Product/Service

The World's First Imaging Microhub Mica

Leica Mica

This changes everything.

More than a highly automated microscope, Mica unites widefield and confocal imaging in a sample protecting, incubating environment. With the simple push of a button, you have everything you need - all in one place - to supercharge fluorescence imaging workflows and get meaningful scientific results faster.

Now you can focus on your science, not figuring out your microscope.

  • Access for all

  • No constraints

  • Radically simplified workflows

Access for all

Everyone can now leverage microscopy to make more discoveries.

Mica provides a clear sample overview and allows to easily change observation conditions with just a few clicks.

  • 85% fewer steps to the first image

  • 33% less time to the first image

  • 50% of the training time

No constraints - 4x more data with 100% correlation

The Microhub enables you to simultaneously capture all 4 labels of different structures in a single acquisition for widefield or confocal, without ever moving your sample. This overcomes the spatiotemporal mismatch between labels of moving objects during sequential acquisition. All powered by our patented FluoSync technology, a fast and gentle method for multicolor fluorescence imaging.

No constraints - Select the right modality in real time

Mica unifies transmitted and fluorescence light imaging modalities. You can select from multiple imaging modalities all within one Microhub, including widefield, confocal, THUNDER imaging, LIGHTNING, Z-stacks, time-lapse and more.

This enables you to

  • generate fast overviews with widefield at low magnification

  • gradually zoom in on the regions of interest

  • switch to confocal when and where needed without ever moving the sample to a different system

No constraints - Achieve physiological-like conditions throughout your experiments

Live cell experiments require the cells to be in optimal shape. Typically, 2D and 3D cells in media require the temperature and the pH (via CO2) in the environment to be controlled. Stable nutrition and ion concentrations require the evaporation to be minimal. Some experiments even demand the O2 to be mimicked closer to physiological levels. Mica can provide the right conditions in the live cell configuration.

  • Mica is an incubator: the entire encapsulated inner sample space can be climate controlled (temperature, CO2 and humidity regulation) and offers ideal conditions for short and long-term live cell observation.

  • From dark to light: Mica also enables you to enjoy a brightly lit lab—freeing you from the constraints of sitting in a dark room for hours monitoring your experiment.

Radically simplified workflows

Intelligent automation and AI-supported analysis enables greater efficiency and a faster track to publication.

  • Reduce over 60% of process steps through system intelligence

  • Reduce time and effort from sample to insight by simplifying your entire workflow

  • Enable 100% reproducibility and repeatability throughout your experiment

Key applications

  • Fluosync

  • Image Acquisition

  • Microhub imaging

  • Multiplexing

  • Spatial Biology

  • Widefield Microscopy

  • Fluorescence

  • Live Cell Imaging

  • Confocal Microscopy

  • Image Analysis

  • DAPI

  • Cell Biology

  • Cancer Research

  • Organoids and 3D Cell Culture

  • Model Organisms in Research

  • Neuroscience

The Microhub era is now!

Experience the future.