ABOUT CULTURE BIOSCIENCES
At Culture Biosciences, we partner with Biopharma/Biotech clients who develop gene and protein therapies accelerating cell culture process development (PD). Culture utilizes innovative cloud-connected bioreactors and data science capabilities driving the digital transformation of biomanufacturing. Culture’s real-time data analysis and data-driven modeling capabilities enable clients to accelerate their biomanufacturing screening and optimization work. Culture has worked with over 70 clients collaborating with PD labs on design of experiments (DoE), debottlenecking PD and de-risking outcomes.
FEATURED ARTICLES
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![Culture Bio Process Dev.]( "InSiliCHO: Modeling Cell Line Dynamics For Process Development")
Modeling and simulation can be a powerful tool for bioprocess design. Find out how you can utilize an open source implementation for in silico simulation of CHO.
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![Culture Scientists]( "Best Practices In Fermentation Bioprocess Development")
Stefan De Kok, Director of Fermentation at Zymergen, shared his work in biomanufacturing R&D, as well as the DARPA project he worked on and the importance of fermentation expertise in biomanufacturing.
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![Laboratory bioprocess iStock-1144377258]( "The Biggest Challenges Of Bioprocessing And How to Overcome Them")
Dr. Kris Tyner, a subject matter expert in bioprocessing, shares his experience and thoughts on simplifying bioprocessing, gathering answers faster, and de-risking while scaling up.
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![GettyImages-1399936043 cloud data]( "Technical Transfers: Ensuring Successful Scaling Of Client Processes")
Optimize your technical transfer process using built-for-purpose, cloud-connected systems and obtain results that translate effectively to other facilities.
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![450x300_Laptop]( "Generate High Quality Data And Execute Full Factorial Design Of Experiments")
Learn how a bioprocessing company supplemented their in-house bioreactor capacity and performed large-scale DOE studies using a cloud bioreactor facility.
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![image_bior_lab]( "Supplemental Bioreactor Capacity Accelerates Bioprocess Development")
Explore a successful collaboration where a fermentation process was transferred, downscaled, modified, and improved via a DOE, then verified and transferred back in just a few experiments.
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![Cell and Gene genetic lab Getty Images-1209892070]( "Running Statistically Powered Clone Screening Experiments")
Discover how conducting a power analysis can determine the correct sample size for a statistically powered clone screening experiment.
CONTACT INFORMATION
Culture Biosciences
269 E Grand Ave.
South San Francisco, CA 94080
UNITED STATES
Contact: Contact@culturebiosciences.com
APPLICATION NOTES
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![GettyImages-1297393276 Scientist using computer in lab]( "Bakuchiol Synthesis Optimization In S. Cerevisiae During Scale Up")
Explore the significance of cost-effectiveness in synthetic biology and the successful scaling up of a process involving S. cerevisiae for the production of bakuchiol.
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![Cloud]( "Scaling Up mAb Process Development To A 5L Bioreactor")
This technology transfer study, conducted with cloud-connected bioreactors designed to accommodate CHO cells, compares results obtained from various shake flask cultures.
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![GettyImages-1499121682 data]( "Ensure Data Quality Through Mass Balance Calculations")
Improve your cell line performance and process optimization using a cloud bioreactor that enable accurate, real-time monitoring of the whole cell culture fluid mass.
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![Adeno-Associated Virus (AAV) iStock-1086530854]( "Using 250mL Bioreactors For AAV Production")
This demonstration examines an AAV upstream process in proprietary bioreactors, including an example of using process optimization to increase the fraction of full AAV capsids.
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![Scientists In Lab Working Together On Digital Tablet GettyImages-893884830]( "Precision Volume Accounting In Fed-Batch Cultures")
Are you searching for a better way to calculate growth rate? Explore a new approach that performs the rate calculations using a simple method to correct for volume changes.
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![Scientist laboratory ipad GettyImages-500323894]( "Robust Off-Gas Analyzers For High-Throughput Bioreactor Facilities")
Learn about an off-gas analysis system for bioreactors that can provide slightly faster response times than commercially available analyzers.
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![450x300_5L]( "Modeling And Online Estimation Of kLa And P/V")
Explore continuous models of kLa and P/V in 250mL and 5L bioreactors in order to scale-up and compare bioreactor performance metrics.
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![450x300_Microbial]( "Highly-Reproducible Results With A High-Throughput Bioreactor System")
Are you looking for ways to reduce bioprocess development time and scale-up? Learn the details behind a high-throughput bioreactor system with the ability to generate high quality, reproducible data.
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![CHOcc]( "Reproducible And Scalable System For CHO Cell Culture")
Explore a demonstration of a 250mL bioreactor system designed to run off site in the cloud, as well as the results of it's use in both cell culture and fermentation applications.
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![450x300_Cloud]( "Accurate Cell Culture Characterization")
Achieve fast, accurate knowledge extraction from cell culture experiments, while also calculating growth rates, consumption rates and comparing variability in cell lines using a cloud native platform.
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![image_mammalian]( "Mammalian Bioreactors: A Characterization Data Report")
Review experiments that characterize the basic operating conditions of mammalian cultures in single-use bioreactors and parameters to be used when transferring cultures to/from other bioreactor systems.
