Reproducible And Scalable System For CHO Cell Culture: 250mL Cloud Bioreactor

By Michael McSunas, Alex Krueger, Saede Moseley; Mattie Coacher, Collin Edington, Max Gilbert, Helen Luo, Deborah Pascoe, Fre Tachea, Masaki Yamada

Running benchtop bioreactors, while an economical option, still requires significant resources, infrastructure, staffing, and time. The ongoing industry trend toward miniaturization seeks to address the costs of small scale development and improve operational efficiency. As part of this process, a 250mL bioreactor system that runs off site and in the cloud has been built. This demonstration shows the reproducible outcomes in Culture Biosciences' cloud bioreactors and successful scale-down from a customer’s 1L glass benchtop system.