Harvest & Collection
PRODUCTS
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![GettyImages-1492337134 doctor notes]( "Clinical Operations And Project Management")
Consider the benefits of an integrated operations and project management approach across all phases and regions.
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![Hull i-Dositecno Nasal Spray Filling Machine]( "Pharmaceutical Nasal Spray Filling System")
For a nasal spray production fill-finish solution that offers unparalleled versatility, look no further! The Hull i-Dositecno BI and MI Nasal Spray Filling Machines simplify your manufacturing workflow to enable accurate and consistent rotary filling, stoppering and capping. With simple servo-driven motion-controlled design they can fill up to 50 or 200 units per minute (upm).
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![hydroconn]( "HYDROCONN® Series III")
Geospace Technologies offers a complete line of AMI water meter connector cables, specifically designed and manufactured to meet the rugged requirements for in-pit, underwater applications. Geospace’s unique design ensures total moisture sealing for even the toughest underwater environments, yet they are easily re-entered for troubleshooting a transponder or for a meter swap-out.
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![Syringes GettyImages-171324030]( "Plastic Syringe Assembly")
We cover the pre-assembly of a plastic syringe with cannula, as well as the final assembly of multi-component syringes (4-8 or 8-12 components).
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![GettyImages-1097562996-pill-tablet-capsule-OSD-oral-solid]( "Your Partner In Oral Dosage Development And Commercialization")
At Mikart, our mission is to leverage our technical expertise in pharmaceutical development and manufacturing to deliver services that meet the diverse needs of our customers.
WHITE PAPERS AND CASE STUDIES
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![Axine-electraCLEAR]( "Achieving Complete Destruction Of PFAS Using electraCLEAR Process")
Achieving Complete Destruction Of PFAS Using electraCLEAR ProcessIn early 2023, Lacks Enterprises Inc., a large automotive component supplier in the midwestern US, engaged Axine to address destruction of legacy PFAS compounds in wastewater from its manufacturing processes.
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![GettyImages-820772090 eyes]( "Global Start-Up For Multinational Geographic Atrophy Trial")
Global Start-Up For Multinational Geographic Atrophy TrialThis partnership allowed a leading biopharmaceutical company to navigate the complexities of a Phase IIb study investigating a novel pegylated RNA adapter for geographic atrophy secondary to dry AMD.
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![GettyImages-1357020474-digital-computer-icons-hands-business-working]( "MilliporeSigma's 97-Day Implementation Success Story")
MilliporeSigma's 97-Day Implementation Success StoryRead how MilliporeSigma transformed validation processes with a digital validation system to achieve compliance in just 97 days, as well as learn key takeaways from their swift transition.
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![120985056-gavins-point-dam]( "Aquatic Invasive Species Control At Gavins Point Dam")
Aquatic Invasive Species Control At Gavins Point DamIn this case study, read about how the US Army Corp of Engineers installed Hydro-Optic UV systems at Gavins Point Dam to protect turbines from invasive species. The system uses UV light to disinfect and has a TIR-based design for increased effectiveness.
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![Koerber - catalent]( "Why A Leading Manufacturing Partner Chose NeoTOP Packaging Machines")
Why A Leading Manufacturing Partner Chose NeoTOP Packaging MachinesLearn how a leading CDMO partnered with Körber to quickly deploy a high-speed packaging solution to meet tight production deadlines in the face of a global pandemic.
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![GettyImages-1439780284 (1) milk bottling]( "Pasteurized Equivalent Water For AgriMark-Cabot Dairy In Vermont")
Pasteurized Equivalent Water For AgriMark-Cabot Dairy In VermontDiscover how AgriMark-Cabot Dairy transformed wastewater into a valuable resource using UV technology, achieving significant energy and water savings while maintaining stringent food safety standards.
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![GettyImages-1131587509-syringe-vial-injection-inspection]( "Container Closure Integrity Test Method Development For Autoinjectors")
Container Closure Integrity Test Method Development For AutoinjectorsDiscover an autoinjector technology that leverages laser-based headspace analysis for container closure integrity to advance biologic drug delivery with precision, safety, and regulatory confidence.
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![socal-GACs]( "AqueoUS Vets Named A Manufacturing Partner For A Southern CA Water Treatment Facility")
AqueoUS Vets Named A Manufacturing Partner For A Southern CA Water Treatment FacilityIn August 2018, Aqueous Vets was selected over existing industry incumbents to supply the Granular Activated Carbon Systems (GACS) for a Southern California Water Treatment Plant.
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![GettyImages-1298781737 aseptic filling]( "Vaccine Fill Line Operations")
Vaccine Fill Line OperationsLearn how adopting a harmonized, risk-based validation strategy across global sites can reduce operational readiness timelines and drive improvements in equipment effectiveness and regulatory compliance
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![mountaire-farms]( "Enhancing Water Quality For Mountaire Farms")
Enhancing Water Quality For Mountaire FarmsMountaire Farms resolved their wastewater facility issues by replacing mechanical surface aerators with SDOX technology, saving $38 million and improving treatment.
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![Magnifying Glass]( "Flatiron Prospective Evidence Generation")
Flatiron Prospective Evidence GenerationExplore prospective evidence generation and pragmatic approaches that can help you address staffing challenges and the issue of complexity that is driving up the failure rate of clinical studies.
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![GettyImages-1159306148 aeration biosolids]( "Cutting Costs, Not Corners: How PRI-TECH® Transformed Biosolids Odor Control At Bergen Point WWTP")
Cutting Costs, Not Corners: How PRI-TECH® Transformed Biosolids Odor Control At Bergen Point WWTPThe Suffolk County Department of Public Works tested the effectiveness and cost-efficiency of PRI-TECH® in controlling odors at a wastewater treatment plant. The technology successfully treated odors and reduced operating costs.
NEWS
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ZEISS Introduces The New Smartzoom 100: The Future Of Digital Microscopy For Efficient Optical Inspections5/6/2025
ZEISS presents the new ZEISS Smartzoom 100, an innovative digital microscope for fast and efficient quality assurance.
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Masdar And Iberdrola Announce €5.2B UK Offshore Wind Deal And Full Energization Of 476MW German Offshore Wind Farm7/10/2025
Masdar, a global clean energy leader, and Iberdrola, one of the world’s largest energy companies, have reached two major milestones with a €5.2B co-investment in the UK’s East Anglia THREE offshore wind farm – the largest offshore wind transaction of the decade – and the full energization of their 476MW Baltic Eagle project in Germany.
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Brown Astronomers Create New Technique To Eliminate Signals Disrupting Sensitive Radio Telescopes2/12/2025
Astronomers sifting through data from the Murchison Widefield Array, a radio telescope in Western Australia, found themselves confronting an unexpected mystery.
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University Of St. Thomas Offers No-Cost Machining And CNC Optimization Training7/18/2025
The University of St. Thomas is launching a new, no-cost training program to help manufacturing professionals, engineers, and students upskill and gain valuable insights into using computer simulations to optimize CNC machining.
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AEON Biopharma Appoints Industry Veteran Rob Bancroft As Chief Executive Officer4/21/2025
AEON Biopharma, Inc. (“AEON” or the “Company”) (NYSE: AEON), a clinical-stage biopharmaceutical company focused on developing a botulinum toxin complex for the treatment of multiple therapeutic indications, announced today the appointment of Rob Bancroft as President and Chief Executive Officer, effective April 29, 2025. Mr. Bancroft will also join AEON’s Board of Directors.
ABOUT
Harvest and Collection
Harvest and collection is the process used to retrieve biological agents and vaccines present in cell cultures or to harvest and collect stem cells from blood or bone marrow. Many bioresearch companies have sophisticated systems for harvesting and collecting cells. These systems make counting cells easier and they also protect against contamination.
Cells are harvested once the cells reach a density level in the cell culture medium that precludes further growth. The best time to harvest cells is when they are in a confluent state (at least 50% of the culture dish is covered and before 100% of the dish is covered).
Cells can be harvested using on of three methods: Mechanical, using Proteolytic enzymes, or using EDTA. Mechanical harvesting uses a rubber spatula to remove the cells from the growth surface or culture. This method is quick but can cause many cells to die because it is highly disruptive. This method is favored when harvesting lots of different samples of cells to prepare extracts.
In this case, viability of the cells doesn’t matter. Three enzymes; Trypsin, Collagenase, and Pronase can be used in combination with EDTA. The combination of these enzymes with the EDTA makes cells detach from the growth medium.
This method is easy but also has a downside. It can damage the cell surface by eating up exposed cell surface proteins. EDTA can be used alone to detach cells from their medium and it is gentler than using trypsin.
Normally, collected cells are placed in a new suspension, or growth medium to continue growing new cultures. This is referred to as passaging or splitting the cells.