Case Study

Use Of High Cell Density Cryopreservation For Seed Train Intensification


During the upstream workflow, a seed train scales a small volume of cell culture to a larger volume to first inoculate intermediate bioreactors, and then the production bioreactor. This step can be time consuming using the traditional expansion process. In contrast, seed train intensification techniques such as high cell density cryopreservation (HCDC) can accelerate and streamline the process.

Learn about seed train expansion using HCDC, the benefits of this technique, and more.

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