Scalable Manufacturing Of Human Mesenchymal Stem/Stromal Cells And Induced Pluripotent Stem Cells

Stem cell therapies hold immense promise for regenerative medicine and tissue engineering. However, the scalable manufacturing of stem cells remains a significant challenge. Traditional methods, such as static culture flasks, are limited in their scalability and often result in inconsistent cell quality. Vertical-wheel bioreactors (VWBRs) have emerged as a promising alternative, offering several advantages for stem cell expansion, including improved mass transfer, controlled shear stress, and scalability.

This poster presents the scalable manufacturing of human mesenchymal stem/stromal cells (hMSCs) and induced pluripotent stem cells (hiPSCs) in VWBRs. The results demonstrate the potential of VWBRs for the efficient and scalable production of high-quality stem cells for therapeutic applications.

Topics covered in this poster:

• Human Mesenchymal Stem/Stromal Cells (hMSCs) Grown on The Surface Of Microcarriers In Vertical-Wheel Bioreactors
• Human Induced Pluripotent Stems (hiPSCs) Grown as Cell Aggregates In Vertical-Wheel Bioreactors

Download the poster to learn more about the advantages of VWBRs for stem cell manufacturing.