Newsletter | April 16, 2025

04.16.25 -- Amgen's Deep Learning Approach To Vial Inspection

SPONSOR

From Purification to Treatment: Resins in Innovative Therapeutics

Although typically used to purify and analyze biomolecules for therapeutic applications, chromatography resins are now helping to deliver breakthrough therapies for certain cancers and inflammatory diseases. Learn how Bio-Rad’s ion exchange resins serve as carriers of therapeutic agents and provide a robust foundation for advanced drug delivery systems. Read the full article.

FOCUS ON FILL-FINISH

Amgen's Deep Learning Approach To Vial Inspection

The company is testing how artificial intelligence can help bring down the number of false rejections caused by factors like glare on the glass or bubbles in the vial.

Innovation, Tech, And Collaboration In Advanced Materials

Demands for flexible, scalable, cost effective manufacturing are prompting cell and gene therapy manufacturers and CDMOs to implement single-use technology for manufacturing their therapies.

FILL-FINISH SOLUTIONS

Capacity Update January 2025: Fill/Finish - Alcami

Sterile Fill/Finish Services - Bora Pharmaceuticals

SPONSOR

Webinar: PUPSIT Without The Pain: Practical Solutions For Implementation

Join our webinar to explore the critical role of PUPSIT in quality risk management. We’ll cover key risks, including IT methods, wetting, dilution, and recovery, while offering practical solutions for single-use systems. Learn about new standard filtration systems and real-world implementation examples to streamline sterile drug product filtration. Click here to learn more.

FOCUS ON DOWNSTREAM MANUFACTURING

Viral Clearance Under Mild pH Using Protein A Resins

Discover how Praesto Jetted A50 HipH resin offers superior viral clearance at mild pH conditions, minimizing protein aggregation and improving yield during monoclonal antibody purification.

The Buyer's Guide To Oligonucleotide Synthesis

Learn how to produce oligonucleotides at scale with this buyer's guide. Discover the essential equipment, key features, and vendor considerations for successful oligonucleotide synthesis.   

Best Practices In HCP Assay Qualification And Bridging To A New Assay

Explore a case study using a specific HCP immunoassay and advanced orthogonal Antibody Affinity Extraction and Mass Spectrometry methods for assay qualification.

Future Proof Your Process Scale Workflow

Discover how you can future-proof your process scale workflow, from starting bases to tangential flow filtration.

Production Of A Highly Concentrated Monoclonal Antibody

The production of a highly concentrated monoclonal antibody requires many process steps. Discover how to achieve a final mAb concentration above 200 g/L while maintaining critical quality attributes.

Fluorescent Bacterial Colony Selection

Fluorescent reporter genes simplify screening bacterial transformants. Discover a system that automates colony picking to enhance efficiency and precision with fluorescence imaging.

SPONSOR

The debate rages on. While the automation that enables continuous processing gets a lot of hype, there are plenty of dyed-in-the-wool biopharma pros who contend that process optimization and intensification yield comparable benefits, without requiring the capital-intensive process overhaul that continuous demands. Join Bioprocess Online Live for a virtual deep dive into the scalability, sustainability, and capital implications of the continuous-versus-optimized debate. Registration is free thanks to the support of Cytiva.

DOWNSTREAM MANUFACTURING SOLUTIONS

Buffer And Balanced Salt Solutions - Nucleus Biologics

Mini/Maxi Flange Gaskets - Nordson MEDICAL

Connect With Bioprocess Online: