Robust, Scalable Manufacturing: N-Linked Glycan Analysis For Complex Glycoproteins

The client had an established cell line and a bench-scale manufacturing process for a complex glycoprotein that produced high quality material but had a low yield and was not scalable. With plans to move into clinical development, the challenge for AGC Biologics was to develop a robust, scalable manufacturing process for this molecule, including defining the glycosylation parameters, implementing AGC Biologics’ glycan assay, and meeting the client’s production level requirements.

Learn how the client achieved a robust process for producing high-quality material at scale.