Harvest & Collection
PRODUCTS
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This wideband Class AB GaN power amplifier delivers robust RF performance across an expansive frequency range from 50 MHz to 6 GHz, supporting applications that span commercial wireless systems, broadband communications, lab environments, and defense technologies.
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We support you in the process of optimally implementing complex Manufacturing Execution Systems. In addition to the creation of Master Batch Records (MBRs) and Electronic Batch Recording (EBR), including classic data acquisition and preparation, as well as all other processes that have immediate effects on the manufacturing process.
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Every capsule and tablet begins with an idea. It takes a professional and innovative manufacturing partner to turn that idea into a reality. Enter Natoli, a name synonymous with excellence in pharmaceutical equipment and services. From the early stages of formulation to the grand scale of full-blown production, Natoli offers a seamless journey through every step of the process. Whether you’re unsure of how to start or how to finish, Natoli can guide the way.
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Providing around-the-clock support, enabled by at least two QPs per assignment, delivering full continuity, and reduced risk.
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The HLM-40ABH is a high-power, wideband signal limiter designed for protection and performance in RF systems operating from DC up to 40 GHz.
WHITE PAPERS AND CASE STUDIES
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Enhancing Site Capacity For Clinical Trials With DCT Nurses
See how the rapid deployment of trained mobile nurses was able to mitigate resource-related obstacles and facilitate timely patient enrollment for a pediatric rare disease trial.
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Addressing A Global Health Priority In Australia And New Zealand
For sponsors navigating a competitive therapeutic landscape, this case underscores how regional execution excellence can accelerate global impact.
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Enabling MSC Harvest, Wash, And Concentration
A study demonstrates how a low-shear, closed-system centrifuge achieved over 90% MSC recovery and minimized viability loss, supporting scalable cell therapy manufacturing.
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Eclipse Gear Pumps For Chemical Dosing: Middlesex Water Company
Pulsafeeder’s Eclipse pumps provide successful chemical dosing at the Middlesex Water Company in Highland Park, New Jersey.
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Development To Large-Scale cGMP Production
For manufacturers working with a dry powder medium (DPM), early consultation with a supplier can increase the likelihood of success. Uncover a two-phase scale-up strategy for the production of DPM.
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Why Sherbrooke, Quebec Chose Pinnacle Zenith Ozone Generators To Boost Water Treatment Efficiency
Sherbrooke, Quebec upgraded its water treatment plant with Pinnacle’s Zenith ozone system, improving disinfection, reliability, energy efficiency, and operational savings while ensuring future scalability.
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Avoiding Unplanned Outages In Water Treatment
Maintenance professionals within water and wastewater Treatment facilities are as busy as ever. To keep up with growing demands on their time, they are always looking for ways to improve the reliability and maintenance requirements within their scope of responsibility.
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The Role Of Peptones In Boosting Monoclonal Antibody Production
Peptones have become a key tool in CHO cell bioprocessing, enhancing monoclonal antibody yield and quality.
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Driving Seamless Tech Transfer Of Multiple Projects Within A Short Timeline
Uncover how we were able to provide seamless technology transfers and uninterrupted production to deliver critical therapies efficiently and reliably to patients.
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Achieving Faster Timelines And Cost Savings Through Digital Validation
Examine how the Project Ready program was leveraged to streamline validation processes for a CDMO, resulting in a 25% reduction in budget and faster project completion.
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BSL-3 Mobile Biocontainment Laboratory For Vaccine Development Research
The client required a freestanding COVID-19 research facility on an accelerated timeline built for continuous use in the cold climate of the northeast United States without a shell building.
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Overcoming Analytical Bottlenecks In Oligonucleotide Drug Development With Automation
Growing oligonucleotide complexity is straining traditional analytical workflows. See how automated LC‑UV‑MS processing offers a scalable way to boost throughput and reduce manual effort.
NEWS
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Rivers Choose Their Path Based On Erosion — A Discovery That Could Transform Flood Planning And Restoration7/10/2025
Rivers are Earth’s arteries. Water, sediment and nutrients self-organize into diverse, dynamic channels as they journey from the mountains to the sea.
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New Milestone For RIBER In Silicon Photonics With A ROSIE Order In The United States9/8/2025
8:00 am - RIBER, a global market leader in molecular beam epitaxy (MBE) equipment for the semiconductor industry, announces a new order for a ROSIE system from a new US-based customer specialized in quantum computing.
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FF-10832 Granted FDA Orphan Drug Designation For The Treatment Of Biliary Tract Cancer7/7/2025
FUJIFILM Pharmaceuticals U.S.A., Inc., drug development center and a leading provider of Contract Development and Manufacturing Organization (CDMO) services for drug delivery system (DDS) technologies, today announced that the U.S.
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Sticking To Innovation: The Surprising Role Of Tape In terahertz Photonics8/20/2025
Could the key to next-generation photonic devices be hiding in your drawer? For Professor Jean-Michel Ménard, an ordinary roll of tape proved essential in building groundbreaking terahertz filters that are set to transform wireless tech, imaging and diagnostics.
ABOUT
Harvest and Collection
Harvest and collection is the process used to retrieve biological agents and vaccines present in cell cultures or to harvest and collect stem cells from blood or bone marrow. Many bioresearch companies have sophisticated systems for harvesting and collecting cells. These systems make counting cells easier and they also protect against contamination.
Cells are harvested once the cells reach a density level in the cell culture medium that precludes further growth. The best time to harvest cells is when they are in a confluent state (at least 50% of the culture dish is covered and before 100% of the dish is covered).
Cells can be harvested using on of three methods: Mechanical, using Proteolytic enzymes, or using EDTA. Mechanical harvesting uses a rubber spatula to remove the cells from the growth surface or culture. This method is quick but can cause many cells to die because it is highly disruptive. This method is favored when harvesting lots of different samples of cells to prepare extracts.
In this case, viability of the cells doesn’t matter. Three enzymes; Trypsin, Collagenase, and Pronase can be used in combination with EDTA. The combination of these enzymes with the EDTA makes cells detach from the growth medium.
This method is easy but also has a downside. It can damage the cell surface by eating up exposed cell surface proteins. EDTA can be used alone to detach cells from their medium and it is gentler than using trypsin.
Normally, collected cells are placed in a new suspension, or growth medium to continue growing new cultures. This is referred to as passaging or splitting the cells.