BioProcess With The Bozenhardts

EPISODES

Bioprocess With The Bozenhardts: Bioprocessing Facilities Of The Future

Thursday, July 15, 2021

How will the bioprocessing facility of the future adapt to meet the therapeutic needs of the day, and well into the future? What evolutionary steps should you be taking today to meet those needs? On this episode of Bioprocess With The Bozenhardts, Herman and Erich Bozenhardt, P.E. are queried by host Louise Hall, PMP as they enter their time machine and hit fast-forward to envision the facilities you'll need to accommodate the future of...  Continue Reading..

• Bioprocess With The Bozenhardts: Evolution Of Biopharma Plant Engineering

  Join Herman & Erich Bozenhardt, PE as they revisit the evolution of biopharma plant engineering in a deep discussion with host Louise Hall, PMP. The Bozenhardts and Hall reflect on how far we've come, and why the lessons we've learned along the journey are so important to charting the course ahead. From aseptic processing to HVAC considerations, the trio leaves no stone unturned in this lively retrospective.

• Bioprocess With The Bozenhardts: Dealing With The Nasties: BL-3, Potent Compounds, Solvents, & Peroxides

  Herman & Erich Bozenhardt, PE are back, joining Louise Hall, PMP for a discussion on equipping your bioprocessing facilities to safely and efficiently handle the potent compounds, solvents, and peroxides used in the production of biologics. The trio discuss the adaptation of technologies and procedures to mitigate risk in the process of manufacturing exosomes, antibody drug conjugates, viral vectors, and more. 

• Bioprocess With The Bozenhardts: Auditing Biotech Facilities

  Are you in the process of planning a new biotech facility? Acquiring an existing facility? Transferring technology to an outsourced partner? Don't miss out on the collective wisdom shared by Louise Hall, PMP, Erich Bozenhardt, PE, and longtime bioprocessing facilities consultant Herman Bozenhardt on this episode of Bioprocess With The Bozenhardts. The trio discusses how to ensure a successful business outcome and check all of your regulatory boxes.

• Bioprocess With The Bozenhardts: Human Tissues: Therapies Derived From Fluids And Cells

  How close are we to taking a tablet and growing a new kidney? Bonus points if you caught the Star Trek reference. On this episode of Bioprocess With The Bozenhardts, Louise Hall, PMP discusses advances in human tissue-based therapies with Erich Bozenhardt, PE and Herman Bozenhardt. Join the conversation for an update on advances to the systems and processes biopharmaceutical companies are using to restore and regenerate disease-affected human tissues.

• Bioprocess With The Bozenhardts: Liposomes In The Era Of COVID-19

  Join Louise Hall, PMP as she queries Herman and Erich Bozenhardt, PE on the resurgence of liposomes in the wake of their role in COVID-19 vaccine and therapeutic development. The trio discuss how the technology has evolved, what we've learned, and what the future holds for the role of liposomes in biotherapeutic development moving forward.

• Bioprocess With The Bozenhardts: Outsourcing Decisions

  Join biopharma facilities and tech transfer expert Louise Hall, PMP for a discussion with Herman and Erich Bozenhardt, PE. on the key considerations biopharma companies should ponder before outsourcing the manufacture of biopharmaceuticals. Beyond cultural match, the Bozenhardts dig into how you should analyze GMP compliance, history with regulatory agencies, and much more. 

• Bioprocess With The Bozenhardts: Cell & Gene Therapy Site Selection

  On this episode of Bioprocess With The Bozenhardts, Erich and Herman share insight into the shortage of manufacturing space for up-and-coming cell & gene therapies, and the factors you'll need to consider—from location to physical infrastructure to utilities—as you plan your biomanufacturing facilities build-out.

• Bioprocess With The Bozenhardts: Filling System Selection

  Bioprocess With The Bozenhardts is back, with a fresh episode packed with advice from Herman and Erich on the selection of filling systems for biopharmas. Listen in as the Bozenhardts give us an update on the process, logistics, and administration trends that are informing filling system decisions today, and offer direction on making choices that will prepare you for the fast-advancing therapies of tomorrow.

• Bioprocess With The Bozenhardts: Biopharma 4.0

  Listen to Herman and Erich define Biopharma 4.0 and discuss how machine learning and artificial intelligence are shaping drug discovery, development, processing, and manufacturing. On this episode of Bioprocess With The Bozenhardts, you'll learn how new technologies will impact your next facility and what elements of Biopharma 4.0 you can put to work for you today.

• Bioprocess With The Bozenhardts: Return Of The Liposome

  Liposomes have benefits, but their production complexity, “shell” deterioration, and particle size variability and distribution make them a production nightmare that is often more of an art than a science. On this episode, Herman and Erich uncover the resurrection of the liposome and offer guidance on its use. 

• Bioprocess With The Bozenhardts: Patient Centricity

  On our first three episodes, Herman and Erich covered the central tenets of bioprocessing facilities design and equipment trends. On this episode, we shift gears a bit and dig into patient centricity, the personal medicine cliff, and how those trends will affect the bioprocessing facilities of the future.

• Bioprocess With The Bozenhardts: Isolators And RABs

  On this episode of Bioprocess With The Bozenhardts, Herman and Erich dig deep into some specific facilities equipment—namely isolators and restricted access barrier systems—with insight and advice on how they fit into your biopharma production processes and the importance of putting the right people behind their controls.

• Bioprocess With The Bozenhardts: Space & Construction Considerations

  Bioprocessing capacity is feeling the strain. Is it time to build? Is it time to buy? Is it time to overhaul, or is it time to outsource? On this episode, Herman and Erich dig into the considerations—some obvious and some not so—that are key to space and biomanufacturing construction decisions.

• Bioprocess With The Bozenhardts: Facilities Design Trends

  On this episode, we kick off the season with a discussion on what's driving the move toward smaller, more agile production facilities, the role these trends play in your business strategy, the physical space, capital, HR, and utilities impacts you'll need to consider to stay ahead of the curve, and whole lot more.

• An Intro To BioProcess With The Bozenhardts: Episode 1

  Herman and Erich Bozenhardt have a collective 55 years of bioprocess facilities design and equipment experience, and they're here to share it all in our fresh Bioprocess with the Bozehardts podcast series. Here's a quick preview of the biweekly deep-dive conversations we'll have with two of the foremost minds in bioprocess facilities engineering.