Product Showcase

  1. Ion Exchangers For Efficient Protein Purification: Praesto SP And Praesto Q

    Praesto SP and Praesto Q are agarose-based ion exchange chromatography media designed for lab- to process-scale purification of recombinant proteins and other biomolecules. Praesto SP and Praesto Q are available in 90 μm, 65 μm and 45 μm particle sizes, covering the use of ion exchange in high-productivity capture steps as well as high-resolution polishing applications.

  2. Late-Phase Protein-A Resin: Praesto AP

    Praesto AP is a Protein-A resin designed on a novel, high-flow agarose backbone, which addresses today s late stage clinical manufacturing challenges for high productivity, together with cost effective MAb capture. It is purpose-designed and evaluated for the production of late-phase clinical trial material, PIII and commercial manufacture, where typically hundreds of reuse cycles are performed.

  3. Early-Phase Protein-A Resin: Praesto APc

    Praesto APc is a Protein A resin designed on a novel high flow agarose backbone which addresses today s early-phase clinical trial challenges for high productivity together with cost effective MAb capture. It is purpose-designed and evaluated for phase I and II clinical trials, where typically less than 20 reuse cycles are performed. Alternatively Praesto APc can be implemented across all phases due to long life time. Before PIII, for innovator therapies, Purolite Life Sciences recommends you then switch from Praesto APc to Praesto AP since they both utilize the same Protein A ligand species.

  4. Early-Phase Protein-A Resin: Praesto AC

    Praesto AC is a Protein A resin designed to address today's clinical manufacturing challenges for high productivity, cost-effective MAb capture. Praesto AC combines good capacity, excellent pressure/flow performance and NaOH CIP stability for up to 20 cycles, meeting the common requirements for production of materials for PI and PII clinical trials. Praesto AC can also be used in small scale MAb purification, purification of MAbs for diagnostics, in process development and in pre-clinical processes

  5. Immobilized Metal Affinity Chromatography Resin

    Metal affinity chromatography was developed for the purification of native proteins with an intrinsic affinity to metal ions. Immobilized metal affinity chromatography (IMAC) has a broad range of applications, although its primary application is for the purification of histidine-tagged recombinant proteins that can bind nickel, cobalt, and copper ions. IMAC is also used for isolating phosphorylated proteins and zinc finger or copper-binding proteins.

  6. Pharmaceutical Flexible Containment Equipment

    DoverPac® Containment Systems, an ILC Dover brand, is the global pioneer of disposable process and powder containment systems.

  7. Continuous Liner Containment For Pharmaceutical And Biopharma Powders

    The DoverPac® Continuous Liner is used for offloading powders from vessels to drums and provides the advantage of replacing follow-on packs without breaking powder containment for continuous production.

  8. Flexible Enclosures For Pharmaceutical And Biopharma Manufacturing

    ILC has adapted the DoverPac® Flexible Containment Technologies to include enclosures for almost any process. Use of the ArmorFlex® film and integral gloves and sleeves will support operations from filter dryer discharge and heel removal to tray dryer loading and unloading. The benefits of this technology are:

  9. Ventilated Enclosure System With Flexible Containment Technologies

    The Ventilated Enclosure System combines the benefits of Flexible Containment with a unique, light weight ventilation unit. This system provides all the advantages of a negative or positive pressure isolator providing reduced costs for cleaning and validation with the disposable enclosure that is utilized.

  10. Single-Use Mixer For Difficult-To-Mix Biopharm Ingredients

    MilliporeSigma’s Mobius® Power MIX 2000 single-use mixing system is engineered with advanced technology to effectively handle difficult-to-mix buffers, culture media powders and other pharmaceutical ingredients. The Mobius® Power MIX achieves a strong vortex using an impeller design and motor based on magnetically-coupled NovAseptic® technology, a proven mixing technology in stainless steel tanks. The Power MIX 2000 provides accessible, sterile zero deadleg sampling directly from the mixing container. A Probe Port allows for insertion of either a reusable probe for non-aseptic processes or a pre-sterilized, single-use sensor for in-process pH measurement of aseptic processes. Other design features make the mixing system easy to use, enabling loading of bags by one person and offering an optional integrated hoist for powder delivery.