Harvest & Collection
PRODUCTS
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Learn how robust in-house analytical services and protein characterization are crucial for successful development and manufacturing programs.
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Accelerate your drug development with our comprehensive pre-formulation, formulation, and novel delivery system expertise, tailored to optimize physical form, enhance solubility, and support scale-up.
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The Natoli NCF-45 Capsule Filling Machine offers unmatched speed, precision, and versatility for efficient powder and pellet encapsulation, maximizing your production output and minimizing waste.
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Fast-track your market entry with our robust aseptic filling platform. The Flex-Line™ Robotic Filler provides full integration of Scientific Products filling and Comecer isolation technologies for a seamless process from order through Validation.
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The AMP30008 is a rugged, compact, and lightweight solid state high power pulse amplifier designed for demanding L-Band radar applications.
WHITE PAPERS AND CASE STUDIES
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Collaborate With Sponsors, Ensure Compliance, And Secure Product Quality
A top 5 global CDMO implemented cloud-based IDBS PIMS for improved manufacturing data collection and information visibility for real-time decision-making.
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Modernizing Operational Maintenance At Treatment Plants
In 2017, the Harford County Division of Water and Sewer began looking for a modern work management solution to help automate preventive maintenance, coordinate work activities between groups, manage material inventories, and capture important data.
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Scalable FSP Model For Managing IVD Clinical Trials In A Niche Market
Here, we illustrate the advantages of our FSP services, including enhanced scalability, risk mitigation, cost efficiency, and timely project completion.
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How Sharp Packaging's Clinical Packaging Process Is 30% Faster
Discover how digitized workflows and real-time verification are helping streamline clinical trial packaging, reduce complexity, and improve quality in a high-stakes, time-sensitive environment.
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Improve Operational Efficiency And Capital Improvement Program Management
The City of Grand Rapids, MI sought out a partner to take responsibility for the operation and maintenance of the monitoring network including hardware, software, and data preparation.
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U.S. Renal Care Achieves 75% Site Adoption Of eConsent
By dispelling prevalent misconceptions regarding participant age, cost, and complexity, see how this platform emerged as a versatile, rapid, and effective solution tailored to the unique needs of the elderly renal care population.
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Early-Stage Development In Rare Pediatric Oncology
Learn about the strategic approach a biotechnology company utilized to address significant hurdles in launching a Phase 1 clinical trial for a novel therapy targeting a rare pediatric cancer.
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Lead Identification And Optimization For Computational Drug Discovery
AI-generated Fab molecules promise speed, but can computational designs actually express and bind at scale? A high-throughput screening workflow offers a data-backed answer.
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Ensuring Reliability And Patient Safety With XiltriX
Protect the integrity of your therapies and ensure patient safety by investing in reliable, real-time environmental monitoring systems that proactively address operational vulnerabilities.
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Scaling Success: A Blueprint For Flexible Biometrics Partnerships
Learn how a micro-FSP model and integrated biometrics team can scale from specialized support to a full-service solution, ensuring agility and consistency as clinical trial needs evolve.
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Enhancing Novel Developability Through Automated MS Analytics
Growing biotherapeutic complexity demands MS workflows that can unify diverse datasets. Learn how automated approaches enhance data quality, streamline analysis, and support faster development.
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Access And Retention In Metastatic Colorectal Cancer Trials
Making it easier for participants in metastatic colorectal cancer trials to reach specialized sites and stay on schedule with managed travel, lodging, and reimbursements
NEWS
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GD Energy Products' Y-Shaped Drilling Module Now Rated For 10,000 PSI8/18/2025
GD Energy Products (GDEP), the leading total solutions provider for the frac, drilling and well servicing pumps market, has announced its patented Y-Shaped Drilling Module is now rated for operating pressures up to 10,000 psi.
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Masdar And Iberdrola Announce €5.2B UK Offshore Wind Deal And Full Energization Of 476MW German Offshore Wind Farm7/10/2025
Masdar, a global clean energy leader, and Iberdrola, one of the world’s largest energy companies, have reached two major milestones with a €5.2B co-investment in the UK’s East Anglia THREE offshore wind farm – the largest offshore wind transaction of the decade – and the full energization of their 476MW Baltic Eagle project in Germany.
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U.S. Department Of Energy Announces $6.9M In Projects To Support Effective Community Waste-To-Energy Strategies For Local Transportation Needs1/7/2025
The U.S. Department of Energy's (DOE) Bioenergy Technologies Office (BETO) and Vehicle Technologies Office (VTO) announced $6.9M in funding for nine projects to support local waste-to-energy management solutions for transportation energy needs.
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Drawing Inspiration From Ancient Chemical Reactions3/20/2025
To help find solutions to the planet’s climate crisis, MIT Associate Professor Daniel Suess is looking to Earth’s ancient past.
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New Land Grant Research Detects Dicamba Damage From The Sky7/9/2025
Drones can now detect subtle soybean canopy damage from dicamba at one ten-thousandth of the herbicide’s label rate — simulating vapor drift — eight days after application.
ABOUT
Harvest and Collection
Harvest and collection is the process used to retrieve biological agents and vaccines present in cell cultures or to harvest and collect stem cells from blood or bone marrow. Many bioresearch companies have sophisticated systems for harvesting and collecting cells. These systems make counting cells easier and they also protect against contamination.
Cells are harvested once the cells reach a density level in the cell culture medium that precludes further growth. The best time to harvest cells is when they are in a confluent state (at least 50% of the culture dish is covered and before 100% of the dish is covered).
Cells can be harvested using on of three methods: Mechanical, using Proteolytic enzymes, or using EDTA. Mechanical harvesting uses a rubber spatula to remove the cells from the growth surface or culture. This method is quick but can cause many cells to die because it is highly disruptive. This method is favored when harvesting lots of different samples of cells to prepare extracts.
In this case, viability of the cells doesn’t matter. Three enzymes; Trypsin, Collagenase, and Pronase can be used in combination with EDTA. The combination of these enzymes with the EDTA makes cells detach from the growth medium.
This method is easy but also has a downside. It can damage the cell surface by eating up exposed cell surface proteins. EDTA can be used alone to detach cells from their medium and it is gentler than using trypsin.
Normally, collected cells are placed in a new suspension, or growth medium to continue growing new cultures. This is referred to as passaging or splitting the cells.