Harvest & Collection
PRODUCTS
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Hot air sterilization tunnels are used to continuously depyrogenate pharmaceutical glass items, such as vials and syringes, after they are washed and before they enter a filling machine.
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The N-332 linear stage, powered by PICMAWalk, the longest-lasting piezo-motorized drive principle on the market, delivers an impressive 75 N active force with a 3 nm minimum incremental motion.
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The Natoli NCF-45 Capsule Filling Machine offers unmatched speed, precision, and versatility for efficient powder and pellet encapsulation, maximizing your production output and minimizing waste.
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For a nasal spray production fill-finish solution that offers unparalleled versatility, look no further! The Hull i-Dositecno BI and MI Nasal Spray Filling Machines simplify your manufacturing workflow to enable accurate and consistent rotary filling, stoppering and capping. With simple servo-driven motion-controlled design they can fill up to 50 or 200 units per minute (upm).
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Visualize continuous metabolic changes in cells in real-time and adjust cell culture conditions automatically for enhanced cell quality.
WHITE PAPERS AND CASE STUDIES
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Thales Receives Custom 10PW Beam Dump For World's Most Powerful Laser
By collaborating with Gentec-EO and their distributor Laser Components, see how Thales was able to gather the necessary specifications and requirements for this project.
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A New Story For Myoglobin—Producing Yeast-Generated Alternative
A fast, automated protein analysis workflow empowers researchers to screen yeast strains more efficiently. See how this streamlined approach accelerates innovation while supporting sustainability.
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Rapid Results In A High-Stakes Dry Eye Disease Trial
This time-sensitive Phase 3 trial in dry eye disease required precision project management leveraging strong site relationships, ophthalmology-specific expertise, and data-driven site selection.
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No More Swiss Holes: Filling The Gaps In Clinical Trial Disclosure
This use case shows how sponsors can gain clarity on disclosure requirements when entering a new country.
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Explore A High-Performing Basal Medium And Feed Pairing
A customer sought to replace a chemically defined CHO medium with a more efficient medium and feed pairing strategy in bioreactors.
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How Optina Diagnostics Used EDC In Earlier Disease Detection
Understand how Optina Diagnostics streamlined operations and achieved significant milestones by leveraging Castor's tools in its effort to revolutionize the diagnostic process for Alzheimer’s.
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Global Start-Up For Multinational Geographic Atrophy Trial
This partnership allowed a leading biopharmaceutical company to navigate the complexities of a Phase IIb study investigating a novel pegylated RNA adapter for geographic atrophy secondary to dry AMD.
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FSP And IVD Clinical Trials
This study highlights the benefits of ProPharma's FSP services for clinical trials, including scalability, risk reduction, cost savings, and timely delivery.
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AEC PFAS Removal System Reduces PFAS Contamination In New Jersey
This case study demonstrates the effectiveness of a new technology for removing PFAS from well water to below the EPA’s detection limits.
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GxP Inventory Delivers Real-Time Visibility, Operational Efficiency
Modernize your clinical supply chain to streamline global trial operations, ensure regulatory compliance, and deliver investigational therapies to patients efficiently and reliably.
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Robust, Scalable Strategy For Monodisperse Nanosuspensions Of Poorly Soluble Drugs
By tailoring the formulation strategy, selecting the appropriate excipients, and fine-tuning process conditions, see how our team was able to improve bioavailability and in vivo exposure.
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Satellite-Based Infrastructure Intelligence For Advanced Leak Detection Technology
Satellite-based radar technology allows water utilities to identify non-surfacing leaks that traditional methods often miss. By pinpointing underground moisture signatures, municipalities can significantly reduce non-revenue water and meet conservation goals through more efficient, data-driven field inspections.
NEWS
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ZEISS Introduces The New Smartzoom 100: The Future Of Digital Microscopy For Efficient Optical Inspections5/6/2025
ZEISS presents the new ZEISS Smartzoom 100, an innovative digital microscope for fast and efficient quality assurance.
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PNE Group Receives Permits For Three New Wind Farms In Germany7/8/2025
In the second quarter of 2025, the PNE Group received the necessary permits for the construction and operation of three onshore wind farms in the German states of Brandenburg, Hesse, and North Rhine-Westphalia.
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Pocket Alarm Detects And Records RF/Microwave Directed Energy Weapons, Nuclear Events, And Terrestrial Gamma Bursts5/8/2025
Ultraview Corp’s EM/GAMMALERT is a new pocket device that warns of RF/microwave jammer and directed energy weapon deployment1 - an emerging threat speculated as a modality in “Havana Syndrome”.
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Baden-Württemberg's Largest Solar Park Now In Operation5/28/2025
EnBW has commissioned its solar park in Langenenslingen-Wilflingen (district of Biberach in the southwest of Germany).
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Be Part of Photonics Future: CIOE 2025 Visitor Registration Live Now!4/9/2025
The 26th China International Optoelectronic Exposition (CIOE 2025) is set to take place from September 10–12, 2025, at the Shenzhen World Exhibition & Convention Center, spanning 240,000 square meters of exhibition space.
ABOUT
Harvest and Collection
Harvest and collection is the process used to retrieve biological agents and vaccines present in cell cultures or to harvest and collect stem cells from blood or bone marrow. Many bioresearch companies have sophisticated systems for harvesting and collecting cells. These systems make counting cells easier and they also protect against contamination.
Cells are harvested once the cells reach a density level in the cell culture medium that precludes further growth. The best time to harvest cells is when they are in a confluent state (at least 50% of the culture dish is covered and before 100% of the dish is covered).
Cells can be harvested using on of three methods: Mechanical, using Proteolytic enzymes, or using EDTA. Mechanical harvesting uses a rubber spatula to remove the cells from the growth surface or culture. This method is quick but can cause many cells to die because it is highly disruptive. This method is favored when harvesting lots of different samples of cells to prepare extracts.
In this case, viability of the cells doesn’t matter. Three enzymes; Trypsin, Collagenase, and Pronase can be used in combination with EDTA. The combination of these enzymes with the EDTA makes cells detach from the growth medium.
This method is easy but also has a downside. It can damage the cell surface by eating up exposed cell surface proteins. EDTA can be used alone to detach cells from their medium and it is gentler than using trypsin.
Normally, collected cells are placed in a new suspension, or growth medium to continue growing new cultures. This is referred to as passaging or splitting the cells.