Streamlining Antibody Capture With Multi-Column Chromatography

The biopharmaceutical industry is continually exploring innovative approaches to enhance the efficiency and cost-effectiveness of manufacturing processes, particularly for complex biologics such as monoclonal antibodies (mAbs). While traditional batch chromatography remains a cornerstone of biomanufacturing, it presents several challenges that can hinder both productivity and profitability. High resin costs, coupled with underutilization of resin capacity, often lead to increased operational expenses. Additionally, the physical footprint required for batch chromatography systems can be less than ideal, demanding significant space and resources. These limitations become especially impactful for small to medium-sized biotech companies, who may face tight budgets and space constraints.

As these companies strive to develop and scale new therapies, overcoming these challenges is crucial to improving both the efficiency and affordability of biopharmaceutical production, ultimately driving the availability of life-saving treatments to patients more quickly and at a lower cost.