Harvest & Collection
PRODUCTS
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![e-Builder-Screenshot_Water-Online-450x300_42224]( "Trimble e-Builder")
As the industry’s most advanced digital construction management system, Trimble e-Builder enables efficiencies across the entire design-build lifecycle, with a smooth transition to the operation phase. Reduce risk, enhance collaboration and improve outcomes using the industry-leading digital project delivery software for owners.
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![GettyImages-1175279159 powder]( "Onsite Preclinical Services To Support Your Product Development: Powder Micromeritics")
Understanding the fine details of powder properties is crucial in the pharmaceutical industry, where the behavior of particulate matter can affect manufacturability and the efficacy of the final product.
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![HPLC Chromatography laboratory scientist GettyImages-1309780330]( "Analytical & Quality Control")
Learn how robust in-house analytical services and protein characterization are crucial for successful development and manufacturing programs.
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![GettyImages-1327977866-cell-culture-sample-laboratory]( "Development Solutions For Biologics CHO CLD Platforms")
Aragen offers choice of CLD platforms, efficient Upstream and Downstream process development
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![Purolite-3673 (2)]( "Chromatography Masterclass")
WHITE PAPERS AND CASE STUDIES
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![GettyImages-1272298861 digital transformation]( "Digital Transformation - The Power Of Your Data")
Digital Transformation - The Power Of Your DataDiscover how you can circumvent numerous recirculations during the ultrafiltration process step, boost downstream bioprocess yield, and identify and resolve process inefficiencies.
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![GettyImages-1296415689 trial diversity]( "Drilling Down On Diversity And Feasibility")
Drilling Down On Diversity And FeasibilityA mid-sized contract research organization (CRO) sought help with writing clinical trial diversity action plans and assessing feasibility for therapeutic areas outside its usual scope.
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![GettyImages-157291618 Scientist inspecting vial]( "Leveraging High-Pressure Sterile Filtration For Highly Viscous Solutions")
Leveraging High-Pressure Sterile Filtration For Highly Viscous SolutionsThis research demonstrates the potential of high-pressure sterile filtration to enhance efficiency, reduce waste, and accelerate the development of innovative therapies.
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![GettyImages-1422488606]( "Working Smarter: Empowering Water Operators With Integrated Data")
Working Smarter: Empowering Water Operators With Integrated DataAs water utilities face the challenges of sustainability, efficiency, and service quality, digital technology has become a necessity. The right tech can help deliver reliable service, optimize systems, and meet sustainability goals, but integrating the data streams these solutions generate can offer even greater gains – allowing utilities to move faster and achieve more powerful outcomes.
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![energy flow, data transmission, technological connectivity-GettyImages-2240709017]( "How Smart Process Automation Cut Wastewater Chemical Costs By $75,000 Annually")
How Smart Process Automation Cut Wastewater Chemical Costs By $75,000 AnnuallyDiscover how a major wastewater utility transitioned from manual, static dosing to real-time, autonomous optimization software, stabilizing hydrogen sulfide scrubber efficiency above critical targets while slashing chemical operating costs by twenty-five percent.
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![GettyImages-1819626829 patient recruitment]( "A Community-Focused Approach To Metabolic Disease Trials")
A Community-Focused Approach To Metabolic Disease TrialsLearn how innovative strategies like free health exams, community engagement, and a comprehensive patient database helped this project achieve rapid enrollment with a high level of patient diversity.
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![chennai-india]( "Disinfection For Drinking Water Plant In Chennai, India")
Disinfection For Drinking Water Plant In Chennai, IndiaThe Chennai Metropolitan Water Supply and Sewerage Board (CMWSSB) encountered significant challenges in treating high algae loads at its drinking water plant, which processes 1.5 million liters of water daily. The primary issue arose from the organic load in lake water, which, when treated with conventional chlorine disinfectants, resulted in harmful disinfection byproducts (DBPs).
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![Laminar Flow Glovebox Isolator LFGI]( "CAR-T And Laminar Flow Glovebox Isolators")
CAR-T And Laminar Flow Glovebox IsolatorsA request was made for a containment system that would protect operators during lentivirus transfer, as well as provide a controlled environment for IL-2 charging of media, bead addition, and blood bag spiking.
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![dunea]( "Collaborative Tech: How Dunea Is Boosting Network Visibility And Resilience")
Collaborative Tech: How Dunea Is Boosting Network Visibility And ResilienceIntegrating high-frequency sensor data with digital twins enhances network visibility and accelerates response times. This collaborative approach allows utilities to detect anomalies instantly, optimize maintenance, and simulate operational scenarios to ensure long-term system resilience.
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![GettyImages- severn trent]( "Severn Trent Exceeds Leak Reduction Targets With Innovative Itron Water Solutions")
Severn Trent Exceeds Leak Reduction Targets With Innovative Itron Water SolutionsSevern Trent’s smart metering program, powered by Itron’s technology, is transforming water conservation—reducing leaks by 6 million liters, cutting costs, and empowering customers to use water more wisely.
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![AquaNereda system at Wolcott WWTP]( "AquaNereda Provides The Lowest Total Cost Of Ownership For 10x Capacity Increase And Nutrient Removal Limits")
AquaNereda Provides The Lowest Total Cost Of Ownership For 10x Capacity Increase And Nutrient Removal LimitsThe Wolcott Wastewater Treatment Plant in Kansas City chose the AquaNereda technology for its capacity and cost benefits. The system improved nutrient removal and met permit requirements.
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![1500368452-molecule]( "ArxZyme™ Acetone Removal For AMPAC Fine Chemicals")
ArxZyme™ Acetone Removal For AMPAC Fine ChemicalsAMPAC faced a critical challenge with acetone management. The high acetone levels in the effluent from its chemical processing operations required an effective industrial wastewater treatment solution to meet environmental regulations and ensure safe discharge.
NEWS
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ROO.AI Adds Automated Warranty Management To Help Businesses Reduce Maintenance Costs5/27/2025
ROO.AI announced today the availability of a new connected worker platform module for Warranty Management to simplify the process of identifying repairs under warranty and recovering warranty repair costs.
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Sticking To Innovation: The Surprising Role Of Tape In terahertz Photonics8/20/2025
Could the key to next-generation photonic devices be hiding in your drawer? For Professor Jean-Michel Ménard, an ordinary roll of tape proved essential in building groundbreaking terahertz filters that are set to transform wireless tech, imaging and diagnostics.
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Kontron Introduces The New AL I.MX8M Mini LTE: IoT Gateway With LTE Cat1 Module5/6/2025
Kontron, a leading global supplier of IoT/Embedded Computer Technology (ECT), is expanding its automation line with the AL i.MX8M Mini LTE model.
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Rohde & Schwarz Hosts RF Testing Innovations Forum 2025, Helping Design Engineers Elevate Their RF Expertise5/6/2025
Taking place over two days, Rohde & Schwarz and industry partners will be providing a virtual platform for RF design engineers to enhance their RF expertise and engage with industry leaders at the forefront of innovation.
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Repligen Corporation & Univercells Technologies Partner TO Enable Real-Time Monitoring OF Viral Vector And Vaccine Biomanufacturing7/9/2025
Univercells Technologies, a Donaldson Life Sciences business and global provider of bioprocessing solutions, announced a collaboration with Repligen Corporation to integrate real-time monitoring capabilities and enhance the development and manufacturing of viral vectors and vaccines.
ABOUT
Harvest and Collection
Harvest and collection is the process used to retrieve biological agents and vaccines present in cell cultures or to harvest and collect stem cells from blood or bone marrow. Many bioresearch companies have sophisticated systems for harvesting and collecting cells. These systems make counting cells easier and they also protect against contamination.
Cells are harvested once the cells reach a density level in the cell culture medium that precludes further growth. The best time to harvest cells is when they are in a confluent state (at least 50% of the culture dish is covered and before 100% of the dish is covered).
Cells can be harvested using on of three methods: Mechanical, using Proteolytic enzymes, or using EDTA. Mechanical harvesting uses a rubber spatula to remove the cells from the growth surface or culture. This method is quick but can cause many cells to die because it is highly disruptive. This method is favored when harvesting lots of different samples of cells to prepare extracts.
In this case, viability of the cells doesn’t matter. Three enzymes; Trypsin, Collagenase, and Pronase can be used in combination with EDTA. The combination of these enzymes with the EDTA makes cells detach from the growth medium.
This method is easy but also has a downside. It can damage the cell surface by eating up exposed cell surface proteins. EDTA can be used alone to detach cells from their medium and it is gentler than using trypsin.
Normally, collected cells are placed in a new suspension, or growth medium to continue growing new cultures. This is referred to as passaging or splitting the cells.