Application Note

Use Of Sodium Hydroxide For Cleaning And Sanitization Of Chromatography Resins And Systems

Source: Cytiva

Sodium hydroxide is widely accepted for cleaning and sanitization of chromatography resins and systems. The benefits of its use include efficacy, low cost, and ease of detection, removal, and disposal. As with any sanitizing agents, certain precautions should be taken and compatibility with both chromatography resins and systems determined.

This application note examines these aspects of using sodium hydroxide as a cleaning and sanitizing agent. Many examples of particular interest to producers of recombinant proteins, monoclonal antibodies, and oligonucleotides are included, as designing and scaling up validatable cleaning processes are critical issues in the commercial manufacture of these products.

VIEW THE APPLICATION NOTE!
Signing up provides unlimited access to:
Signing up provides unlimited access to:
  • Trend and Leadership Articles
  • Case Studies
  • Extensive Product Database
  • Premium Content
HELLO. PLEASE LOG IN. X

Not yet a member of BioProcess Online? Register today.

ACCOUNT SIGN UP X
Please fill in your account details
Login Information
I'm interested in newsletter subscriptions.
ACCOUNT SIGN UP

Subscriptions

Sign up for the newsletter that brings you the industry's latest news, technologies, trends and products.

You might also want to: