Harvest & Collection
PRODUCTS
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The Natoli NCF-45 Capsule Filling Machine offers unmatched speed, precision, and versatility for efficient powder and pellet encapsulation, maximizing your production output and minimizing waste.
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MassFerence P2 calibrant for the SamuxMP and SamuxMP Auto
Ref: MP-CON-41015
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bioGO® Mobile cleanrooms for radiopharmaceutical preparation and compounding
Discover Germfree’s custom mobile radiopharmaceutical compounding trailer or single module. These all-in-one facilities seamlessly serve individual hospitals or specialty compounding pharmacies
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LeakZon provides a powerful and versatile platform that adapts to your water management needs. Whether you oversee a small or large operation, LeakZon scales effortlessly to accommodate your requirements. Our seamless integration with various data sources, including GIS Data, AMI, and Billing (CIS), allows for a holistic view of your water network. This comprehensive data integration empowers you to make informed decisions, optimize operations, and maximize efficiency.
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Our in-house custom antibody delivery team has a proven track record of developing antibodies to challenging targets with exacting specifications.
WHITE PAPERS AND CASE STUDIES
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Why A Leading Manufacturing Partner Chose NeoTOP Packaging Machines
Learn how a leading CDMO partnered with Körber to quickly deploy a high-speed packaging solution to meet tight production deadlines in the face of a global pandemic.
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CAR-T And Laminar Flow Glovebox Isolators
A request was made for a containment system that would protect operators during lentivirus transfer, as well as provide a controlled environment for IL-2 charging of media, bead addition, and blood bag spiking.
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ATAD Provides Increased Capacity With No Odors
Faced with persistent odor complaints and limited space, Douglas County Sewer District #1 in East Wenatchee, Washington, turned to the ThermAer second-generation Autothermal Thermophilic Aerobic Digestion (ATAD) system to modernize its biosolids treatment.
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How Optina Diagnostics Used EDC In Earlier Disease Detection
Understand how Optina Diagnostics streamlined operations and achieved significant milestones by leveraging Castor's tools in its effort to revolutionize the diagnostic process for Alzheimer’s.
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Global Start-Up For Multinational Geographic Atrophy Trial
This partnership allowed a leading biopharmaceutical company to navigate the complexities of a Phase IIb study investigating a novel pegylated RNA adapter for geographic atrophy secondary to dry AMD.
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Working Smarter: Empowering Water Operators With Integrated Data
As water utilities face the challenges of sustainability, efficiency, and service quality, digital technology has become a necessity. The right tech can help deliver reliable service, optimize systems, and meet sustainability goals, but integrating the data streams these solutions generate can offer even greater gains – allowing utilities to move faster and achieve more powerful outcomes.
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Water Disinfection At Feldschlöesschen Brewery In Switzerland
Despite meeting European drinking water standards, contamination levels at a brewery reached as high as 800 CFU/ml, prompting the brewery to seek a reliable disinfection solution to protect the integrity of its production processes.
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Mobile Gowning Cleanroom, Built To Meet ISO 7 Requirements
Uncover how Germfree designed and installed a mobile cGMP cleanroom on a 53′ tractor-trailer chassis to provide a flexible and efficient cleanroom solution tailored to the company’s needs.
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Data Key In Addressing Patient Recruitment Challenges
Explore how a Phase II trial for extensive-stage and previously treated small cell lung cancer overcame recruitment challenges with a data-driven solution designed to surface protocol-matched patients.
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RO Membrane Protection For A Desalination Plant In Mejillones, Chile
Read about a seawater desalination plant that presented with several performance issues and chose the HOD UV system to control biofouling on the RO membranes.
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Minnetonka, MN Pilots Acoustic Pipe Assessment Prior To Road Resurfacing
A Minnesota suburb used non-invasive acoustic technology to assess an aging water main before a 20-year road construction moratorium. This critical data allowed them to confidently prioritize pipe renewals and better manage their infrastructure budget.
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Improving Patient Health And Safety: SOPs And Process Mapping
In this study, a biotech company faced compliance challenges due to inadequate SOPs that lacked detailed process maps. Propharma stepped in to provide a strategy and project plan.
NEWS
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Baden-Württemberg's Largest Solar Park Now In Operation5/28/2025
EnBW has commissioned its solar park in Langenenslingen-Wilflingen (district of Biberach in the southwest of Germany).
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Puraffinity Signs First Commercial Agreement For Full-Scale Deployment Of Its PFAS Removal Technology6/2/2025
The agreement was signed with Envytech Solutions, the leading expert in mobile water treatment in the Nordic region and a member of the Sortera Group, which operates across the Nordics and the UK.
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Redex Preloaded Systems Deliver Precise Positioning For Machine Tools1/16/2025
Redex is pleased to announce its patented DualDRIVE and TwinDRIVE preloading technologies now give CNC machine designers several ways to build a zero backlash system.
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Consulta Remedios Selects Kevel's Retail Media Cloud To Power Its Next-Generation Advertising Platform5/2/2025
Kevel, the leading provider of API-based retail media ad serving technology, today announced that Consulta Remédios, Brazil's largest medicine price comparison platform, has selected Kevel's Retail Media Cloud to power the development and enhancement of its in-house retail media network.
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Meatable And TruMeat Collaborate To Accelerate Cost-Effective Cultivated Meat Production4/30/2025
Meatable, the leader in cultivated meat technology, and TruMeat, specializing in the contract manufacturing of cultivated meat at commercial scale, have formed a strategic collaboration to advance the global commercialization of cultivated meat.
ABOUT
Harvest and Collection
Harvest and collection is the process used to retrieve biological agents and vaccines present in cell cultures or to harvest and collect stem cells from blood or bone marrow. Many bioresearch companies have sophisticated systems for harvesting and collecting cells. These systems make counting cells easier and they also protect against contamination.
Cells are harvested once the cells reach a density level in the cell culture medium that precludes further growth. The best time to harvest cells is when they are in a confluent state (at least 50% of the culture dish is covered and before 100% of the dish is covered).
Cells can be harvested using on of three methods: Mechanical, using Proteolytic enzymes, or using EDTA. Mechanical harvesting uses a rubber spatula to remove the cells from the growth surface or culture. This method is quick but can cause many cells to die because it is highly disruptive. This method is favored when harvesting lots of different samples of cells to prepare extracts.
In this case, viability of the cells doesn’t matter. Three enzymes; Trypsin, Collagenase, and Pronase can be used in combination with EDTA. The combination of these enzymes with the EDTA makes cells detach from the growth medium.
This method is easy but also has a downside. It can damage the cell surface by eating up exposed cell surface proteins. EDTA can be used alone to detach cells from their medium and it is gentler than using trypsin.
Normally, collected cells are placed in a new suspension, or growth medium to continue growing new cultures. This is referred to as passaging or splitting the cells.