Harvest & Collection
PRODUCTS
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EirGenix is a contract development and manufacturing organization that performs high quality and cost-effective services supporting our clients in development, analytical testing, and GMP manufacturing of biopharmaceuticals from pre-clinical to commercial manufacturing
EirGenix has strong process development capabilities in both microbial and mammalian systems to provide our clients process development, process optimization, and process troubleshooting. We have successfully delivered results to meet clients’ requirement in product productivity, product quality, and process cost effectiveness. Our previous project experience includes recombinant proteins, plasmid DNA, fusion proteins, monoclonal antibodies, and biosimilars.
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When applied to plant influents, hydrogen peroxide destroys dissolved and/or total sulfide that otherwise scavenges Fe3+ added for CEPT and/or chemical phosphorus removal from wastewater. The foundational aspect of this PRI-TECH application (called PRI-CEPT) is that one lb of total sulfide theoretically consumes 3.5 lbs Fe3+ and thus represents an additional cost of $2 – 3 per lb influent sulfide.
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Discover PG&O's expertise in precision polishing & coating for large format optics up to 30", delivering exceptional flatness & surface quality.
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Setting a New Benchmark for Ease of Operation
The NP-255 is a robust tablet press that was built to meet even the most demanding needs of the mid-sized tableting industry. The press has features and options designed to increase production, improve tablet quality, reduce waste, and set a new benchmark for ease of operation. Designed, engineered, and manufactured in the USA, this unique machine has a maximum production speed of 192,000 tablets per hour.
With a hardened steel die table, a gravity feeder that is interchangeable with a two-paddle forced feeder, and our industry-leading intuitive Natoli AIM™ ProPluscontrol system, the NP-255 is the new standard for value in the mid-sized tableting industry.
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Autodesk AutoCAD equips architects, engineers, and construction professionals with precision tools that will provide them with a variety of new capabilities.
WHITE PAPERS AND CASE STUDIES
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Disinfection For Drinking Water Plant In Chennai, India
The Chennai Metropolitan Water Supply and Sewerage Board (CMWSSB) encountered significant challenges in treating high algae loads at its drinking water plant, which processes 1.5 million liters of water daily. The primary issue arose from the organic load in lake water, which, when treated with conventional chlorine disinfectants, resulted in harmful disinfection byproducts (DBPs).
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Cooling Tower Crisis: How Hydrogen Peroxide Scrubbed Away The Bacteria Buildup
A West coast power plant needed an immediate solution to clean its cooling tower that was fast, cost effective, and did not require removal and manual cleaning of the tower's fill material.
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Relieving The Strain Of Publishing During Regulatory Registration
Go inside how an expertly handled NDA submission for a biopharma company ensured timely FDA approval despite challenges.
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Using Virtual Study Coordinators For EDC Entry And Query Resolution To Speed Up Data Access And Cleaning
The piece showcases how the effective use of CRIO can significantly enhance site performance, supporting recruitment and diversity objectives for sponsors.
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ICON And Medable Drive 85% eConsent Adoption In U.S. Menopause Study
A site-focused strategy drove strong eConsent adoption in a complex women’s health study, showing how tailored training and hands-on support boost engagement and compliance.
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Expanding Accessibility In A Phase 3 Influenza Study Through Community-Based Research
By meeting participants where they are, this study sets a new benchmark for inclusive, efficient, and impactful vaccine development.
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Responsible Reclamation – City of Abilene, Texas
To combat drought, Abilene, Texas, implemented a reuse system utilizing O3 + BAC to remove trace organics. This solution met strict standards, ensured water resilience, and proved more cost-effective than AOP alternatives.
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Cell Line Development For High-Titer Lentivirus Vector Production
Explore a groundbreaking method to significantly enhance LV vector yield using engineered HEK293T cells. This approach paves the way for more efficient and large-scale production of LV vectors.
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Safeguarding Neighborhood Service During An Emergency With Valve Insertion
Discover how a municipal utility resolved an urgent infrastructure repair on an active 8-inch water main in just two hours, keeping water flowing to hundreds of nearby residents by avoiding a wide-reaching neighborhood shutdown.
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RO Membrane Protection For A Desalination Plant In Mejillones, Chile
Read about a seawater desalination plant that presented with several performance issues and chose the HOD UV system to control biofouling on the RO membranes.
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Duchenne Muscular Dystrophy Trial In China
A global sponsor conducting a Duchenne Muscular Dystrophy trial in China required reliable patient travel solutions to support children and families.
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Robust, Scalable Strategy For Monodisperse Nanosuspensions Of Poorly Soluble Drugs
By tailoring the formulation strategy, selecting the appropriate excipients, and fine-tuning process conditions, see how our team was able to improve bioavailability and in vivo exposure.
NEWS
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INTECH: TRUMPF Uses AI To Improve Laser Cutting Edges3/18/2025
At its in-house INTECH trade fair, TRUMPF is showcasing its “Cutting Assistant,” an application which uses artificial intelligence to improve the quality of laser-cut edges.
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Almost 49M Tons Of Manure Pose Health Risk For Minnesota's Water5/15/2025
Huge amounts of manure from massive livestock facilities in Minnesota could pollute drinking and recreational water throughout the state, posing a significant health risk.
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ZEISS Supports The Transition Of Spatial Biology To Clinical Research4/28/2025
Today marks the global launch of ZEISS Axioscan 7 spatial biology. The newly optimized slide scanner is the central component of a novel analytical workflow solution portfolio – spanning from sample staining to result reports – tailored to spatial biology applications in clinical research environments.
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Ready-To-Use hiPSC-Derived Cells Help Optimize Lab Workflows2/18/2025
AMSBIO announces a new range of ready-to-use Human induced Pluripotent Stem Cell (hiPSC) -derived cardiomyocytes, hepatocytes, and neurons.
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KRYTAR Celebrating 50-year Anniversary Serving the RF/Microwave Community5/15/2025
You’re Invited to Stop by KRYTAR Booth 1635 during IMS2025
ABOUT
Harvest and Collection
Harvest and collection is the process used to retrieve biological agents and vaccines present in cell cultures or to harvest and collect stem cells from blood or bone marrow. Many bioresearch companies have sophisticated systems for harvesting and collecting cells. These systems make counting cells easier and they also protect against contamination.
Cells are harvested once the cells reach a density level in the cell culture medium that precludes further growth. The best time to harvest cells is when they are in a confluent state (at least 50% of the culture dish is covered and before 100% of the dish is covered).
Cells can be harvested using on of three methods: Mechanical, using Proteolytic enzymes, or using EDTA. Mechanical harvesting uses a rubber spatula to remove the cells from the growth surface or culture. This method is quick but can cause many cells to die because it is highly disruptive. This method is favored when harvesting lots of different samples of cells to prepare extracts.
In this case, viability of the cells doesn’t matter. Three enzymes; Trypsin, Collagenase, and Pronase can be used in combination with EDTA. The combination of these enzymes with the EDTA makes cells detach from the growth medium.
This method is easy but also has a downside. It can damage the cell surface by eating up exposed cell surface proteins. EDTA can be used alone to detach cells from their medium and it is gentler than using trypsin.
Normally, collected cells are placed in a new suspension, or growth medium to continue growing new cultures. This is referred to as passaging or splitting the cells.