Role Of Interconnectivity In Enabling Improved Bioprocess Quality

By Christiane Schlottbom, Claudia M. Huether, Dr. Karl Rix, Melissa M. St. Amand, and Babatunde A. Ogunnaike

Information technology helps to integrate Quality by Design (QbD) and Process Analytical Technology (PAT) into standard laboratory procedures and increase efficiency in process and product development. The presented case study demonstrates how novel information technologies of an advanced Eppendorf DASGIP® Parallel Bioreactor System improved process development. Seamless integration of analytical data allowed for implementation of a predictive model control and comprehensive process automation.