VirusExpress® 293 AAV Production Platform Data Sheet
Source: MilliporeSigma
The VirusExpress® Platform offers a transfection-based solution to Adeno-Associated Viral (AAV) production challenges, featuring a suspension adapted cell line, chemically defined medium, and a clinically relevant process dramatically reducing time to commercial production. VirusExpress® offers the flexibility to use either our contract manufacturing capabilities or your own facilities to speed your therapy to patients.
Our VirusExpress® Platform offers:
- A transfection-based solution to adeno-associated viral (AAV) upstream production challenges
- A suspension adapted cell line of 293 AAV Production Cells optimized for production of AAV vectors for gene therapy applications
- Chemically defined medium to alleviate animal origin and supply chain concerns
- Proven process performance at 3 L scale with genome titer exceeding 8 x 109 gc/mL
- Comprehensive user protocols to guide from seed train through at-scale transfection and virus production, allowing for seamless scale-up
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