908 Devices Application Notes
-
Are You Getting The Cell Culture Media You Expected?
1/21/2022
Consistency between cell culture media vendors should not be assumed. In some cases, certain media components can be as high as 2.5x the expected values.
-
Identify Variations In Chemically-Defined CHO Media Dry And Liquid Formulations
1/20/2022
Running a quick media assay prior to a run ensures consistency of the media components during the transition between liquid-to-dry media blends.
-
Assessing The Differences In Fresh Commercially Available Hybridoma Media
1/20/2022
The concentrations of media components are essential to consider when doing media optimization studies. Quick analysis is key to optimize the process.
-
Analyze Media Without Removing Your mAb
1/18/2022
Cell media analysis becomes challenging when faced with high concentrations of a protein. New mass spec-based analyzers offer a faster and simpler alternative.
-
Select The Best Chemically Defined CHO Media From The Start
1/18/2022
A key aspect of process development is optimizing cell culture media. Whether media is sourced in-house or externally, it is vital to ensure consistency.
-
Monitor Nutrients And Metabolites In Cell Culture Media To Improve Yield
1/11/2022
Spent media analysis should no longer be a lengthy process. See how an at-line analyzer removes process bottlenecks and speeds up process development.
-
Analysis Of Biologics For Similarity Assessment Using CZE-MS Quick Assessment
10/13/2021
A quick study of a mAb for fast assessment can help save time and reduce bottlenecks with mass spectrometer usage for busy analytical laboratories.
-
Quantification Of Metabolites In Chemically Defined Media
10/8/2021
When measuring analytes in complex cell culture media media method accuracy and reproducibility are critical. The right analyzer provides rapid, reliable, quantitative media analysis.
-
How To Maintain Your Bioreactor's Health And Drive Production Of Drug Product
10/8/2021
This demonstration for biotherapeutic proteins manufacturers, shows how combining CZE separations with MS detection can eliminate the derivatization step, and simplify sample preparation.
-
High-Throughput Intact Mass Analysis Of mAb-Based Therapeutics
10/8/2021
Review a method for high throughput analysis of monoclonal antibodies using a simple approach that can facilitate rapid MS characterization of biotherapeutic proteins.