The Role of Droplet Digital™ PCR In Developing Safe And Effective AAV-Based Gene Therapies

By Mark White, Bio-Rad Laboratories, Inc.

Droplet Digital PCR (ddPCR™) technology is becoming an appealing alternative to quantitative PCR (qPCR) for many gene therapy applications involving gauging AAV viral titers. Accurately measuring viral titer is a key metric throughout gene therapy development, whether you are in the early stage, scaling production, or running assays for quality control release. As gene therapies become more common, the need to quantify viral particles and contaminants with new, efficient tools will only increase. Learn how Droplet Digital PCR (ddPCR) technology offers the accuracy to quantify AAV viral titers to support many aspects of AAV-based gene therapy development.