Harvest & Collection
PRODUCTS
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The AMP20162 solid state high-power amplifier is designed for EMI/RFI testing, laboratory use, and general communication applications.
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The C20-1500WG is a high-performance WR-15 waveguide directional coupler engineered for precision measurement and signal monitoring in millimeter-wave systems.
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This standard rack-mounted amplifier features a Class AB linear GaN hybrid design, delivering full X-Band instantaneous bandwidth from 8 to 12 GHz.
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Natoli Scientific takes pride in its comprehensive USP<1062> Tablet Compression Characterization services, tailored to address the complexities of tableting in pharmaceutical manufacturing. Staying true to the parameters outlined in the United States Pharmacopeia (USP) Chapter 1062, our approach meticulously evaluates tablet compression behaviors. By thoroughly characterizing the compression profile, we can pinpoint the optimal compression force required to form a cohesive tablet without applying undue stress that could lead to capping — the separation of tablet tops during or after the compression phase.
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Every capsule and tablet begins with an idea. It takes a professional and innovative manufacturing partner to turn that idea into a reality. Enter Natoli, a name synonymous with excellence in pharmaceutical equipment and services. From the early stages of formulation to the grand scale of full-blown production, Natoli offers a seamless journey through every step of the process. Whether you’re unsure of how to start or how to finish, Natoli can guide the way.
WHITE PAPERS AND CASE STUDIES
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Designing Protocols For A 40% Emulsifiable Concentrate Of A Systemic Insecticide
Explore how formulation expertise can help overcome the complex challenges of developing stable, effective, and regulatory-compliant emulsifiable concentrate (EC) formulations for crop protection.
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Leeton Shire Improves Efficiency And Service Levels With An Affordable, Intuitive Digital Solution
Although Leeton Shire already had some digital technologies in place, such as SCADA, GIS and AMI, they lacked hydraulic modeling capabilities and expertise — which is why they turned to Qatium’s open and secure water management platform.
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Case Study: Global Oncology
Scout's transportation, expense reimbursement, and time and wage loss compensation helped an oncology study recruit and retain hard-to-reach patients.
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CRO Takes Trial Build Times From Weeks To Days
Recognizing the inefficiencies in traditional build processes, a top global CRO partnered with Medable to transform its approach to clinical trial launch.
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AVT - AVT EZ Valve Install Keeps Work On Track At German Oil Refinery
Industrial repairs at height require lightweight, efficient solutions to maintain production schedules. Under-pressure valve insertion allows for the rapid creation of isolation points on elevated pipelines, ensuring system continuity and safety without the need for extensive shutdowns.
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Enhancing Clinical Supply Chain With Signant SmartSignals Supplies
A global pharma leader improved supply chain efficiency and compliance by digitalizing processes with Signant's SmartSignals Supplies, achieving better visibility, traceability, and reduced errors.
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Recruiting & Retaining More Patients Per Site:
Through Home Trial Support (HTS) services, MRN is able to enhance the accessibility of clinical trials while reducing the emotional toll on their patients suffering from loss of mobility.
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Aseptic Expertise And Delivery Of Services
A pharmaceutical services company sought expert intervention after a routine requalification of their aseptic simulation process revealed a contaminated unit, halting commercial production for two months.
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Revolutionizing Biofilm Research: High-Resolution, Real-Time Imaging with ZeGage Optical Profiler
A university lab optimized biofilm research with Zygo’s ZeGage Optical Profiler, enabling high-resolution, real-time, non-contact imaging that accelerates data collection, enhances accuracy, and preserves biofilm integrity.
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Rapid Assessment Of Fab-VHH Expression
Find out how a 10-day expression screening program rapidly identified optimal gene orientation for a bi-specific antibody fragment fusion, achieving up to 570 µg/mL soluble, active product.
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Successful SwissMedic Marketing Authorization Application For An Oncology Therapy
See how strategic EU dossier adaptation and Swiss-specific regulatory expertise enabled a successful SwissMedic submission and accelerated market access for an oncology therapy.
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Digitalizing Batch Records In Pharmaceutical Production
Pharma manufacturing embraces cutting-edge automation, yet outdated paper-based documentation hinders efficiency and delays batch releases. See how digital solutions can transform compliance.
NEWS
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ROO.AI Adds Automated Warranty Management To Help Businesses Reduce Maintenance Costs5/27/2025
ROO.AI announced today the availability of a new connected worker platform module for Warranty Management to simplify the process of identifying repairs under warranty and recovering warranty repair costs.
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New Milestone For RIBER In Silicon Photonics With A ROSIE Order In The United States9/8/2025
8:00 am - RIBER, a global market leader in molecular beam epitaxy (MBE) equipment for the semiconductor industry, announces a new order for a ROSIE system from a new US-based customer specialized in quantum computing.
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INTECH: TRUMPF Uses AI To Improve Laser Cutting Edges3/18/2025
At its in-house INTECH trade fair, TRUMPF is showcasing its “Cutting Assistant,” an application which uses artificial intelligence to improve the quality of laser-cut edges.
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Spearhead Bio Awarded NSF Tech Transfer Grant To Accelerate Development Of Improved Corn Varieties7/14/2025
Spearhead Bio, a biotechnology startup revolutionizing crop genome engineering through the use of plants' own natural DNA, has been awarded a Small Business Technology Transfer (STTR) Phase I grant from the U.S. National Science Foundation (NSF).
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Repligen Corporation & Univercells Technologies Partner TO Enable Real-Time Monitoring OF Viral Vector And Vaccine Biomanufacturing7/9/2025
Univercells Technologies, a Donaldson Life Sciences business and global provider of bioprocessing solutions, announced a collaboration with Repligen Corporation to integrate real-time monitoring capabilities and enhance the development and manufacturing of viral vectors and vaccines.
ABOUT
Harvest and Collection
Harvest and collection is the process used to retrieve biological agents and vaccines present in cell cultures or to harvest and collect stem cells from blood or bone marrow. Many bioresearch companies have sophisticated systems for harvesting and collecting cells. These systems make counting cells easier and they also protect against contamination.
Cells are harvested once the cells reach a density level in the cell culture medium that precludes further growth. The best time to harvest cells is when they are in a confluent state (at least 50% of the culture dish is covered and before 100% of the dish is covered).
Cells can be harvested using on of three methods: Mechanical, using Proteolytic enzymes, or using EDTA. Mechanical harvesting uses a rubber spatula to remove the cells from the growth surface or culture. This method is quick but can cause many cells to die because it is highly disruptive. This method is favored when harvesting lots of different samples of cells to prepare extracts.
In this case, viability of the cells doesn’t matter. Three enzymes; Trypsin, Collagenase, and Pronase can be used in combination with EDTA. The combination of these enzymes with the EDTA makes cells detach from the growth medium.
This method is easy but also has a downside. It can damage the cell surface by eating up exposed cell surface proteins. EDTA can be used alone to detach cells from their medium and it is gentler than using trypsin.
Normally, collected cells are placed in a new suspension, or growth medium to continue growing new cultures. This is referred to as passaging or splitting the cells.