
REPLIGEN – PAT
Repligen is a bioprocessing-focused life sciences company bringing over 40 years of expertise and innovation to our customers. We are inspiring advances in bioprocessing through the development and commercialization of high-value products and flexible solutions that address critical steps in the production of biologic drugs, principally monoclonal antibodies.
Repligen headquarters is in Waltham, Massachusetts and our manufacturing facilities are located around the world. We market our products globally through a direct commercial organization in the U.S., Europe and Asia, as well as through strategic partners in select markets.
VIDEOS
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Discover a device that measures and controls critical bioprocess parameters in cell culture that uses an intuitive interface and Raman-based PAT solution for real-time monitoring and remote access.
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Discover a device that precisely controls glucose and lactate in cell culture and fermentation to reduce manual labor, contamination risks, and cell stress while offering remote data viewing and automated control.
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Unlock real-time insights into your processes with PAT solutions to enhance your understanding, productivity, and quality while reducing manual sampling and contamination risks through fast, frequent analytics.
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Get faster process insights and dynamic control of substrate feeding without the loss of bioreactor or fermenter volume.
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There’s no need to deal with complex empirical calibration models, reagents, or unreliable auto-sampling systems to implement in-line bioreactor monitoring.
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Powered by Raman spectroscopy and a purpose-built de novo model, this platform performs simultaneous real-time measurements of multiple key process parameters in mammalian cell cultures.
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You need rapid and reliable nutrient profiles to make informed decisions, and waiting on that data has detrimental effects on your process. See how REBEL fills the gap.
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The REBEL is a an automated benchtop analyzer for targeted cell media analysis called. The data provided by the system may accelerate process development analytics by days to weeks over traditional core lab or 3rd-party test practices.
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In two minutes, watch how to load a sample and run this powerful analyzer that can provide results on 30+ cell media analytes. Waiting for a report on the core lab can be a thing of the past if you can simply analyze a sample right from your lab bench.
WEBINARS
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Linking mAb Product Quality Profile Changes To Your BioProcess: A Case Study
Optimize your bioprocess and product quality with high-frequency data. Discover how to streamline mAb characterization and link process changes to product attributes.
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Keeping Up With New Emerging Analytical Technology
Explore advancements in emerging analytical technologies like Process Analytical Technology (PAT) and mass spectrometry, improving drug development through enhanced bioprocess monitoring and control.
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Instant Implementation Of Raman-Based Monitoring
This platform, based on Raman technology with a de novo approach, operates as effortlessly as a pH-meter, providing real-time measurements of key process parameters such as glucose, lactate, and biomass.
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Now Starts Now: The Future of Glucose And Lactate Measurement
Explore a platform that addresses the challenges of on-line nutrient and metabolite monitoring and control.
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In-line Monitoring Of Bioprocess Parameters For The 21st Century
Review the current state of several optical technology approaches and their associated strengths and limitations along with new and transformative means to instantly implement in-line monitoring.
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Addressing Upstream Cell Culture Challenges As A Community
John Hopkins University's Michael J. Betenbaugh speaks to the Advanced Mammalian Biomanufacturing Innovation Center's work with new data sources to improve process modeling.
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Mass Spectrometry For Biopharmaceutical Process Development
Learn how at-line analytics are valuable for process modeling and biosimulation through topics such as digital design and modeling cell culture processes.
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Controlling Essential Amino Acid Levels In CHO Cell Cultures
Listen to a dynamic discussion on the highlights of a new peer-reviewed article exploring model-based approaches to cell culture optimization.
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The Criticality Of Cell Culture Media Analysis For Cell & Gene Therapies
This short webinar explores what is already known about cell culture media analysis, reviews at-line methods for cell culture media analysis, and shares recent data from two case studies.
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Process Intensification: Do You Have All the Data You Need When You Need It?
This webinar reviews how at-line mass spec-based technologies provide key cellular metabolic and protein quality data in real time to support process intensification and modelling.
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The Importance Of Cell Media Analysis In Upstream Bioprocess Development
Experts from industry and academia to explore current trends in upstream bioprocessing and the impact of real-time cell media analysis on process improvements and process analytical technologies.
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Rapid Cell Culture Media Analysis For C> Process Development
Experts discuss how to accelerate process analytics with fast nutrient screening at critical time points and the benefits of rapid media analysis in cell therapy development and viral vector production.
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Drive Productivity By Tracking Key Nutrients In Your Bioreactor
Watch this on-demand webinar to learn about technological breakthroughs that now allow for rapid at-line analysis of cell media. You’ll learn the fundamentals about this new technology, how and why to track key nutrients in your bioreactor, how to adjust your feed strategy based on rapid insights, and how to monitor consumption trends to drive high productivity.
CONTACT INFORMATION
Repligen – PAT
41 Seyon Street, Building 1, Suite 100
Waltham, MA 02453
UNITED STATES
Phone: 781-250-0111
HOT PRODUCTS
BROCHURES
FEATURED ARTICLES
APPLICATION NOTES
- A Dilute-And-Shoot Method For Monitoring mAb PQAs From Spent Media
- Sensitive Screening Of Biosimilar Candidate mAbs From Clonal Cell Lines
- Assessing mAb Quality Through Direct Spent Media Analysis
- Data-Driven CHO Bioprocess Optimization And Scale-Up
- Amino Acid Analysis Indicates Metabolic Differences In MCB CAR T-Cells
- Instant PAT Implementation Across Cell Lines, Media, And Scales
- Real-Time Monitoring Of Key Bioprocess Parameters
- Continuous Monitoring And Control Of Glucose And Lactate
- Analyzing Critical Quality Attributes Of Monoclonal Antibodies
- In-line, Raman-Based PAT Solution For Monitoring And Control