Harvest & Collection
PRODUCTS
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Polyzen is a single-source provider of polymer bags, bladders, and membranes for diverse applications in the medical industry. Our in-house polymer development, film extrusion, thermoforming, and welding capabilities allow us to manage any project from concept to prototype, production, validation, and beyond. Our goal is to be the trusted one-stop source for premium quality medical bags, bladders, and membranes, delivering unmatched reliability and outstanding customer service.
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The HLM-40ABH is a high-power, wideband signal limiter designed for protection and performance in RF systems operating from DC up to 40 GHz.
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The AMP20162 solid state high-power amplifier is designed for EMI/RFI testing, laboratory use, and general communication applications.
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Optimize single-use solutions for cryopreservation by engaging in studies that focus on specific timepoints and conditions pertaining to therapy storage, containment/protection, and transportation.
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The Sensors Unlimited 1280JSX-10µm VIS/SWIR digital video camera, developed by Raytheon’s RTX Business unit, is a next-generation high-definition imaging solution optimized for covert surveillance and low-light applications.
WHITE PAPERS AND CASE STUDIES
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Minimizing Water Outages With Targeted Valve Control
The Town of Holly Springs, NC, used Hydra-Stop's Insta-Valve 250 insertion valves to repair a leak in a transmission line without causing water service outages to over 40 residences. This solution saved the town from widespread outages and other costs associated with a system shutdown.
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Driving Early-Phase Success In Advanced Solid Tumors Study
A European biotech company collaborated with TFS HealthScience to conduct an early-phase clinical trial focusing on advanced and metastatic solid tumors.
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Vaccine Trial Sees >90% eCOA Adherence
Discover how we addressed vaccine trial challenges and drove remarkable success, achieving over 90% adherence to eCOA, ensuring active engagement from the trial participants, and yielding consistent, reliable trial data.
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Container Selection For A Highly Sensitive Drug Product: A Success Story
Learn about the importance of selecting the right container for sensitive drug products and how close collaboration is crucial for avoiding commercialization delays and safety risks to patients.
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Transforming Clinical Supply Planning From Spreadsheets To Smart Forecasting
Streamline your clinical supply forecasting and reduce risk by moving beyond manual spreadsheets to an integrated, real-time supply management solution.
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Enhancing Clinical Supply Chain With Signant SmartSignals Supplies
A global pharma leader improved supply chain efficiency and compliance by digitalizing processes with Signant's SmartSignals Supplies, achieving better visibility, traceability, and reduced errors.
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Mining Use Case: Nelson Tunnel Superfund Site, Creede, Colorado
Advanced electrocoagulation offers a compact, chemical-free solution for treating acidic mine water. By effectively removing heavy metals and naturally balancing pH, this mobile technology ensures safe environmental discharge while minimizing waste volume and operational footprints in rugged, remote locations.
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Groundwater DWTP (NJ) – DEXSORB Full-Scale
Cyclopure was invited to replace ion exchange resin to remove PFAS from groundwater at a groundwater pump station, located in New Jersey. The decision to replace IXR was due to poor PFAS removal caused by manganese fouling.
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Innovating The mAb Characterization Process
Understanding the characteristics of a molecule's "personality" is crucial for optimizing development and manufacturing. Learn how to overcome the challenges in the characterization process.
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Minimizing Disruption And Maximizing Continuity During An Emergency Valve Installation
Discover how a municipal utility executed an urgent emergency repair on an active 12-inch main in under three hours, entirely eliminating the need for neighborhood boil advisories or disruptive commercial shutdowns.
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AMERICAN SpiralWeld Pipe Performs In New Music City Stadium Project
Read about a project at the Nissan Stadium in Nashville, TN, that involved SpiralWeld Pipe.
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Partnership Driving Superior Enrollment And Speed In Phase III Trial
Examine the partnership between CRIO and Sitero, including how it underscores the significant impact of technology in optimizing trial performance and accelerating treatment development.
NEWS
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Spearhead Bio Awarded NSF Tech Transfer Grant To Accelerate Development Of Improved Corn Varieties7/14/2025
Spearhead Bio, a biotechnology startup revolutionizing crop genome engineering through the use of plants' own natural DNA, has been awarded a Small Business Technology Transfer (STTR) Phase I grant from the U.S. National Science Foundation (NSF).
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Xscape Photonics And Tower Semiconductor Unveil The Industry's First Optically Pumped On-Chip Multi-Wavelength Laser Platform For AI Datacenter Fabrics8/25/2025
Tower Semiconductor (NASDAQ/TASE: TSEM), a leading foundry of high-value analog semiconductor solutions, and Xscape Photonics, a U.S.-based innovator in advanced photonic interconnects funded by industry leaders such as NVIDIA and Cisco, today announced the successful prototyping and validation kit availability of the industry’s first on-chip, optically pumped, multi-wavelength laser source
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Kontron Introduces The New AL I.MX8M Mini LTE: IoT Gateway With LTE Cat1 Module5/6/2025
Kontron, a leading global supplier of IoT/Embedded Computer Technology (ECT), is expanding its automation line with the AL i.MX8M Mini LTE model.
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Almost 49M Tons Of Manure Pose Health Risk For Minnesota's Water5/15/2025
Huge amounts of manure from massive livestock facilities in Minnesota could pollute drinking and recreational water throughout the state, posing a significant health risk.
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Repligen Corporation & Univercells Technologies Partner TO Enable Real-Time Monitoring OF Viral Vector And Vaccine Biomanufacturing7/9/2025
Univercells Technologies, a Donaldson Life Sciences business and global provider of bioprocessing solutions, announced a collaboration with Repligen Corporation to integrate real-time monitoring capabilities and enhance the development and manufacturing of viral vectors and vaccines.
ABOUT
Harvest and Collection
Harvest and collection is the process used to retrieve biological agents and vaccines present in cell cultures or to harvest and collect stem cells from blood or bone marrow. Many bioresearch companies have sophisticated systems for harvesting and collecting cells. These systems make counting cells easier and they also protect against contamination.
Cells are harvested once the cells reach a density level in the cell culture medium that precludes further growth. The best time to harvest cells is when they are in a confluent state (at least 50% of the culture dish is covered and before 100% of the dish is covered).
Cells can be harvested using on of three methods: Mechanical, using Proteolytic enzymes, or using EDTA. Mechanical harvesting uses a rubber spatula to remove the cells from the growth surface or culture. This method is quick but can cause many cells to die because it is highly disruptive. This method is favored when harvesting lots of different samples of cells to prepare extracts.
In this case, viability of the cells doesn’t matter. Three enzymes; Trypsin, Collagenase, and Pronase can be used in combination with EDTA. The combination of these enzymes with the EDTA makes cells detach from the growth medium.
This method is easy but also has a downside. It can damage the cell surface by eating up exposed cell surface proteins. EDTA can be used alone to detach cells from their medium and it is gentler than using trypsin.
Normally, collected cells are placed in a new suspension, or growth medium to continue growing new cultures. This is referred to as passaging or splitting the cells.