Harvest & Collection
PRODUCTS
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Eurofins PSS Insourcing Solutions® (PSS) is a global, award-winning managed service provider that places our people at your site dedicated to running and managing your manufacturing and laboratory services while eliminating headcount, co-employment and project-management worries.
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Free your safety and clinical teams to focus on what matters most.
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At Mikart, our mission is to leverage our technical expertise in pharmaceutical development and manufacturing to deliver services that meet the diverse needs of our customers.
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In today’s complex clinical research landscape, sponsors and CROs face numerous challenges that can impact study timelines, costs, and data quality. The iMednet platform offers innovative solutions to address these critical issues.
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Geospace Technologies offers a complete line of AMI water meter connector cables specifically designed and manufactured to meet the rugged requirements for in-pit, underwater applications. Geospace’s unique design ensures total moisture sealing for even the toughest underwater environments, yet they are easily re-entered for troubleshooting a transponder or for a meter swap-out. Versions are available that utilize molded-in-place or potted terminators for sealing. Either version is totally intermateable with the Itron Inline Connector.
WHITE PAPERS AND CASE STUDIES
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Bend Successfully Rescues Powder-Filled Capsule Program
Learn how to overcome tech transfer challenges and ensure consistent content uniformity by leveraging multidisciplinary expertise and decades of commercial encapsulation experience.
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Rapid Results In A High-Stakes Dry Eye Disease Trial
This time-sensitive Phase 3 trial in dry eye disease required precision project management leveraging strong site relationships, ophthalmology-specific expertise, and data-driven site selection.
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Navigating Regulatory Compliance: A Success Story In The Pharma Industry
Reveal how one pharmaceutical facility overcame strict cross-contamination rules and space limits without costly building modifications to ensure operational continuity.
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Expanding Accessibility In A Phase 3 Influenza Study Through Community-Based Research
By meeting participants where they are, this study sets a new benchmark for inclusive, efficient, and impactful vaccine development.
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Responsible Reclamation – City of Abilene, Texas
To combat drought, Abilene, Texas, implemented a reuse system utilizing O3 + BAC to remove trace organics. This solution met strict standards, ensured water resilience, and proved more cost-effective than AOP alternatives.
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Cell Line Development For High-Titer Lentivirus Vector Production
Explore a groundbreaking method to significantly enhance LV vector yield using engineered HEK293T cells. This approach paves the way for more efficient and large-scale production of LV vectors.
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Accelerating Early Phase Oncology Study Development
Explore a close collaboration to co-develop a comprehensive, adaptive protocol designed to support key decisions across multiple trial phases for an innovative cancer therapy.
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Electronic Batch Reporting
Learn how a CDMO automatically created a comprehensive batch report model to drive their reporting and speed root cause identification of quality failures with an Industrial DataOps software solution.
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Achieving A 2.67x Reduction In Study Build Time For An Innovative Neuromodulation Study
This study explores the potential of Focused Ultrasound Neuromodulation in deepening meditative states, and the platform that helps enhance the overall experience for researchers and participants alike.
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Manufacturing Transfers: Delivering 140+ Precision Medical Devices Without Missing A Deadline
Go inside a successful manufacturing transfer of over 140 Class-III silicone medical devices and on-time delivery for a top-30 OEM through expert project management and rigorous validation processes.
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Improving Pre-Clinical Study Efficiency With mRNA-LNP Technology
Uncover how Repair Biotechnologies, in collaboration with Vernal Biosciences, helped to pave the way for the next generation of breakthrough treatments for cholesterol and aging-related diseases.
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Executing Concurrent Decentralized RCTs And RWE At Scale
See how a team of four managed data for 40 peer-reviewed studies and 200,000 participants.
NEWS
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3-In-1 Orbital Thread Milling Cutters For New Thread Sizes1/14/2025
Following the successful introduction of the Thrill·tec TC645 Supreme orbital drill/thread mills for dimensions from M4 to M12 in 2023, Walter is now expanding its range to cover additional metric dimensions from M14 to M20 as well as their imperial equivalents.
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Fine-Tuning Zinc Supplementation, Light Exposure To Boost Microgreens' Nutrition8/26/2025
Microgreens, which are young, edible plants that only take one to three weeks to harvest, are more than garnish at trendy restaurants — they could be the answer to global hunger, according to plant scientists at Penn State.
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The Persistence Of PFAS - IDTechEx Covers Growing PFAS Regulations4/24/2025
Per- and polyfluoroalkyl substances (PFAS) are a broad group of chemicals that includes both polymers and non-polymers used in many applications, from transport to consumer products.
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PNE Group Receives Permits For Three New Wind Farms In Germany7/8/2025
In the second quarter of 2025, the PNE Group received the necessary permits for the construction and operation of three onshore wind farms in the German states of Brandenburg, Hesse, and North Rhine-Westphalia.
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University Of St. Thomas Offers No-Cost Machining And CNC Optimization Training7/18/2025
The University of St. Thomas is launching a new, no-cost training program to help manufacturing professionals, engineers, and students upskill and gain valuable insights into using computer simulations to optimize CNC machining.
ABOUT
Harvest and Collection
Harvest and collection is the process used to retrieve biological agents and vaccines present in cell cultures or to harvest and collect stem cells from blood or bone marrow. Many bioresearch companies have sophisticated systems for harvesting and collecting cells. These systems make counting cells easier and they also protect against contamination.
Cells are harvested once the cells reach a density level in the cell culture medium that precludes further growth. The best time to harvest cells is when they are in a confluent state (at least 50% of the culture dish is covered and before 100% of the dish is covered).
Cells can be harvested using on of three methods: Mechanical, using Proteolytic enzymes, or using EDTA. Mechanical harvesting uses a rubber spatula to remove the cells from the growth surface or culture. This method is quick but can cause many cells to die because it is highly disruptive. This method is favored when harvesting lots of different samples of cells to prepare extracts.
In this case, viability of the cells doesn’t matter. Three enzymes; Trypsin, Collagenase, and Pronase can be used in combination with EDTA. The combination of these enzymes with the EDTA makes cells detach from the growth medium.
This method is easy but also has a downside. It can damage the cell surface by eating up exposed cell surface proteins. EDTA can be used alone to detach cells from their medium and it is gentler than using trypsin.
Normally, collected cells are placed in a new suspension, or growth medium to continue growing new cultures. This is referred to as passaging or splitting the cells.