04.11.25 -- Using Digital Shadows To Reinforce Downstream Modeling

Cell and gene therapies require adaptive and advanced assays for characterization and safety assessments, and assays historically used for biologics must diversify to accommodate them.

A DIY quantum scanning microscope is a viable option for users who prefer to modify the experiment setup or cannot reserve adequate time on a shared instrument.

Discover how this solid-state HDX-MS is being used to revolutionize the prediction of stability for IgG-based Antibody Drug Conjugates and enhance ADC development processes.

Learn how to optimize AAV manufacturing with a transfection reagent and enhancer platform that boosts titers and percent full capsids by 2- to 10-fold, featuring insights from real-world case studies.

As the landscape of CAR T-cell therapies evolves, these treatments are becoming more precise in targeting cancer cells and overcoming production challenges, and are poised to revolutionize oncology.

Understanding the Fc region of your antibody is crucial for assessing the impact on immunology, safety, and efficacy. Explore how to determine the most efficient way to test functionality.

Discover how decades of research have propelled mRNA technology to the forefront of therapeutic development and learn how our expertise is advancing mRNA drug development.

For tablet manufacturers, tablet weight uniformity plays an essential role in ensuring pharmaceutical products deliver accurate amounts of key ingredients in a formulation.

Learn why a strong commitment to operator training is essential to prevent production issues, ensure product quality, and safeguard patient safety.

Review a modeling approach employing artificial neural networks using experimental factors combined with simulation-derived parameters plus viscosity data from 27 highly concentrated mAbs.

Discover how implementing a strategic approach to optimize the platform can establish a solid foundation for the efficient, reliable, and successful manufacturing of biopharmaceutical products.

Review the elements of a complex process, prone to misconceptions and pitfalls, to find the “right human tissue” that will yield the desired cell quality and quantity and pass BLA approval.

Explore the vital role of drug formulation in transforming biologics into patient-friendly therapies, and uncover key insights into this critical process from lab to clinical trials.

Strategically optimize your upstream and downstream processes and decrease the timeline from optimization to commercial manufacturing.

To prepare for an FBS shortage, secure reliable suppliers, validate backups, stock reserves, and consider alternative sourcing. Corning offers high-quality FBS and expert supply planning support.

Discover how a vendor-independent partner assists global life science companies and CDMOs with innovative single-use technologies to mitigate risks and ensure uninterrupted manufacturing.

An alternative to traditional polyethylene bags is offering cell and gene therapy manufacturers a solution to contamination concerns regarding DNA or RNA fragments.

Learn more about a flexible freeze container that maintains package integrity after freezing at -86 °C. 
(-123 °F) through its durable design, minimizing product loss due to package failure.