Successful Scale-Up Of An Upstream Viral Vector Process Using An Adherent Platform

Cell and gene therapies hold promise for treating diseases that were once considered incurable, with viral vectors being the most commonly used method for gene delivery. To fulfill patient demands, it is essential to establish dependable and cost-efficient manufacturing methods. However, scaling up viral vector production for commercial use is complex, and the lack of standardized procedures presents significant obstacles that can delay therapy development and affect productivity. Selecting the right production system is crucial to meeting commercial timelines while controlling manufacturing expenses.

This webinar provides a comprehensive case study of a helper-dependent adenovirus (HDAd) process, covering everything from bench-scale optimization to successful scale-up and tech transfer using adherent culture. Watch and learn how to transform small-scale expression systems into a scalable, efficient process.