What Is Mixed-Mode Chromatography?

There are a variety of advantages of mixed-mode interactions have been observed beyond simply finer discrimination between product and impurities. Learn more in this discussion of Mixed-Mode Chromatography and how these tools provide greater resolution compared to unimodal interaction, improved yield and activity via advantageous use of charge-charge repulsion between ligand and protein, larger design space for protein binding, minimal feed manipulation prior to binding, and mild operating conditions preserve activity.