10.12.26 -- The Hidden Downstream Risks Of Upstream Process Decisions

See how CRISPR-generated FKRP knockout muscle cells and a high-throughput On-Cell Western method can quantify α-dystroglycan glycosylation restoration and support rAAV-FKRP potency testing.

Multiplex engineering of T cells for solid tumors requires precise delivery. Emerging LNP approaches enable co-delivery of RNA and DNA, offering a safer, more scalable path beyond viral vectors.

Potency assays for ATMPs demand precision. Learn how a matrix approach, regulatory alignment, and advanced technologies can overcome variability and ensure safety throughout the product lifecycle.

Drive successful MSC therapy development by optimizing isolation methods, surface chemistry, and closed-system expansion technologies to ensure cellular stability and commercial scalability.

Legacy methods often mask critical impurities. Discover why traditional blotting may be jeopardizing your regulatory data and how to implement more sensitive, objective alternatives.

Animal models are giving way to iPSC-based systems that better reflect human biology, offering researchers a more accurate and ethical path to drug discovery.

Examine an automated strategy for enriching CD34+ cells, combining streamlined processing, strong purity and viability metrics, and reduced hands-on effort to support stem cell engineering.

Discover how precise downstream glycan engineering addresses biopharma pain points, extending therapeutic half-life and ensuring absolute analytical similarity for biosimilars.

Choosing licensed vs. unlicensed cell lines impacts development speed, cost, flexibility, and long‑term control, making early strategic evaluation key to efficient biologics development.

Achieve greater sequence diversity in antibody discovery. Learn about an approach that enables reproducible and scalable transfections, leading to the identification of better candidates.

Choosing the right transfection reagent can be confusing. This guide explores product names, their applications, and the importance of testing beyond labeled uses.