Featured Articles
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The Power Couple: CRISPR And Oligonucleotides
1/27/2026
Oligonucleotides are reshaping genetic medicine, with CRISPR accelerating demand for complex gRNA sequences. Learn about the manufacturing challenges that define the next phase of oligo development.
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Purification And QC Of An RNA 21‑Mer Oligonucleotide Via LC‑MS
1/27/2026
Learn how buffer choice, gradient strategy, and pretreatment steps influence recovery, purity, and resolution when purifying a native RNA oligo, with analytical confirmation and practical guidance.
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Scalable, Sustainable Support For Next‑Gen Primer Systems
1/27/2026
Explore how an optimized solid‑support design enables higher synthesis scales, steadier pressures, and lower solvent use while preserving yield and purity across diverse oligonucleotide lengths.
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Lipid Nanoparticles Boost CRISPR HDR Gene Insertion in Human T Cells
12/12/2025
Lipid nanoparticles enable precise, non-viral gene editing in T cells to achieve high HDR efficiency and viability in scalable workflows. Explore how this approach overcomes viral vector limitations.
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Understanding Adeno-Associated Virus Vector Impurities
11/13/2025
AAV vectors hold promise for gene therapy, but removing product-related impurities remains a challenge. Learn how cell line development and process optimization are advancing rAAV production.
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Cell Culture Media Demystified For Performance, Quality, And Innovation
11/13/2025
Cell culture media isn’t one-size-fits-all. Learn how media composition, customization, and analytics can dramatically improve cell growth, productivity, and product quality for complex processes.
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Scale-Up Of A Transient rAAV Production Process
11/3/2025
Scalable rAAV production is achievable with a transient cell line and optimized bioreactor setup, delivering high titers and reduced impurities, now validated at 200 L scale for commercial readiness.
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Scale-Up Of An Adherent rAAV Production Process
11/3/2025
Fixed-bed bioreactors simplify the scale-up of viral vector production. Discover a system that bridges development and manufacturing with data confirming consistent performance across scales.
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A Simple Method For Cell Growth Media Preparation
11/3/2025
Explore how powder media and sterile fluid handling can reduce contamination risk and improve efficiency in viral vector production, especially for HEK293-based AAV workflows.
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Exosome Production From hMSC Using A Fixed-Bed Bioreactor
11/3/2025
Explore a high-yield, scalable process for hMSC-derived exosome production using fixed-bed bioreactors, with strong performance in purity, recovery, and biological activity.