908 Devices Application Notes

1. Comparison To And Advantages Over Traditional Chemometrics Models 4/5/2024

   As Raman spectroscopy, with partial least squares (PLS) models, becomes more popular in bioprocesses applications it's important to recognize the challenges this approach presents.

2. On-line Measurement Of Glucose & Lactate With Automated Feedback Control 10/3/2023

   Achieve continuous, on-line monitoring with measurements as often as every two minutes, with no loss of bioreactor volume and no risk of contamination.

3. Enabling Real-Time Process Control 10/3/2023

   Defined control strategies enable more intensified and stable cell culture processes such as perfusion which may see dramatically improved productivity.

4. Glucose And Lactate Raman-Based Monitoring System 9/27/2023

   Evaluate the consistency, linearity, and specificity of a plug-and-play, in-line, Raman-based PAT solution that typically provides measurements with a precision of <0.1 g/L for both glucose and lactate.

5. Investigating The Similarities Between Different Vendors’ 2X YT Liquid Media 2/2/2022

   Identifying variations in the expected nutrient profile before its use may prevent undesirable culture outcomes like poor growth and low productivity.

6. Probing Formulation Differences In Super Optimal Broth 2/2/2022

   Uniformity among SOC media vendors should not be assumed. Testing media before the start of culture ensures that nutrients in a media are at a desirable level.

7. Investigating The High Nutrient Variations In Super Optimal Broth 2/1/2022

   The extremely high variability in the individual media components’ concentrations suggests little similarity across different commercial sources of SOB media.

8. High Variations Of Analyte Levels Are Detected In Terrific Broth (TB) Media 2/1/2022

   Exact concentrations of media components may differ due to raw material inputs. These differences may affect the culture’s growth or productivity.

9. How Comparable Are Different Vendors’ LB Media? 2/1/2022

   Using an at-line analyzer to quickly screen different vendor’s LB media may support reproducible cultures and media preparations for bacterial cultures.

10. Don’t Let FBS Disrupt Your Cell Culture Media Nutrient Analysis 1/31/2022

    Support reproducible culture processes and media preparations for a variety of cell lines by routinely monitoring slight changes in media components as the serum is added to the basal media formulations.