Harvest & Collection
PRODUCTS
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![Getty Images-1087219418-fill-filling]( "Injectable Drug Manufacturing")
From the production floor to the shipping door, your unique clinical or commercial requirements will be fulfilled at each step of the process.
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![PBS Biotech - PBS-1 bioreactor]( "Mini Vertical-Wheel Bioreactor: PBS-0.1")
The PBS-0.1 Mini single use bioreactor is compatible with 60mL-100mL working volumes and is the best starting point for optimizing cell therapies by leveraging the benefits of Vertical-Wheel mixing that can be easily scaled up for larger volumes.
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![GettyImages-1175279159 powder]( "Onsite Preclinical Services To Support Your Product Development: Powder Micromeritics")
Understanding the fine details of powder properties is crucial in the pharmaceutical industry, where the behavior of particulate matter can affect manufacturability and the efficacy of the final product.
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![Med Device Assembly]( "Manufacturing And Device Assembly")
Polyzen is capable of producing virtually a variety of polymer-based component using a wide range of processing equipment. This includes extrusion, molding, forming, and machining equipment.
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![amm-9862psm]( "4 - 40 GHz Wideband Gain Block: AMM-9862PSM")
The AMM-9862PSM is a compact, wideband gain block amplifier designed for high-performance RF applications.
WHITE PAPERS AND CASE STUDIES
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![gulf-coast-refinery]( "Oxygen On Demand: How A Gulf Coast Refinery Overcame High COD Challenges With A Rapid H2O2 Dosing System")
Oxygen On Demand: How A Gulf Coast Refinery Overcame High COD Challenges With A Rapid H2O2 Dosing SystemThe Gulf Coast Refinery approached USP Technologies (USP) to engineer a bulk H2O2 chemical dosing system sized to meet the plant’s D.O. demand
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![twence]( "How ABB Is Helping Optimize Combustion At Twence's Waste-To-Energy Plant")
How ABB Is Helping Optimize Combustion At Twence's Waste-To-Energy PlantMaintaining the right level of oxygen is crucial for combustion optimization. Too much excess oxygen equals decreased efficiency. Read more about how ABB is helping Twence optimize combustion in their waste-to-energy plant in the Netherlands.
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![pinnacle 1]( "Why Sherbrooke, Quebec Chose Pinnacle Zenith Ozone Generators To Boost Water Treatment Efficiency")
Why Sherbrooke, Quebec Chose Pinnacle Zenith Ozone Generators To Boost Water Treatment EfficiencySherbrooke, Quebec upgraded its water treatment plant with Pinnacle’s Zenith ozone system, improving disinfection, reliability, energy efficiency, and operational savings while ensuring future scalability.
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![GettyImages-1499706090 unlock]( "How To Unlock The Secret To Repeatable, Scalable Low Turnover")
How To Unlock The Secret To Repeatable, Scalable Low TurnoverHere, we explore the evolution of a 10-year partnership and extrapolate the principles that create cohesive teams and minimize turnover.
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![GettyImages-1401269015 data computer]( "Biostatistics And Programming — More Than Just Clinical Trials")
Biostatistics And Programming — More Than Just Clinical TrialsSee how our biostatisticians and programmers successfully ingested, cleaned, and analyzed the data, ultimately providing a small biotech company with several interesting and actionable measures.
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![iStock-1206219776-agreement-signature-legal-paperwork]( "End-To-End Clinical, Biometrics, And Regulatory Support In Neurology")
End-To-End Clinical, Biometrics, And Regulatory Support In NeurologyDiscover how an integrated NDA strategy aligned data, vendors, and regulatory execution to achieve an on-time submission and approval without major FDA queries.
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![digital transformation-Digitization of Analog Information-GettyImages-867312356]( "Digitalizing Batch Records In Pharmaceutical Production")
Digitalizing Batch Records In Pharmaceutical ProductionPharma manufacturing embraces cutting-edge automation, yet outdated paper-based documentation hinders efficiency and delays batch releases. See how digital solutions can transform compliance.
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![GettyImages-597972428-adenovirus]( "Development Strategies For Adenovirus-Based Gene Therapies")
Development Strategies For Adenovirus-Based Gene TherapiesScaling up viral vector production can be challenging, and ensuring consistent titers and activity requires careful optimization and technical expertise.
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![BSL-3 Mobile Biocontainment Laboratory]( "BSL-3 Mobile Biocontainment Laboratory For Vaccine Development Research")
BSL-3 Mobile Biocontainment Laboratory For Vaccine Development ResearchThe client required a freestanding COVID-19 research facility on an accelerated timeline built for continuous use in the cold climate of the northeast United States without a shell building.
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![microscope-lab-iStock-909176662]( "Case Study: Recruiting Pediatric Ultra-Rare Disease Patients")
Case Study: Recruiting Pediatric Ultra-Rare Disease PatientsExplore how Rezolute was able to overcome challenges while recruiting pediatric patients for a Congenital Hyperinsulinism (HI) clinical trial using a streamlined, single-source tool.
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![GettyImages-2230840465 pfas chain]( "PFAS Removal System Proven Effective In Removing Both Long And Short Chain PFAS")
PFAS Removal System Proven Effective In Removing Both Long And Short Chain PFASA new system removed all nine PFAS compounds from a municipality's water to non-detect levels in a single pass. Unlike traditional methods, it addresses both long- and short-chain PFAS while generating minimal waste.
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![getty-155067590]( "How GIS Improved Workflows For The Largest Municipal Utility In The U.S.")
How GIS Improved Workflows For The Largest Municipal Utility In The U.S.Read how LADWP updated its workflows and enriched its management of data by implementing a new enterprise-wide GIS platform, based on Esri’s ArcGIS Enterprise, as well as several apps.
NEWS
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FF-10832 Granted FDA Orphan Drug Designation For The Treatment Of Biliary Tract Cancer7/7/2025
FUJIFILM Pharmaceuticals U.S.A., Inc., drug development center and a leading provider of Contract Development and Manufacturing Organization (CDMO) services for drug delivery system (DDS) technologies, today announced that the U.S.
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A Supersolid Made Using Photons3/10/2025
Manuele Landini from the University of Innsbruck was part of an international team led by researchers at CNR Nanotec in Lecce, Italy, that has demonstrated the emergence of a supersolid phase of matter in a photonic crystal polariton condensate.
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NEOVAC Presents Innovative Vacuum Coating Technology For High-Strength Steels With No Thermal Stress8/27/2025
NEOVAC, a joint venture between SMS group GmbH and SITIZN Group Holding AG, based in Karlstein, Germany, is proud to present a brand new technology for coating steel strip, which was specially developed for high-strength and ultra-high-strength steels.
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Rivers Choose Their Path Based On Erosion — A Discovery That Could Transform Flood Planning And Restoration7/10/2025
Rivers are Earth’s arteries. Water, sediment and nutrients self-organize into diverse, dynamic channels as they journey from the mountains to the sea.
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Researchers Uncover Role Of A-Site Cation Ordering In Perovskite Anodes For High-Temperature Oxygen Evolution7/28/2025
Solid oxide electrolysis cells (SOECs) are a leading technology for carbon dioxide reduction and energy conversion, offering high current densities, excellent Faradaic efficiency, and low overpotentials. Perovskite oxides are commonly used as SOEC anodes, yet the impact of A-site cation ordering on their oxygen evolution reaction (OER) kinetics remains unexplored.
ABOUT
Harvest and Collection
Harvest and collection is the process used to retrieve biological agents and vaccines present in cell cultures or to harvest and collect stem cells from blood or bone marrow. Many bioresearch companies have sophisticated systems for harvesting and collecting cells. These systems make counting cells easier and they also protect against contamination.
Cells are harvested once the cells reach a density level in the cell culture medium that precludes further growth. The best time to harvest cells is when they are in a confluent state (at least 50% of the culture dish is covered and before 100% of the dish is covered).
Cells can be harvested using on of three methods: Mechanical, using Proteolytic enzymes, or using EDTA. Mechanical harvesting uses a rubber spatula to remove the cells from the growth surface or culture. This method is quick but can cause many cells to die because it is highly disruptive. This method is favored when harvesting lots of different samples of cells to prepare extracts.
In this case, viability of the cells doesn’t matter. Three enzymes; Trypsin, Collagenase, and Pronase can be used in combination with EDTA. The combination of these enzymes with the EDTA makes cells detach from the growth medium.
This method is easy but also has a downside. It can damage the cell surface by eating up exposed cell surface proteins. EDTA can be used alone to detach cells from their medium and it is gentler than using trypsin.
Normally, collected cells are placed in a new suspension, or growth medium to continue growing new cultures. This is referred to as passaging or splitting the cells.