Harvest & Collection
PRODUCTS
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![Gallery_MDF-DU503VHA_front_Large]( "Ultra-Low Temperature Freezer With Enhanced Security Features")
PHCbi brand's 18.6 cu.ft (528L) ultra-low temperature freezer offers the flexibility of operating on both 115V or 220V with the switch of a power cord. This model provides enhanced security features and operates at only 4.99kWh per day. SMART features include three lock methods: facial recognition, keypad, or optional proximity card. ENERGY STAR® Certified.
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![tycon]( "TY-CON™ Conductive Gasket")
The patented U.S. Pipe TY-CON Conductive Gaskets are for use in Ductile-Iron pipe and fittings provided with the time proven TYTON JOINT®, and HDSS® restrained joint. TY-CON gaskets are intended to provide pipe joint conductivity for thawing service connections in cold climates.
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![Compounding Aseptic Containment Isolator]( "Aseptic Containment Isolator For Compounding")
Germfree’s Compounding Aseptic Containment Isolators use HEPA filters to provide the highest level of operator and product protection.
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![LiCellGrow]( "Cell Expansion Bioreactor System")
Visualize continuous metabolic changes in cells in real-time and adjust cell culture conditions automatically for enhanced cell quality.
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![Leica Stellaris bucket]( "STELLARIS DLS Digital Light Sheet Microscope")
Light Sheet Re-Imagined
STELLARIS 5 and STELLARIS 8 Digital LightSheet (DLS) unite in one place a confocal system and a light sheet microscope – a unique combination aimed to make your research more versatile. The exclusive vertical design of DLS, enabled by Leica Microsystems’ proprietary TwinFlect mirrors, allows you to combine confocal and light sheet imaging in the same system, so you can easily adapt the microscopy method to your experimental needs.
WHITE PAPERS AND CASE STUDIES
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![regeneron-cgmp-gowning-cleanroom-5]( "Mobile Gowning Cleanroom, Built To Meet ISO 7 Requirements")
Mobile Gowning Cleanroom, Built To Meet ISO 7 RequirementsUncover how Germfree designed and installed a mobile cGMP cleanroom on a 53′ tractor-trailer chassis to provide a flexible and efficient cleanroom solution tailored to the company’s needs.
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![hydraforce-agitator]( "Revolutionizing Wastewater Management In Four Cities Through Water Mixing")
Revolutionizing Wastewater Management In Four Cities Through Water MixingHistorically, lift station operators have turned to chemical treatments as the primary means of managing grease buildup. However, these methods carry inherent drawbacks.
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![GettyImages-1400967286 regulations computer]( "Optimizing Early-Stage Oncology")
Optimizing Early-Stage OncologyA strategic partnership enables a U.S. biotech company to address the struggles with their Phase I first-in-human oncology trial.
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![GettyImages-974024224-molecule string-molecule cluster]( "Leveraging Surface Plasmon Resonance For Characterizing Ternary Complexes")
Leveraging Surface Plasmon Resonance For Characterizing Ternary ComplexesUncover how Surface Plasmon Resonance (SPR) can be used to gain real-time, label-free insights into PROTAC binding kinetics and ternary complex formation.
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![GettyImages-1152357186 data, AI]( "Data Key In Addressing Patient Recruitment Challenges")
Data Key In Addressing Patient Recruitment ChallengesExplore how a Phase II trial for extensive-stage and previously treated small cell lung cancer overcame recruitment challenges with a data-driven solution designed to surface protocol-matched patients.
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![GettyImages-1759287088 patient nurse consultation]( "Reducing The Burden Of Patient Retention And Improving Continuity")
Reducing The Burden Of Patient Retention And Improving ContinuityImmunology trials often place a sustained burden on participants. However, integrating Home Trial Support (HTS) into a Phase 3 immunology trial can help improve the overall study experience.
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![GettyImages-525755915 clinical team eCOA]( "Improving Patient Health And Safety")
Improving Patient Health And SafetyEngage an experienced CMC program management consultant to collaboratively develop and maintain a robust product development plan (PDP) with your team lead, cross-functional members, and vendors.
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![GettyImages-2103894533 office, team, coworkers, meeting]( "Accelerating Early Phase Oncology Study Development")
Accelerating Early Phase Oncology Study DevelopmentExplore a close collaboration to co-develop a comprehensive, adaptive protocol designed to support key decisions across multiple trial phases for an innovative cancer therapy.
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![GettyImages-1159306148 aeration biosolids]( "Cutting Costs, Not Corners: How PRI-TECH® Transformed Biosolids Odor Control At Bergen Point WWTP")
Cutting Costs, Not Corners: How PRI-TECH® Transformed Biosolids Odor Control At Bergen Point WWTPThe Suffolk County Department of Public Works tested the effectiveness and cost-efficiency of PRI-TECH® in controlling odors at a wastewater treatment plant. The technology successfully treated odors and reduced operating costs.
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![Digital Checklist GettyImages-1465188429]( "Using Virtual Study Coordinators For EDC Entry And Query Resolution To Speed Up Data Access And Cleaning")
Using Virtual Study Coordinators For EDC Entry And Query Resolution To Speed Up Data Access And CleaningThe piece showcases how the effective use of CRIO can significantly enhance site performance, supporting recruitment and diversity objectives for sponsors.
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![GettyImages-2217581928 manufacturing, production]( "Developing A Project Management Office (PMO) At A Small Manufacturing Site")
Developing A Project Management Office (PMO) At A Small Manufacturing SiteDiscover how implementing a Project Management Office transformed a small manufacturing site into a high-performing, strategic asset within a global network.
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![Aqua Aerobic]( "Rushville Installs AquaStorm® Cloth Media Filters To Treat Combined Sewer Overflow Discharge Instead Of Conventional Wet Weather Storage Tank")
Rushville Installs AquaStorm® Cloth Media Filters To Treat Combined Sewer Overflow Discharge Instead Of Conventional Wet Weather Storage TankDiscover why, rather than installing a costly stormwater storage tank, the City of Rushville partnered with Aqua-Aerobic Systems to pilot the AquaStorm Cloth Media Filter.
NEWS
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New Land Grant Research Detects Dicamba Damage From The Sky7/9/2025
Drones can now detect subtle soybean canopy damage from dicamba at one ten-thousandth of the herbicide’s label rate — simulating vapor drift — eight days after application.
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KBR Expands Support For Saudi's Energy Future1/22/2025
KBR announced today it has been awarded a contract to support sustainable production of energy resources in Saudi Arabia by contributing to the delivery of Saudi Aramco’s Master Expansion Program and increasing gas handling capacity at key regional locations.
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Canada Accelerates Transition To Zero-Emissions Vehicles8/13/2025
Canada is leading the way on the infrastructure, innovation and partnerships required to transition to electric transportation.
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How Lakes Connect To Groundwater Critical For Resilience To Climate Change7/9/2025
The study drew on data from 350 lakes across 18 European countries, collected between 2022 and 2024, to provide a comprehensive picture of how the continent’s lakes are coping with climate change.
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Smarter Dentistry Starts Here: Muskan.AI Enhances Diagnostics, Imaging & Patient Care5/19/2025
Muskan.AI, a pioneer in the application of artificial intelligence to dentistry, has reached several key milestones in its mission to transform dental care through intelligent, accessible, and clinician-focused technology.
ABOUT
Harvest and Collection
Harvest and collection is the process used to retrieve biological agents and vaccines present in cell cultures or to harvest and collect stem cells from blood or bone marrow. Many bioresearch companies have sophisticated systems for harvesting and collecting cells. These systems make counting cells easier and they also protect against contamination.
Cells are harvested once the cells reach a density level in the cell culture medium that precludes further growth. The best time to harvest cells is when they are in a confluent state (at least 50% of the culture dish is covered and before 100% of the dish is covered).
Cells can be harvested using on of three methods: Mechanical, using Proteolytic enzymes, or using EDTA. Mechanical harvesting uses a rubber spatula to remove the cells from the growth surface or culture. This method is quick but can cause many cells to die because it is highly disruptive. This method is favored when harvesting lots of different samples of cells to prepare extracts.
In this case, viability of the cells doesn’t matter. Three enzymes; Trypsin, Collagenase, and Pronase can be used in combination with EDTA. The combination of these enzymes with the EDTA makes cells detach from the growth medium.
This method is easy but also has a downside. It can damage the cell surface by eating up exposed cell surface proteins. EDTA can be used alone to detach cells from their medium and it is gentler than using trypsin.
Normally, collected cells are placed in a new suspension, or growth medium to continue growing new cultures. This is referred to as passaging or splitting the cells.