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| Webinar: Defined Media, Defined Results: Scaling E. coli from Bench to Fermenter | Microbial systems power plasmid DNA and recombinant protein production, but scaling introduces variability. This webinar explores how chemically defined media can improve performance, reproducibility, and animal-origin-free workflows. Experts share beta-test results from E. coli cultures using defined formulations, plus practical insights on integrating them into workflows and scaling from experiments to fermenter production for reliable manufacturing outcomes. Click here to learn more. |
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FOCUS ON UPSTREAM MANUFACTURING |
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By Better Biopharma | In this closing segment from the Bioprocess Online Live event, the panelists emphasize the importance of periodic process locks to ensure alignment between upstream and downstream development teams. These locks are critical, says Eric Doerr, a manufacturing lead at Sanofi, because they allow both upstream and downstream to have a better understanding of the process and keep them on the same page. | |
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| Confidently Scaling-Up Microbial Fermentation | Article | INFORS HT | Successful microbial scale-up hinges on ensuring process consistency, optimizing yield, and simplifying compliance. Learn strategies to overcome key challenges in bacterial, fungal, or yeast fermentation. |
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| Redefining T Cell Culture Media | Article | By Asma Ayari, Ph.D., Nucleus Biologics | Media selection is key to CAR-T cell success. Examine how a serum-free, xeno-free medium boosts transduction efficiency, maintains quality, and streamlines the path to clinical scale-up. |
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| A Beginner's Guide To Mesenchymal Stem Cell Culture | Application Note | By Min Tang-Schomer and Ma Sha, Eppendorf SE | Get a foundational understanding of the process for culturing mesenchymal stem cells in stirred-tank bioreactors and learn about the key parameters for successful scale-up. |
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| Webinar: Turbocharge CAR-T Manufacturing: Industrializing Cell Therapy with Perfusion | As allogeneic CAR-T therapies scale, manufacturing intensification becomes essential for speed and cost efficiency. This Repligen webinar explores how XCell? ATF perfusion technology enables rapid, high-density CAR-T expansion in stirred-tank bioreactors while maintaining critical quality attributes. Learn how optimized perfusion, predictive scale-down modeling, and automated harvest integration support consistent production, improved yields, and scalable, economically viable CAR-T manufacturing. Click here to learn more. |
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UPSTREAM MANUFACTURING SOLUTIONS |
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