The Cell Proliferation Guide

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The cell proliferation guide offers insights into the necessary tools and techniques for staining and scoring cell proliferation, a process vital for evaluating cell health, gauging reactions to toxic insults, and diagnosing cancers. The guide emphasizes prevalent methods for marking and scoring cell proliferation, such as examining DNA levels or synthesis, cellular metabolism, and specific proteins associated with proliferation. Among the most effective techniques for studying cell proliferation are the use of Ki67 for fixed samples and EdU for live cells. The guide also notes the potential of MCM-2 as a prognostic marker in specific cancers.
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