Harvest & Collection
PRODUCTS
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Free your safety and clinical teams to focus on what matters most.
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Pharmaceutical Checkweighing systems weigh and count products in motion, rejecting those that fail to meet exacting specifications.
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Every capsule and tablet begins with an idea. It takes a professional and innovative manufacturing partner to turn that idea into a reality. Enter Natoli, a name synonymous with excellence in pharmaceutical equipment and services. From the early stages of formulation to the grand scale of full-blown production, Natoli offers a seamless journey through every step of the process. Whether you’re unsure of how to start or how to finish, Natoli can guide the way.
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The Dual Seal Variable Volume Precision Dispense Pump is a robust, stepper motor-driven positive displacement pump designed for reliable dispensing of complex fluids, including those with high surfactant content or crystallization tendencies.
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CPI EDB presents the VSS3607 GaN solid state power amplifier (SSPAs) operating in the S-band (2.7 – 2.9 GHz). These high efficiency, high power, compact amplifiers are easy to maintain, and are designed for use in air surveillance radar applications.
WHITE PAPERS AND CASE STUDIES
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Advanced Ozone Disinfection – City Of Fayetteville, Arkansas
Discover how Fayetteville upgraded wastewater disinfection with advanced ozone technology, improving contaminant removal, reducing energy use, and delivering reliable, sustainable treatment for future regulatory demands.
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BSL-3 Mobile Biocontainment Laboratory For Vaccine Development Research
The client required a freestanding COVID-19 research facility on an accelerated timeline built for continuous use in the cold climate of the northeast United States without a shell building.
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Enhancing Clinical IP Efficiency & Compliance
A U.S.-based clinical research sponsor optimized their supply chain visibility, reduced costs and risks, and improved efficiency by replacing their manual inventory management system.
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How Can You Avoid Bioprocessing Risks When Using Cable Ties?
Cable ties in bioprocessing can cause leaks, damage, and delays. See how switching to a uniform-sealing connector can significantly improve efficiency, reduce prep time, and minimize contamination risks.
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Using eConsent Data To Populate Site And Sponsor Data Systems
A top-10 pharmaceutical company was looking to reduce the amount of administrative burden on their clinical trial sites and themselves. See how we accomplished it, using eConsent.
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Municipal Effluent Treatment In India
Discover how an agency balanced effective disinfection while minimizing environmental impact and ensuring the safety of both the public and workers in its wastewater treatment practices.
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Enabling Gene Therapy Access Using A Cell-Based Companion Diagnostic (CDx)
This study highlights how we overcame developmental challenges by employing a customized approach that leveraged scientific expertise, strategic collaboration, and effective governance.
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Standardize Flow Cytometry Data With Easy Assay Transfer Across Sites
Gain insight into how a global pharmaceutical company successfully transferred their cell therapy assays across international locations.
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Optimal Syringe Carton Design To Meet Drug Manufacturers' Needs
Learn about the advantages of an optimal packaging design and the resulting benefits of its implementation to the overall process.
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SL-RAT At Little Rock Water Reclamation Authority
Little Rock looked to enhance their sophisticated cleaning program and reduce sanitary sewer overflow count by implementing new technologies.
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Revolutionizing Viral Infectious Disease Research And Drug Discovery
Learn how Organ-Chips are being used to rapidly identify promising treatments, investigate virus evolution, and analyze how mechanical forces influence the innate immune response to viral infections.
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eSource For A COVID Treatment Trial
Unearth how this emerging biopharmaceutical company was able to overcome challenges to successfully facilitate a Phase 2 trial for a COVID-19 treatment in critically ill patients.
NEWS
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New Sensaphone Sentry Remote Monitoring System: Next-Generation Alternative To Legacy Landline Auto Dialers5/12/2025
The new Sensaphone Sentry remote monitoring system is an ideal replacement for traditional landline-based auto dialer devices that are becoming obsolete because they rely on outdated, often unsupported, copper telephone lines.
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Repligen Corporation & Univercells Technologies Partner TO Enable Real-Time Monitoring OF Viral Vector And Vaccine Biomanufacturing7/9/2025
Univercells Technologies, a Donaldson Life Sciences business and global provider of bioprocessing solutions, announced a collaboration with Repligen Corporation to integrate real-time monitoring capabilities and enhance the development and manufacturing of viral vectors and vaccines.
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INTECH: TRUMPF Uses AI To Improve Laser Cutting Edges3/18/2025
At its in-house INTECH trade fair, TRUMPF is showcasing its “Cutting Assistant,” an application which uses artificial intelligence to improve the quality of laser-cut edges.
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Researchers Uncover Role Of A-Site Cation Ordering In Perovskite Anodes For High-Temperature Oxygen Evolution7/28/2025
Solid oxide electrolysis cells (SOECs) are a leading technology for carbon dioxide reduction and energy conversion, offering high current densities, excellent Faradaic efficiency, and low overpotentials. Perovskite oxides are commonly used as SOEC anodes, yet the impact of A-site cation ordering on their oxygen evolution reaction (OER) kinetics remains unexplored.
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As The PIC Ecosystem Grows, So Grows The Future Prospects For PICs5/2/2025
One debate that continues within the integrated photonics community is how far, or rather how soon, integrated photonics will transform data centres into more efficient, monolithic computing platforms for AI.
ABOUT
Harvest and Collection
Harvest and collection is the process used to retrieve biological agents and vaccines present in cell cultures or to harvest and collect stem cells from blood or bone marrow. Many bioresearch companies have sophisticated systems for harvesting and collecting cells. These systems make counting cells easier and they also protect against contamination.
Cells are harvested once the cells reach a density level in the cell culture medium that precludes further growth. The best time to harvest cells is when they are in a confluent state (at least 50% of the culture dish is covered and before 100% of the dish is covered).
Cells can be harvested using on of three methods: Mechanical, using Proteolytic enzymes, or using EDTA. Mechanical harvesting uses a rubber spatula to remove the cells from the growth surface or culture. This method is quick but can cause many cells to die because it is highly disruptive. This method is favored when harvesting lots of different samples of cells to prepare extracts.
In this case, viability of the cells doesn’t matter. Three enzymes; Trypsin, Collagenase, and Pronase can be used in combination with EDTA. The combination of these enzymes with the EDTA makes cells detach from the growth medium.
This method is easy but also has a downside. It can damage the cell surface by eating up exposed cell surface proteins. EDTA can be used alone to detach cells from their medium and it is gentler than using trypsin.
Normally, collected cells are placed in a new suspension, or growth medium to continue growing new cultures. This is referred to as passaging or splitting the cells.