Upstate Introduces Pathway Profiler™ Service; Offers Faster, More Complete View Of Cellular Response

Upstate Group, Inc., a Serologicals (NASDAQ: SERO) company announced today the introduction of PathwayProfiler™, a new service that measures cell-based signaling cascades (cell communication pathways) and provides drug development companies with a unique insight into their therapy and its efficacy in the cell. PathwayProfiler™ is the only service of its kind currently available.

PathwayProfiler™ assesses drug effectiveness at various concentrations, simultaneously on multiple targets in a single sample and on multiple cell types or cells derived from various disease states. It offers greater ease and convenience for quantitative investigation of cell signaling in a native cellular environment for customer specified analytes. This analysis aids the researcher to develop a more complete understanding of in vivo compound efficacy in a wide variety of cellular environments. In addition to CytokineProfiler™, used for measuring cytokines, Upstate offers the most comprehensive quantitation of signal transduction molecules available.

"PathwayProfiler™ is an excellent follow-up to the KinaseProfiler™," said Ian Ratcliffe, President of Upstate. "It will dramatically accelerate the speed at which we are able to provide results to customers and, consequently, compress the time traditionally spent for the drug screening procedure. In addition to this new service, our plan is to aggressively add even more new content and capability to "PathwayProfiler™ in the future."

Used primarily by pharmaceutical firms engaged in cancer research, the Pathway Profiler™ service is also appropriate for diabetes, inflammation, angiogenesis and other researchers. PathwayProfiler™ is based on unique technology developed by Upstate over the last decade.

Upstate is a leading research discovery provider of the highest quality cell signaling products and services to the life science market. Its customers are biomedical researchers at drug discovery companies and academic institutions in the key disciplines of oncology, immunology, proteomics, cardiology and neurology. Known for its enabling, innovative solutions to help understand the biology of kinases, chromatin, g-proteins and cytokines, Upstate's advanced cell biology tools - drug screening services, enzymes, state specific antibodies, siRNA kits, multiplex assays are used by thousands of customers worldwide, every day to accelerate improving human health. Upstate, a Serologicals company, is located in Lake Placid, NY, Dundee, Scotland and Charlottesville, VA.