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For high concentration monoclonal antibody formulations, aggregation is a known issue. Read how we optimized tangential flow filtration (TFF) formulation in combination with single-pass TFF (SPTFF) to reach 200 g/L of a monoclonal antibody using Delta 30 kDa TFF membranes.
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Read how Fujifilm selected an effective filter for their process after evaluating Supor™ Prime filter and two others. They used challenging simulant solutions that were both viscous and liable to filter fouling.
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Want to learn how Supor™ Prime filters compare to other sterilizing filters on the market? This comparison study compares the throughput performance of three different filters in a range of moderate to high concentrations of mAbs and IgG.
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Watch our on-demand webinar to learn the challenges and gain practical solutions for high concentration drug manufacturing.
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A general introduction to the principles and applications of tangential flow filtration using systems and filters from Cytiva. Detailed instructions for preparing, using, cleaning and storing particular filters are provided with each filter.
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