Unlocking The Future: Exploring Cutting-Edge Cell And Gene Therapies

By Robert Ossig, Process & Manufacturing Technology

Explore the transformative potential of cutting-edge cell and gene therapies, focusing on CAR-T cell therapy, CRISPR-Cas9 gene editing, and other advanced approaches. CAR-T therapy involves engineering patient T cells to target and destroy cancer cells, exemplified by Kymriah for leukemia and lymphoma. CRISPR-Cas9 enables precise DNA modification to correct genetic disorders, with CTX001 targeting sickle cell disease and beta-thalassemia. Additionally, stem cell therapies, oncolytic viruses, mRNA-based treatments, and AAV-mediated gene therapies offer new solutions for a range of conditions, from cancer to genetic disorders. These advancements represent a significant leap in medicine, aiming to provide long-term, effective treatments by addressing diseases at their root causes.