Application Note

The Latest Generation Protein A Resin - DurA Cycle A50

Chromatography GettyImages-1392302602

Designed for the purification of a wide range of mAbs and constructs, the DurA Cycle A50 is the latest generation protein A resin. Using Jetting technology these resins are manufactured to produce higher yields with less waste. The new DurA Cycle A50 ligand engineering enables milder pH elution for non VH3 containing molecules when compared to commercially available agarose protein A competitors.

Other Key Benefits Include:

  • High dynamic binding capacity allowing for increased processing per gram mAb per cycle
  • Good pressure flow properties for scalability
  • Maintains capacity under varying cleaning strategies
  • Improved protease stability for more challenging harvests resulting in low protein A leakage
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