Harvest & Collection
PRODUCTS
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![Aseptic-Pharmaceutical-Isolators-from-Franz-Ziel]( "Aseptic Pharmaceutical Isolators From Franz Ziel")
Isolators with product protection as a housing for aseptic processes, e.g., filling, loading and unloading of freeze dryers.
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![teledyne]( "HiRel Semiconductors Releases Wideband 50 GHz RF Switch")
Teledyne HiRel Semiconductors has announced the release of the TDSW050A2T, a high-performance, rad-tolerant RF switch designed for demanding aerospace and defense applications.
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![business-people-shaking-hands-GettyImages-908944978]( "Functional Service Provider (FSP)")
At ProPharma, we offer a unique approach to the traditional Clinical Research Organization (CRO) Full-Service Provider (FSP) model.
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![S-Band GaN Solid State Power Amplifier (SSPA): VSS3607]( "S-Band GaN Solid State 1.3 kW Power Amplifier Module: VSS3607")
CPI EDB presents the VSS3607 GaN solid state power amplifier (SSPAs) operating in the S-band (2.7 – 2.9 GHz). These high efficiency, high power, compact amplifiers are easy to maintain, and are designed for use in air surveillance radar applications.
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![Curebase app ePRO- feature]( "A Single Digital Experience Participants Will Love")
Experience higher data quality, retention and participant compliance by providing a truly engaging experience from data submission to reminders, appointment management, telemedicine and more -- from the phone, tablet, or desktop.
WHITE PAPERS AND CASE STUDIES
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![GettyImages-545581230-lab-research-computer-tablet-teamwork]( "Media Exchange In iPSC Cell Expansion And Differentiation: A Comparative Study")
Media Exchange In iPSC Cell Expansion And Differentiation: A Comparative StudyLow-shear, closed-system media exchange in iPSC differentiation is vital for scalability. This study compares automated centrifugation to gravity sedimentation, showing equivalent or superior differentiation outcomes.
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![GettyImages-1543830891-direct-to-patient-cell-medicine-order-medication]( "Driving A High-Adherence LTFU Trial Without An EDC")
Driving A High-Adherence LTFU Trial Without An EDCDiscover how our partnership with a client was able to deliver a ten-year long-term follow-up (LTFU) trial that delivered an over 90% adherence rate while keeping trial costs low by not using an EDC.
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![Primrose - VHH]( "Rapid Assessment Of Fab-VHH Expression")
Rapid Assessment Of Fab-VHH ExpressionFind out how a 10-day expression screening program rapidly identified optimal gene orientation for a bi-specific antibody fragment fusion, achieving up to 570 µg/mL soluble, active product.
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![Worker Holding Vaccine Vial GettyImages-1403976499]( "The Most Significant Quality Measurement For Manufacturers")
The Most Significant Quality Measurement For ManufacturersLearn how a life sciences manufacturer generated a contextualized data set that eliminated the manual effort required to curate production data and improved their process in real time.
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![GettyImages-2036497698 clinical lab]( "Generation Of A Contamination Control Strategy")
Generation Of A Contamination Control StrategyAn unaddressed compliance issue related to contamination control can pose a significant risk to a life sciences organization. This case study details a company's journey toward sustainable compliance.
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![Eppendorf - Bioflo control station]( "Large-Scale Exosome Production Stirred-Tank Bioreactors")
Large-Scale Exosome Production Stirred-Tank BioreactorsDiscover how engineered exosomes, displaying tumor-homing peptides, offer a promising tool for targeted cytotoxic drug delivery, produced efficiently with a bioreactor for critical research.
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![cell-therapy-GettyImages-1494029118]( "Case Study: Full Clonality Assessment Of CHO Cell Line")
Case Study: Full Clonality Assessment Of CHO Cell LineIn this case study, a comprehensive genetic analysis was performed on a transgenic Chinese hamster ovary (CHO) master cell bank to characterize the bank and provide high-confidence evidence of clonality.
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![GettyImages-1386672459 international payments]( "Global Vaccine Trials Case Study")
Global Vaccine Trials Case StudyExplore targeted strategies for tackling the complexities of international payments and providing comprehensive participant support in global vaccine trials.
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![GettyImages-1496098113_patient phone]( "Using eConsent Data To Populate Site And Sponsor Data Systems")
Using eConsent Data To Populate Site And Sponsor Data SystemsA top-10 pharmaceutical company was looking to reduce the amount of administrative burden on their clinical trial sites and themselves. See how we accomplished it, using eConsent.
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![Antibodies And Proteins GettyImages-1364886992]( "Innovating The mAb Characterization Process")
Innovating The mAb Characterization ProcessUnderstanding the characteristics of a molecule's "personality" is crucial for optimizing development and manufacturing. Learn how to overcome the challenges in the characterization process.
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![GettyImages-1348093614 mobile visit child]( "Redefining Accessibility For Pediatric Patients")
Redefining Accessibility For Pediatric PatientsExplore how meeting patients where they are can redefine what successful pediatric trial delivery looks like.
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![GettyImages-916906550 catheter]( "Designing, Developing, And Validating A Precision Extruded Tube In Just 8 Weeks")
Designing, Developing, And Validating A Precision Extruded Tube In Just 8 WeeksA multinational medical device company worked to redesign an introducer sheath for a neurovascular microcatheter. After successful prototypes, the design was completed in 8 weeks.
NEWS
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Luceda Photonics Joins Forces With Semitronix To Accelerate Innovation In Integrated Photonics8/12/2025
Luceda Photonics, a leading provider of photonic integrated circuit (PIC) design software, is proud to announce its acquisition by SMTX Technologies Singapore Pte. Ltd., part of Semitronix Group.
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Pasternack's Newest Gain Horn Antennas Include Cage-Style Mounts And Coaxial Adapters1/20/2025
Pasternack, an Infinite Electronics brand and a leading provider of RF, microwave and millimeter-wave products, has launched its new in-house pre-built standard gain horn assemblies featuring coax adapters and antenna mounts.
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New Milestone For RIBER In Silicon Photonics With A ROSIE Order In The United States9/8/2025
8:00 am - RIBER, a global market leader in molecular beam epitaxy (MBE) equipment for the semiconductor industry, announces a new order for a ROSIE system from a new US-based customer specialized in quantum computing.
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Repligen Corporation & Univercells Technologies Partner TO Enable Real-Time Monitoring OF Viral Vector And Vaccine Biomanufacturing7/9/2025
Univercells Technologies, a Donaldson Life Sciences business and global provider of bioprocessing solutions, announced a collaboration with Repligen Corporation to integrate real-time monitoring capabilities and enhance the development and manufacturing of viral vectors and vaccines.
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INTECH: TRUMPF Uses AI To Improve Laser Cutting Edges3/18/2025
At its in-house INTECH trade fair, TRUMPF is showcasing its “Cutting Assistant,” an application which uses artificial intelligence to improve the quality of laser-cut edges.
ABOUT
Harvest and Collection
Harvest and collection is the process used to retrieve biological agents and vaccines present in cell cultures or to harvest and collect stem cells from blood or bone marrow. Many bioresearch companies have sophisticated systems for harvesting and collecting cells. These systems make counting cells easier and they also protect against contamination.
Cells are harvested once the cells reach a density level in the cell culture medium that precludes further growth. The best time to harvest cells is when they are in a confluent state (at least 50% of the culture dish is covered and before 100% of the dish is covered).
Cells can be harvested using on of three methods: Mechanical, using Proteolytic enzymes, or using EDTA. Mechanical harvesting uses a rubber spatula to remove the cells from the growth surface or culture. This method is quick but can cause many cells to die because it is highly disruptive. This method is favored when harvesting lots of different samples of cells to prepare extracts.
In this case, viability of the cells doesn’t matter. Three enzymes; Trypsin, Collagenase, and Pronase can be used in combination with EDTA. The combination of these enzymes with the EDTA makes cells detach from the growth medium.
This method is easy but also has a downside. It can damage the cell surface by eating up exposed cell surface proteins. EDTA can be used alone to detach cells from their medium and it is gentler than using trypsin.
Normally, collected cells are placed in a new suspension, or growth medium to continue growing new cultures. This is referred to as passaging or splitting the cells.