media And Buffers - Nucleus Biologics

The Next-Gen Cell Line Development Platform Fueling Biologics Success - Abzena

The ExPERT VLx System™ - Superior Transfection Scalability, Efficiency - MaxCyte, Inc.

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