Harvest & Collection
PRODUCTS
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![VSX3746]( "X-Band 1.5 kW GaN High Power Solid State Power Amplifier: VSX3746")
The VSX3746 is a high-power X-band solid-state power amplifier (SSPA) that operates within the 9.0–10.0 GHz frequency range and delivers a nominal peak RF output of 1.5 kW, with a minimum of 1.2 kW.
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![e-Builder-Screenshot_Water-Online-450x300_42224]( "Trimble e-Builder")
As the industry’s most advanced digital construction management system, Trimble e-Builder enables efficiencies across the entire design-build lifecycle, with a smooth transition to the operation phase. Reduce risk, enhance collaboration and improve outcomes using the industry-leading digital project delivery software for owners.
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![Mettler-Toledo - X52]( "X-Ray Inspection: X52")
A premium dual energy x-ray inspection system offering outstanding detection of hard-to-find, low density contaminants, in a variety of applications. Available in standard and custom configurations.
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![Medicine-pills-tablets-GettyImages-545993684]( "USP<1062> Tablet Compression Characterization")
Natoli Scientific takes pride in its comprehensive USP<1062> Tablet Compression Characterization services, tailored to address the complexities of tableting in pharmaceutical manufacturing. Staying true to the parameters outlined in the United States Pharmacopeia (USP) Chapter 1062, our approach meticulously evaluates tablet compression behaviors. By thoroughly characterizing the compression profile, we can pinpoint the optimal compression force required to form a cohesive tablet without applying undue stress that could lead to capping — the separation of tablet tops during or after the compression phase.
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![Scientist-with-tablet-GettyImages-950594528]( "Unlocking Pharmaceutical Success: From Idea To Reality")
In the pharmaceutical industry, every capsule and tablet begins with a concept. Transforming that idea into a tangible product requires an expert manufacturing partner. Natoli stands out as a leader in pharmaceutical equipment and services, providing a comprehensive journey from formulation to full-scale production.
WHITE PAPERS AND CASE STUDIES
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![dunea]( "Collaborative Tech: How Dunea Is Boosting Network Visibility And Resilience")
Collaborative Tech: How Dunea Is Boosting Network Visibility And ResilienceIntegrating high-frequency sensor data with digital twins enhances network visibility and accelerates response times. This collaborative approach allows utilities to detect anomalies instantly, optimize maintenance, and simulate operational scenarios to ensure long-term system resilience.
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![RZ3000-11]( "Drinking Water Disinfection At Lunenberg, Massachusetts, USA Local Community")
Drinking Water Disinfection At Lunenberg, Massachusetts, USA Local CommunityIn this case study, read how the Lunenburg Water District improved their water disinfection system with the installation of an Atlantium RZ300-11 HOD UV system. The system effectively disinfects water, meets future demands, and eliminates chlorine taste and odor.
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![Nordson - extruded tubing]( "Innovative Multilayer Extrusion Technology Solves Product Redesign Challenges")
Innovative Multilayer Extrusion Technology Solves Product Redesign ChallengesA multinational medical device company successfully worked to redesign a component used in cardiovascular surgery.
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![GettyImages-157291618 Scientist inspecting vial]( "Leveraging High-Pressure Sterile Filtration For Highly Viscous Solutions")
Leveraging High-Pressure Sterile Filtration For Highly Viscous SolutionsThis research demonstrates the potential of high-pressure sterile filtration to enhance efficiency, reduce waste, and accelerate the development of innovative therapies.
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![GettyImages-1869998947-doctor-patient]( "Supporting Participants Through National Travel Disruptions")
Supporting Participants Through National Travel DisruptionsA sudden travel shutdown threatened a critical clinical visit. Rapid rescheduling, coordinated logistics, and clear communication ensured engagement and the ability to continue without interruption.
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![GettyImages-139602926 labeling, packaging, pharma]( "Secondary Packaging: Labeling, Cartoning, Clamshell, And Stretch Carding")
Secondary Packaging: Labeling, Cartoning, Clamshell, And Stretch CardingTight timelines and coordinated packaging execution drove a high-stakes product launch ahead of a national competitor, ultimately capturing over half the market and setting a new benchmark.
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![GettyImages-181879520-crushed-tablet-powder]( "Expanding The OSD Toolbox: An Industry Approach To Adsorb Lipids Onto Powder Substrates")
Expanding The OSD Toolbox: An Industry Approach To Adsorb Lipids Onto Powder SubstratesExplore innovative solutions for improving the solubility and bioavailability of poorly soluble compounds in solid oral dosage forms to enhance drug delivery and therapeutic effectiveness.
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![GettyImages-1185624320-scientist-lab-smiling]( "Can Your Biopharma Team Keep Unplanned Downtime At Bay?")
Can Your Biopharma Team Keep Unplanned Downtime At Bay?Learn how teams reduce downtime, strengthen compliance, and respond quickly to equipment issues through proactive maintenance, smart spare parts planning, and digital troubleshooting tools.
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![240327_BMJ1L8A6473]( "Leveraging Single-Use Solutions To Solve Working Cell Bank Challenges")
Leveraging Single-Use Solutions To Solve Working Cell Bank ChallengesDiscover how custom manifolds enhance allogeneic therapy development from formulation to commercialization by improving process control, scalability, and efficiency.
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![proteoanalyzer-agilent-lab]( "A New Story For Myoglobin—Producing Yeast-Generated Alternative")
A New Story For Myoglobin—Producing Yeast-Generated AlternativeA fast, automated protein analysis workflow empowers researchers to screen yeast strains more efficiently. See how this streamlined approach accelerates innovation while supporting sustainability.
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![biologic-medicine-research-GettyImages-1413606459]( "WuXiHigh 2.0 Delivers A 180 mg/mL Formula")
WuXiHigh 2.0 Delivers A 180 mg/mL FormulaThis case study shows how smart formulation and integrated development achieved a stable 180 mg/mL biologic for subcutaneous delivery, for teams tackling concentration issues.
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![GettyImages-525755915 clinical team eCOA]( "Improving Patient Health And Safety")
Improving Patient Health And SafetyEngage an experienced CMC program management consultant to collaboratively develop and maintain a robust product development plan (PDP) with your team lead, cross-functional members, and vendors.
NEWS
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Plants Don't Just Feel The Heat – They Decode It Through A Molecular Network6/13/2025
In a new framework that could reshape how we engineer crops for a warming world, scientists have revealed that plants don't rely on a single "thermometer" to sense temperature.
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Quantum Biopharma Announces Signing Of An Agreement With A Global Pharmaceutical Contract Research Organization To Prepare An IND (Investigational New Drug) Application Package For Lucid-21-302 (Lucid-MS), A First-In-Class Treatment For Multiple Sclerosis5/20/2025
Quantum BioPharma Ltd. (NASDAQ: QNTM) (CSE: QNTM) (FRA: 0K91) (“Quantum BioPharma” or the “Company”), a biopharmaceutical company dedicated to building a portfolio of innovative assets and biotech solutions, today announces that it has signed an agreement with a global pharmaceutical contract research organization to prepare an IND (Investigational New Drug) application package for Lucid-21-302 (Lucid-MS) with the US FDA.
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From Everyday To Extreme, Toolant Launches Brand New Line Of Hand Tools8/15/2025
Today, toolant, a tool and accessories brand built around real-world needs, announced the launch of its brand new hand tools collection designed for automotive enthusiasts and professional car detailers alike.
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Drawing Inspiration From Ancient Chemical Reactions3/20/2025
To help find solutions to the planet’s climate crisis, MIT Associate Professor Daniel Suess is looking to Earth’s ancient past.
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Smarter Dentistry Starts Here: Muskan.AI Enhances Diagnostics, Imaging & Patient Care5/19/2025
Muskan.AI, a pioneer in the application of artificial intelligence to dentistry, has reached several key milestones in its mission to transform dental care through intelligent, accessible, and clinician-focused technology.
ABOUT
Harvest and Collection
Harvest and collection is the process used to retrieve biological agents and vaccines present in cell cultures or to harvest and collect stem cells from blood or bone marrow. Many bioresearch companies have sophisticated systems for harvesting and collecting cells. These systems make counting cells easier and they also protect against contamination.
Cells are harvested once the cells reach a density level in the cell culture medium that precludes further growth. The best time to harvest cells is when they are in a confluent state (at least 50% of the culture dish is covered and before 100% of the dish is covered).
Cells can be harvested using on of three methods: Mechanical, using Proteolytic enzymes, or using EDTA. Mechanical harvesting uses a rubber spatula to remove the cells from the growth surface or culture. This method is quick but can cause many cells to die because it is highly disruptive. This method is favored when harvesting lots of different samples of cells to prepare extracts.
In this case, viability of the cells doesn’t matter. Three enzymes; Trypsin, Collagenase, and Pronase can be used in combination with EDTA. The combination of these enzymes with the EDTA makes cells detach from the growth medium.
This method is easy but also has a downside. It can damage the cell surface by eating up exposed cell surface proteins. EDTA can be used alone to detach cells from their medium and it is gentler than using trypsin.
Normally, collected cells are placed in a new suspension, or growth medium to continue growing new cultures. This is referred to as passaging or splitting the cells.