What To Know About CRISPR Screens And Bulk Spheroid Production

Promising new technologies are enabling the use cancer spheroids, an up-and-coming group of models, to make break throughs in cancer research. The combination of bulk spheroid production and CRISPR screening, is an area of particular interest. Both spheroid and organoid 3D culture models allow researchers to study cancer and other diseases in a more physiologically relevant setting while lessening the reliance on model animals.

Could your research team benefit from bulk spheroid production for screens? And how are genome-wide CRISPR screens used to explore cancer biology?