Newsletter | June 17, 2026

06.17.26 -- Tools And Technologies Enabling Next-Generation Cell Therapies

Activation Methods For Yielding Expansion Of Gamma Delta T Cells

Gamma delta T cells are emerging as a promising platform for cancer immunotherapy. In this webinar, we compare two clinical-scale expansion strategies that generate billions of highly functional gamma delta T cells, highlighting their potential for clinical-grade adoptive cell therapies.

 

A Chemically Defined Medium Supports Cross-Platform T-Cell Expansion

Human serum has long been a critical component of CAR-T cell manufacturing, but its cost, variability, contamination risks, and limited supply present significant challenges for large-scale production. This poster introduces a chemically defined, serum-free medium that supports superior T-cell expansion and optimized culture practices.

 

Cytokines For Ex Vivo Cell Culture

Optimizing cytokine selection is essential for producing high-quality CAR-T cell therapies, and this study evaluates the performance of TheraPEAK AmpliCell Cytokines (IL-2, IL-7, and IL-15) against a leading competitor. The results in this application note demonstrate comparable cell expansion, viability, and CAR-T functionality.

 

Enhancing CRISPR Knock-In And Knock-Out

Efficient and scalable delivery of CRISPR/Cas9 components is critical for advancing gene and cell therapies, and electroporation has emerged as the leading non-viral approach for clinical applications. Here, we demonstrate how the 4D-Nucleofector LV Unit PRO enables robust, scalable T-cell gene editing workflows.

 

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