5 Ways To Keep Your CHO Cells Happy In A Bioreactor

By Tony Allman

CHO (Chinese Hamster Ovary) cells are the most commonly used resource for complex recombinant proteins for therapeutic use and are growing in importance for bioprocessing. Even a baseline bioreactor, which is simply run-in batch mode, can produce results as good or better than shake flasks with larger volumes and will ensure an increased level of process control. To advance CHO cell lines in mainstream bioprocessing, researchers should know what is required of a cell culture bioreactor. Explore the key features for successful CHO cell culture in the bioreactor, including slow and gentle mixing, a high-end gassing system, foam prevention, accurate feeding, and sterile sampling.