Webinar | February 11, 2021

Scale-Up Of An Antibody Production Workflow From Bench To Pilot/Production

During cell culture scale-up, a process optimized at small scale needs to be reproduced at larger scales, ideally without much need for process optimization at large working volumes. This requires reproducing the quality of the seed culture and the cells’ growth environment across all scales. Here, we detail the techniques needed for the scale-up of an antibody production workflow using CHO cells from bench to pilot/production scale and illustration how the novel scale-up assist software featured in the BioFlo 720 bioprocess control station can support scale-up strategy design.

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