Utilization Of Titration Curve Modeling In Bioassay Potency Method Development

Contract laboratories are time constrained which affects provider and client. This is especially notable for Cell Based Testing Teams, where the assays vary due to growth condition variability and the plotting of titration curves to accurately measure any effect on the targeted mechanism of action. To overcome this, the Cell Based Assay Team at KBI uses a modeling tool to predict the cellular response to an agonist or antagonist.