Harvest & Collection
PRODUCTS
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Autodesk® Info360® Plant is a cloud-based operational analytics solution within the Info360 platform designed specifically for water and wastewater treatment plants to improve real-time data analysis and enable workflows associated with performance, compliance, and improvement planning.
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The AMP50006 is a high-performance solid state pulse amplifier engineered for demanding X-Band applications requiring high output power, ruggedness, and reliability.
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The Empower RF Model 2240 is engineered for robust pulse and continuous-wave (CW) applications within the C-band frequency range and efficiency in a compact 3RU form factor.
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Protect your pharmaceutical products from any potential damage during their line transit. Integrate nests or trays into your line transport processes with our flexible, customizable options.
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The MA9905 is an X-band receiver protector with an integral noise source. This receiver protector operates at 2.5 kW, and features a compact size for applications requiring less space.
WHITE PAPERS AND CASE STUDIES
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Forge Boosts Efficiency And Compliance During External Collaboration
Streamlined collaboration and unified quality systems are helping CDMOs cut review times. Discover how connected workflows improve compliance and efficiency for faster delivery of life-changing treatments.
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How Sharp Packaging's Clinical Packaging Process Is 30% Faster
Discover how digitized workflows and real-time verification are helping streamline clinical trial packaging, reduce complexity, and improve quality in a high-stakes, time-sensitive environment.
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A Proactive Approach To Service Line Inventory
In this case study, learn how Silver Creek Water Corporation successfully created a lead service line inventory with the help of 120Water. They have only 7 unknown service lines left out of 7,000 and plan to eliminate them through a resident survey.
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Case Study: ThioBridge™ Conjugates
Discover how Abzena’s ThioBridge™ technology is enabling the next generation of stable, scalable, and clinically advanced ADCs through site-specific conjugation.
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Building A Scalable Oncology Engine In A Dynamic Market
Learn how a top-10 global pharmaceutical company partnered with Medable to rapidly scale the number of oncology trials it could concurrently conduct.
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Delivering A Registrational GI Trial Through Ongoing Protocol Shifts
A biotech developing bispecific antibodies partnered with a flexible CRO to launch its first U.S. GI oncology trial, requiring strategic insight and full-service clinical support.
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ProPharma Supports A Contract Manufacturer's Form 483 Response
Learn how a small contract manufacturer navigated a complex FDA 483 Observation notice and implemented effective remediation strategies that addressed multiple system-wide concerns.
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Restarting A Manufacturing Campus And Revitalizing A Community
A high‑risk facility acquisition in Huntsville became a blueprint for revitalizing a modern pharmaceutical campus. Discover how coordinated action turned a massive shutdown into a renewed manufacturing hub.
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How A Top Biotech Achieved Right-First-Time Batches
Gain insight into how a global leader in pharmaceutical manufacturing overcame significant challenges related to their ultrafiltration process.
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Tailored ISO 5 RABs Unit To Protect AST's Patented Filling Machine
Uncover how AST's satisfaction with Germfree's solution led to the acquisition of two additional units, showcasing the project's success and Germfree's expertise in tailored cleanroom solutions.
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RWD's Significance In The Largest FDA-Funded IOL Study Of Pediatric Patients
With FDA grant support, the American Academy of Ophthalmology and Verana Health conducted the largest real-world study to date on intraocular lens (IOL) use in pediatric cataract patients.
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Comparative Analysis Of Batch And Continuous Processes
Explore a comparative analysis that showcases the superior performance of continuous processing over traditional batch methods, highlighting key improvements in efficiency and environmental impact.
NEWS
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Aircraft Toilets Could Flush Out Spread Of Global Superbugs8/18/2025
Wastewater from aircraft toilets could provide a critical warning system for the global spread of antimicrobial resistant (AMR) superbugs, a silent pandemic that threatens to kill more people than cancer by 2050.
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Agilitas Energy Expands Into Hydropower With Acquisition Of Two Projects In West Virginia And Maryland6/24/2025
Agilitas Energy, a leading developer and operator of renewable energy and energy storage systems, today announced the acquisition of two late-stage hydropower development projects from Advanced Hydro Solutions.
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ZEISS Introduces The New Smartzoom 100: The Future Of Digital Microscopy For Efficient Optical Inspections5/6/2025
ZEISS presents the new ZEISS Smartzoom 100, an innovative digital microscope for fast and efficient quality assurance.
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Evonik Partners With ST Pharm To Increase Its Offerings For RNA And Nucleic Acid Delivery1/8/2025
Evonik is partnering with ST Pharm, a company that manufactures active ingredients for gene therapy, to expand its RNA and nucleic acid therapeutic services.
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University Of St. Thomas Offers No-Cost Machining And CNC Optimization Training7/18/2025
The University of St. Thomas is launching a new, no-cost training program to help manufacturing professionals, engineers, and students upskill and gain valuable insights into using computer simulations to optimize CNC machining.
ABOUT
Harvest and Collection
Harvest and collection is the process used to retrieve biological agents and vaccines present in cell cultures or to harvest and collect stem cells from blood or bone marrow. Many bioresearch companies have sophisticated systems for harvesting and collecting cells. These systems make counting cells easier and they also protect against contamination.
Cells are harvested once the cells reach a density level in the cell culture medium that precludes further growth. The best time to harvest cells is when they are in a confluent state (at least 50% of the culture dish is covered and before 100% of the dish is covered).
Cells can be harvested using on of three methods: Mechanical, using Proteolytic enzymes, or using EDTA. Mechanical harvesting uses a rubber spatula to remove the cells from the growth surface or culture. This method is quick but can cause many cells to die because it is highly disruptive. This method is favored when harvesting lots of different samples of cells to prepare extracts.
In this case, viability of the cells doesn’t matter. Three enzymes; Trypsin, Collagenase, and Pronase can be used in combination with EDTA. The combination of these enzymes with the EDTA makes cells detach from the growth medium.
This method is easy but also has a downside. It can damage the cell surface by eating up exposed cell surface proteins. EDTA can be used alone to detach cells from their medium and it is gentler than using trypsin.
Normally, collected cells are placed in a new suspension, or growth medium to continue growing new cultures. This is referred to as passaging or splitting the cells.