Buffer And Balanced Salt Solutions
Critical in almost every step of viral vector and gene therapy manufacturing processes as well as fundamental aspects of cell therapy process development, buffers are essential tools enabling optimization of vector stability, transfection efficiency, safety, targeting, and regulatory compliance.
Any Bioprocessing Solution Made to Fit Your Needs
Fully Customizable
Easily customize any aspect of buffer or balanced salt solutions, from pH levels and components to testing and packaging configurations.
Transparent Process
Know every component and concentration. Your solution is designed and owned by you, making iteration and scale-up seamless.
Premium Quality
Solutions are manufactured under GMP conditions and governed by strict adherence to an ISO 13485:2016-certified quality system.
Versatility at Every Stage: Any Serotype, Any Resin, Any System
Careful design of buffer solutions can optimize upstream and downstream processes – from cell culture buffers and media to downstream buffers to support filtration, chromatography, TFF just to name a few. We can customize and manufacture any buffer solution for any serotype that conforms to your specifications for all phases of cell and gene therapy development, clinical trials, and commercial manufacturing.
Enhance Flexibility as You Scale With Customizable Buffers
Formulation
Specify your ingredients, concentrations, pH, and grade selection to receive a buffer solution that meets your application criteria.
Volume
Get low-volume quantities of 500 mL to large volumes of up to 2,000L. Want to test an RUO sample of a lightly customized buffer solution?
Packaging
Don’t let packaging define your process! Designed for flexibility, choose from vials, bottles, bags, drums, or any other bioprocessing container to fulfill your specific manufacturing needs.
Testing and Manufacturing
No matter what stage, select either RUO or GMP quality and a variety of testing options and studies, such as sterility, endotoxin, and stability studies.
Your Partner of Choice
Why trust Nucleus Biologics? Simple, experience and expertise. We have formulated and manufactured buffers across the development spectrum for numerous industry collaborators. Develop optimal, individually-owned formulations and unlock the power of versatile buffer design with our innovative solutions tailored for any serotype at any stage. Utilize any resin or system to achieve unparalleled flexibility and efficiency in your processes.