Win The Race Against Time When Developing Biosimilars Of Tocilizumab

A growing demand for biosimilars has only added to the fierce competition of drug development. On such a front, time is of the essence and there is an urgent need for robust analytical tools for various stages of biosimilar development. This application note discusses the use of a bi-functional analytical tool, Maurice, in the stability study of Actemra® (Tocilizumab). As a popular monoclonal antibody used for treating rheumatoid arthritis, and more recently, in the treatment of COVID-191, Tocilizumab has several biosimilars in the pipeline of various biopharmaceutical companies. In this study, we demonstrate how Maurice accurately detects and quantitates changes in Tocilizumab under various stress conditions, thus making it a valuable and easy-to-use tool for comparability assessments in biosimilar development.