Upstream Harvest

1. Advantages of Vertical-Wheel Bioreactors For High-Yield PSC Expansion 7/1/2025

   Unlock high yields in pluripotent stem cell expansion. Discover how vertical-wheel bioreactors offer advantages over stir tank systems, with expert guidance on passaging, feeding, and harvesting.

2. Single-Use Centrifuge Cinematic 10/24/2022

   With the DynaSpin Single-Use Centrifuge, minimalism is about intentionality. We designed our automated process with a simplified tubing setup and a substantial reduction in filter usage.

3. Pore Morphology And Pre-Filters 8/2/2024

   Find out how to select a prefilter for sterile filtration applications and recognize the advantages between various membrane morphologies with Chris Rios, Entegris Senior Field Applications Engineer.

4. The Importance Of Upstream–Downstream Coordination 3/9/2026

   In this segment from the Bioprocess Online Live event “Optimizing Process Development Through Upstream And Downstream Integration,” our panelists discuss the challenges development teams face when upstream and downstream teams operate concurrently in a vacuum.

5. CTS DynaCellect Magnetic Separation System Cell Isolation 5/22/2025

   Ready to achieve high-purity results in your cell therapy manufacturing? This step-by-step guide demonstrates the complete setup and installation for your automated magnetic cell isolation system and kit.

6. A Closed And Automated Solution For Cell Therapy Manufacturing 3/1/2024

   Streamline your cell therapy manufacturing process and workflow by automating and closing your cell isolation, cell harvest, and formulation with a system designed to offer you versatility.

7. Where Does Upstream End And Downstream Begin? 3/9/2026

   In this opening segment from the Bioprocess Online Live event, “Optimizing Process Development Through Upstream And Downstream Integration,” our panel of process development experts weighs in on where exactly to draw the line between upstream and downstream development.

8. The Importance Of Process Locks To Align Upstream And Downstream 3/9/2026

   In this closing segment from the Bioprocess Online Live event “Optimizing Process Development Through Upstream And Downstream Integration,” the panelists emphasize the importance of periodic process locks to ensure alignment between upstream and downstream development teams. These locks are critical, says Eric Doerr, a manufacturing lead at Sanofi, because they allow both upstream and downstream to have a better understanding of the process and keep them on the same page.

9. High-Viability Cell Processing, Simplified 10/31/2024

   This scalable, automated system ensures high cell viability and recovery, efficient concentration and washing, and fast processing. Experience the power of tubular bowl technology for optimal cell separation.

10. New Demands On Biopharma Harvest And Clarification 12/16/2021

    New industry trends in upstream processes are introducing higher demands on the harvest and clarification process. Overcome limited design challenges by building on newer technologies capable of simplifying upstream processing.