Rapid High-Resolution Screening Of Plasma B Cells to Identify Antibody Lead Candidates

Bruker Cellular Analysis is highlighting how a Plasma B discovery workflow was used by Abveris, a monoclonal antibody discovery partner, to perform high-throughput, high-resolution screening of plasma B cells to rapidly select antibody lead candidates. Many biopharmaceutical companies are incorporating enhanced methods and technologies to keep up with the demand for new therapeutics and generate antibodies against these difficult targets to accelerate their drug development timeline.

Abveris has successfully developed adherent cell-based assays for the discovery of antibodies against challenging targets that can neither be expressed in soluble form nor in suspension cells. These capabilities all contribute to lower development costs and a faster path for new therapeutics to the clinic.