Harvest & Collection
PRODUCTS
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![Scientist-with-tablet-GettyImages-950594528]( "Unlocking Pharmaceutical Success: From Idea To Reality")
In the pharmaceutical industry, every capsule and tablet begins with a concept. Transforming that idea into a tangible product requires an expert manufacturing partner. Natoli stands out as a leader in pharmaceutical equipment and services, providing a comprehensive journey from formulation to full-scale production.
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![Koerber - Franz Ziel]( "Pharmaceutical Isolator Glove Testing System (GTS) For Annex 1 Compliance")
The Isolator Glove Testing System enables for Annex 1 compliant wireless and tubeless leak testing of gloves installed in Isolators or RABS. The GTS with the latest software technology offers an extremely flexible and fully integrable solution for glove testing as part of glove management.
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![GettyImages-2036497686-lab-team-collaboration-laboratory-tablet-computer]( "Avance Clinical's Specialist Areas Of Focus")
Avance Clinical offers deep scientific expertise and extensive knowledge across a range of specialized therapeutic indications, consistently achieving global regulatory approvals.
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![Chromatography GettyImages-1392302602]( "Process Development")
EirGenix is a contract development and manufacturing organization that performs high quality and cost-effective services supporting our clients in development, analytical testing, and GMP manufacturing of biopharmaceuticals from pre-clinical to commercial manufacturing
EirGenix has strong process development capabilities in both microbial and mammalian systems to provide our clients process development, process optimization, and process troubleshooting. We have successfully delivered results to meet clients’ requirement in product productivity, product quality, and process cost effectiveness. Our previous project experience includes recombinant proteins, plasmid DNA, fusion proteins, monoclonal antibodies, and biosimilars.
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![Marki - MMIQA-0626HPSM]( "Integrated Drive GaAs MMIC IQ Mixer: MMIQA-0626HPSM")
The MMIQA-0626HPSM is a broadband IQ mixer with an integrated broadband LO driver amplifier that is ideal for IQ, single sideband, and image reject mixing applications with wide bandwidths.
WHITE PAPERS AND CASE STUDIES
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![GettyImages-1372091146 patient ipad]( "Breaking Barriers In ED Treatment: A 100% Recruitment Success!")
Breaking Barriers In ED Treatment: A 100% Recruitment Success!Discover how Palleos achieved full patient enrollment across four countries in record time in an Erectile Dysfunction study.
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![GettyImages-1693748594 phone]( "Retention And Access In NSCLC Clinical Trials")
Retention And Access In NSCLC Clinical TrialsHelping participants navigate respiratory limitations, fatigue, and complex visit schedules in Non-Small Cell Lung Cancer (NSCLC) studies.
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![GettyImages-2103894533 office, team, coworkers, meeting]( "Accelerating Early Phase Oncology Study Development")
Accelerating Early Phase Oncology Study DevelopmentExplore a close collaboration to co-develop a comprehensive, adaptive protocol designed to support key decisions across multiple trial phases for an innovative cancer therapy.
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![GettyImages-2230550003 antibody receptor]( "High Drug Tolerance ADA Testing For Long‑Acting mAbs")
High Drug Tolerance ADA Testing For Long‑Acting mAbsSee how advanced ADA assay design overcomes extreme drug interference, enabling reliable immunogenicity assessment for long‑acting, high‑dose monoclonal antibodies in early clinical development.
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![GettyImages-538088463-scientist-cleaning-maintenance-bioreactor]( "How Bend Bioscience Standardized Operations And Boosted Compliance")
How Bend Bioscience Standardized Operations And Boosted ComplianceDiscover how Bend Bioscience replaced its outdated CMMS with RAM to achieve rapid compliance, boost efficiency across facilities, and cut operational costs by 25%.
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![240327_BMJ1L8A6473]( "Leveraging Single-Use Solutions To Solve Working Cell Bank Challenges")
Leveraging Single-Use Solutions To Solve Working Cell Bank ChallengesDiscover how custom manifolds enhance allogeneic therapy development from formulation to commercialization by improving process control, scalability, and efficiency.
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![GettyImages-1971327276 doctor patient]( "Ergomed's Solutions To The Challenges of Oncology Trials")
Ergomed's Solutions To The Challenges of Oncology TrialsExplore a pivotal Phase III global clinical trial investigating neoadjuvant immunotherapy for locally advanced squamous cell carcinoma of the head and neck (LA SCCHN).
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![120985056-gavins-point-dam]( "Aquatic Invasive Species Control At Gavins Point Dam")
Aquatic Invasive Species Control At Gavins Point DamIn this case study, read about how the US Army Corp of Engineers installed Hydro-Optic UV systems at Gavins Point Dam to protect turbines from invasive species. The system uses UV light to disinfect and has a TIR-based design for increased effectiveness.
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![GettyImages-1439780284 (1) milk bottling]( "Pasteurized Equivalent Water For AgriMark-Cabot Dairy In Vermont")
Pasteurized Equivalent Water For AgriMark-Cabot Dairy In VermontDiscover how AgriMark-Cabot Dairy transformed wastewater into a valuable resource using UV technology, achieving significant energy and water savings while maintaining stringent food safety standards.
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![GettyImages-184960936 fayetteville]( "The City Of Fayetteville's Flood Resiliency In The Face Of Climate Change: Mapping 15 Watersheds")
The City Of Fayetteville's Flood Resiliency In The Face Of Climate Change: Mapping 15 WatershedsThe city of Fayetteville, North Carolina has always had flooding issues, but it’s been getting worse as weather patterns have been changing. They were hit four years in a row by storms Matthew (2016), Irma (2017), Florence (2018), and Dorian (2019).
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![biologic-medicine-research-GettyImages-1413606459]( "Tracing PS80: How LC‑MS Resolved A Potency Discrepancy")
Tracing PS80: How LC‑MS Resolved A Potency DiscrepancyA targeted LC–MS investigation identifies molecular changes behind potency discrepancies, enabling accurate root‑cause analysis and stronger control of monoclonal antibody product quality.
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![Nova Benchtop]( "Transferring From Microfluidics To A Turbulent Mixer")
Transferring From Microfluidics To A Turbulent MixerWhat solutions did the client featured in this case study find when they sought help in transferring their formulation process to a turbulent Impinged Jet Mixing (IJM)?
NEWS
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Quantum Biopharma Announces Signing Of An Agreement With A Global Pharmaceutical Contract Research Organization To Prepare An IND (Investigational New Drug) Application Package For Lucid-21-302 (Lucid-MS), A First-In-Class Treatment For Multiple Sclerosis5/20/2025
Quantum BioPharma Ltd. (NASDAQ: QNTM) (CSE: QNTM) (FRA: 0K91) (“Quantum BioPharma” or the “Company”), a biopharmaceutical company dedicated to building a portfolio of innovative assets and biotech solutions, today announces that it has signed an agreement with a global pharmaceutical contract research organization to prepare an IND (Investigational New Drug) application package for Lucid-21-302 (Lucid-MS) with the US FDA.
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Brown Astronomers Create New Technique To Eliminate Signals Disrupting Sensitive Radio Telescopes2/12/2025
Astronomers sifting through data from the Murchison Widefield Array, a radio telescope in Western Australia, found themselves confronting an unexpected mystery.
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Stoichiometric Crystal Shows Promise In Quantum Memory7/7/2025
For over two decades, physicists have been working toward implementing quantum light storage—also known as quantum memory—in various matter systems.
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Pocket Alarm Detects And Records RF/Microwave Directed Energy Weapons, Nuclear Events, And Terrestrial Gamma Bursts5/8/2025
Ultraview Corp’s EM/GAMMALERT is a new pocket device that warns of RF/microwave jammer and directed energy weapon deployment1 - an emerging threat speculated as a modality in “Havana Syndrome”.
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How Lakes Connect To Groundwater Critical For Resilience To Climate Change7/9/2025
The study drew on data from 350 lakes across 18 European countries, collected between 2022 and 2024, to provide a comprehensive picture of how the continent’s lakes are coping with climate change.
ABOUT
Harvest and Collection
Harvest and collection is the process used to retrieve biological agents and vaccines present in cell cultures or to harvest and collect stem cells from blood or bone marrow. Many bioresearch companies have sophisticated systems for harvesting and collecting cells. These systems make counting cells easier and they also protect against contamination.
Cells are harvested once the cells reach a density level in the cell culture medium that precludes further growth. The best time to harvest cells is when they are in a confluent state (at least 50% of the culture dish is covered and before 100% of the dish is covered).
Cells can be harvested using on of three methods: Mechanical, using Proteolytic enzymes, or using EDTA. Mechanical harvesting uses a rubber spatula to remove the cells from the growth surface or culture. This method is quick but can cause many cells to die because it is highly disruptive. This method is favored when harvesting lots of different samples of cells to prepare extracts.
In this case, viability of the cells doesn’t matter. Three enzymes; Trypsin, Collagenase, and Pronase can be used in combination with EDTA. The combination of these enzymes with the EDTA makes cells detach from the growth medium.
This method is easy but also has a downside. It can damage the cell surface by eating up exposed cell surface proteins. EDTA can be used alone to detach cells from their medium and it is gentler than using trypsin.
Normally, collected cells are placed in a new suspension, or growth medium to continue growing new cultures. This is referred to as passaging or splitting the cells.