Residual iPSC And Genomic Stability Testing With High Multiplex Digital PCR

Developing safe and reliable iPSC‑derived therapies demands highly sensitive tools that can track residual undifferentiated cells and monitor genomic integrity with confidence. See how advanced digital PCR workflows enable precise quantification of low‑abundance RNA markers and support amplitude-based high multiplex assays capable of analyzing up to 12 targets in a single reaction. By partitioning samples into thousands of nanoliter wells, the approach delivers exceptional accuracy, making it possible to detect rare residual cells at levels as low as 0.001% and to evaluate copy number variation across key genomic regions. The combination of sensitivity, precision, and throughput provides a strong foundation for in‑process monitoring, quality control, and stability assessment across iPSC research and manufacturing.

Access the full poster to see example datasets, assay designs, and multiplexing strategies that can elevate complex cell therapy workflows.