A Simple Solution Slashes Cell Line Development At A Biotech Company

At the end of 2017, Genmab, the largest independent biotech company in Europe, decide that it wanted to speed up development of its growing portfolio of antibody-based therapeutics. The Cell Line Development (CLD) team at Genmab decided to optimise their processes and looked for new equipment that could isolate single cells and provide evidence of clonality in one, single cloning round.

After reviewing the options, the team selected the VIPS™ with Cell Metric® CLD imager combination from Solentim. Jolanda Gerritsen, Technology Expert and Manager of Cell Line Development at Genmab, explained that the VIPS combined with Cell Metric CLD gives her confidence that she has complete control over her cell line development, "unlike fully automated platforms, which are completely different and therefore, it's unknown which cell lines you will select within your CLD process and how the cell lines will behave later in upstream bioreactor fed batch processes."