Newsletter | June 23, 2025

06.23.25 -- The Promise And Challenges Of Cell-Free Protein Systems

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Explore the latest biotech equipment and solutions — all online, wherever you are.

Don't miss the next Bio-Expo Live! This interactive, multi-day event is organized by stages of drug development and production, making it easy to find sessions tailored to your company's needs. Browse the full agenda and register for free to join the conversations most relevant to your work.

FOCUS ON UPSTREAM MANUFACTURING

The Promise And Challenges Of Cell-Free Protein Systems

CFPS use cell lysates or purified enzymes to synthesize proteins. They have emerged as a promising alternative to production with living cells.

Exploring Perfusion Technology For Manufacturing Process Intensification

Perfusion cell culture technology supports high cell densities and product yields for viral vaccine manufacturing, offering a reliable way to produce high-quality cells at a commercial scale.

A Fed-Batch hMSC-EV Bioprocess Medium Enabling 2-4x EV Yield Improvements In Bioreactor Culture

A new chemically defined fed-batch bioprocess medium simplifies hMSC-EV production, increasing yields by 2-4x while maintaining EV quality across donors and tissue types in scalable environments.

Challenges And Solutions For Viral Product Development, Manufacturing

To execute complex viral product manufacturing, a service provider needs expertise in adherent cell culture capabilities, cell line productivity, and the intricacies associated with these products.

Epitope Base Editing CD45 Enables Universal Blood Cancer Immune Therapy

Researchers developed base-edited CAR T cells and CD45-edited stem cells to create universal blood cancer immunotherapy, showcasing efficacy while minimizing toxicity using electroporation technology.

Driving Efficiencies: The Power Of Platform Processes And Digital Access

Unlocking the potential of next-generation therapeutics requires extending the boundaries of both expression system technology and process development and manufacturing.

Why Cell Washing Is The Hidden Bottleneck In Gene-Edited Cell Therapy

Scaling up life-saving gene-edited cell therapies means tackling production inefficiencies. Overcoming the time-consuming and risky cell washing step is crucial for clinical and commercial success.

Make Media And Buffers Your Competitive Advantage

Find out how you can simplify the process of media design and customization, reduce cost, and facilitate sustainable science with high quality GMP products.

Sustainable Manufacturing Through Efficient BioProduction Unit Operations

Explore critical environmental and economic aspects of bioprocessing, like the urgent need to manage the industry’s growing plastic waste issue and a three-pronged approach to address this challenge.

PSC Perfusion Guidance Using Vertical-Wheel Bioreactors

Unlock the potential of perfusion for pluripotent stem cell cultures. Explore key insights into achieving improved consistency and quality in your medium exchange protocols, leading to better outcomes.

UPSTREAM MANUFACTURING SOLUTIONS

High Quality Water: Cell Culture, Molecular Biology, Reagent Grade - Corning Life Sciences

An Incubation Shaker For Uninterrupted 24/7 Operation - INFORS HT

Plant 5 — Dream Plant: Within Your Reach. Built For Your Success. - Samsung Biologics

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