Understanding EndoCleave's Role In Viral Vector Manufacturing

The production of safe and effective viral vectors is paramount in gene therapy and vaccine development. A critical challenge in achieving the required purity lies in the efficient removal of contaminating host cell DNA and residual plasmid DNA, which can impact product safety, immunogenicity, and overall efficacy. EndoCleave, a high-performance endonuclease, addresses this challenge head-on by selectively degrading all forms of DNA and RNA while preserving the integrity of vital protein components, including viral capsids. Its GMP Grade quality and antibiotics-free production ensure it meets the stringent demands of biopharmaceutical manufacturing.

Understanding how to leverage EndoCleave effectively can significantly enhance the purity and safety profile of your viral vector products. Dive deeper into this application note to learn more.